Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/- |
Location | 2174414..2175047 | Replicon | chromosome |
Accession | NZ_CP015594 | ||
Organism | Acinetobacter sp. NCu2D-2 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A172YQR9 |
Locus tag | A3K93_RS10395 | Protein ID | WP_067731168.1 |
Coordinates | 2174414..2174797 (-) | Length | 128 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | A0A172YR14 |
Locus tag | A3K93_RS10400 | Protein ID | WP_067731169.1 |
Coordinates | 2174790..2175047 (-) | Length | 86 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
A3K93_RS10380 | 2169880..2172066 | - | 2187 | WP_067731165.1 | TRAP transporter large permease subunit | - |
A3K93_RS10385 | 2172224..2172805 | - | 582 | WP_067731166.1 | rhombosortase | - |
A3K93_RS10390 | 2172886..2173917 | - | 1032 | WP_067731167.1 | hypothetical protein | - |
A3K93_RS10395 | 2174414..2174797 | - | 384 | WP_067731168.1 | hypothetical protein | Toxin |
A3K93_RS10400 | 2174790..2175047 | - | 258 | WP_067731169.1 | succinate dehydrogenase assembly factor 2 | Antitoxin |
A3K93_RS10405 | 2175232..2176404 | + | 1173 | WP_067731170.1 | acyl-CoA dehydrogenase family protein | - |
A3K93_RS10410 | 2176462..2177952 | - | 1491 | WP_067731171.1 | NAD(P)/FAD-dependent oxidoreductase | - |
A3K93_RS10415 | 2178159..2178524 | - | 366 | WP_004691290.1 | 50S ribosomal protein L17 | - |
A3K93_RS10420 | 2178543..2179550 | - | 1008 | WP_004869497.1 | DNA-directed RNA polymerase subunit alpha | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 128 a.a. Molecular weight: 15295.30 Da Isoelectric Point: 9.1426
>T63224 WP_067731168.1 NZ_CP015594:c2174797-2174414 [Acinetobacter sp. NCu2D-2]
MDSRCFKLKRSWFALGFQLLIFIILMFVLYQLVPLWLWAMCVIAGLVMYQLFYQKSPKIDQFEYLDGREWSISCQDQVKR
VEISHVIDHQVYIVVYFRHAKARPLLIWCDQLPMQQWKALKAFTQLA
MDSRCFKLKRSWFALGFQLLIFIILMFVLYQLVPLWLWAMCVIAGLVMYQLFYQKSPKIDQFEYLDGREWSISCQDQVKR
VEISHVIDHQVYIVVYFRHAKARPLLIWCDQLPMQQWKALKAFTQLA
Download Length: 384 bp
>T63224 NZ_CP015594:c2174797-2174414 [Acinetobacter sp. NCu2D-2]
ATGGATAGTCGCTGTTTTAAGCTGAAACGCAGTTGGTTTGCGCTTGGGTTTCAGCTTTTGATTTTTATTATATTGATGTT
TGTATTGTACCAGTTGGTGCCACTGTGGTTATGGGCGATGTGTGTGATCGCAGGACTGGTGATGTATCAACTGTTTTATC
AAAAATCACCTAAGATTGATCAGTTTGAATATTTGGATGGACGGGAATGGAGTATTTCTTGTCAAGACCAAGTCAAACGG
GTTGAGATTAGCCATGTGATCGATCATCAAGTGTATATCGTGGTGTATTTTCGTCATGCTAAAGCACGTCCACTCTTGAT
TTGGTGTGATCAATTGCCTATGCAACAATGGAAAGCCTTAAAAGCATTTACCCAGCTTGCTTGA
ATGGATAGTCGCTGTTTTAAGCTGAAACGCAGTTGGTTTGCGCTTGGGTTTCAGCTTTTGATTTTTATTATATTGATGTT
TGTATTGTACCAGTTGGTGCCACTGTGGTTATGGGCGATGTGTGTGATCGCAGGACTGGTGATGTATCAACTGTTTTATC
AAAAATCACCTAAGATTGATCAGTTTGAATATTTGGATGGACGGGAATGGAGTATTTCTTGTCAAGACCAAGTCAAACGG
GTTGAGATTAGCCATGTGATCGATCATCAAGTGTATATCGTGGTGTATTTTCGTCATGCTAAAGCACGTCCACTCTTGAT
TTGGTGTGATCAATTGCCTATGCAACAATGGAAAGCCTTAAAAGCATTTACCCAGCTTGCTTGA
Antitoxin
Download Length: 86 a.a. Molecular weight: 10155.59 Da Isoelectric Point: 4.7132
>AT63224 WP_067731169.1 NZ_CP015594:c2175047-2174790 [Acinetobacter sp. NCu2D-2]
MTDDISLEERKVIYRARRGLKEIDVYFDPYVKNHYLSASAEEKQMFADLVAQEDPDLLDWFMEVSEPPRPELKDFIKKLK
FYVHG
MTDDISLEERKVIYRARRGLKEIDVYFDPYVKNHYLSASAEEKQMFADLVAQEDPDLLDWFMEVSEPPRPELKDFIKKLK
FYVHG
Download Length: 258 bp
>AT63224 NZ_CP015594:c2175047-2174790 [Acinetobacter sp. NCu2D-2]
ATGACTGATGACATCAGCCTAGAAGAACGCAAAGTCATTTACCGCGCACGTCGTGGTTTAAAAGAAATTGATGTATATTT
TGATCCGTATGTGAAAAATCACTATTTGTCGGCATCTGCGGAAGAAAAACAGATGTTTGCAGATTTAGTTGCACAAGAAG
ATCCAGATTTACTCGATTGGTTTATGGAAGTCTCTGAGCCACCACGTCCTGAATTAAAAGATTTTATTAAGAAGTTGAAA
TTTTACGTTCATGGATAG
ATGACTGATGACATCAGCCTAGAAGAACGCAAAGTCATTTACCGCGCACGTCGTGGTTTAAAAGAAATTGATGTATATTT
TGATCCGTATGTGAAAAATCACTATTTGTCGGCATCTGCGGAAGAAAAACAGATGTTTGCAGATTTAGTTGCACAAGAAG
ATCCAGATTTACTCGATTGGTTTATGGAAGTCTCTGAGCCACCACGTCCTGAATTAAAAGATTTTATTAAGAAGTTGAAA
TTTTACGTTCATGGATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A172YQR9 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A172YR14 |