Detailed information of TA system TA063214

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 390090..390994
• Replicon: chromosome
• Accession: NZ_CP015581
• Organism: Tatumella citrea strain ATCC 39140

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: A7K99_RS01985
• Protein ID: WP_087487047.1
• Coordinates: 390536..390994 (+)
• Length: 153 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: A7K99_RS01980
• Protein ID: WP_087487046.1
• Coordinates: 390090..390539 (+)
• Length: 150 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A7K99_RS01960	385707..386789	-	1083	WP_087487042.1	LacI family DNA-binding transcriptional regulator	-
A7K99_RS01965	386908..387882	-	975	WP_087487043.1	hypothetical protein	-
A7K99_RS01970	388055..388603	-	549	WP_087487044.1	hypothetical protein	-
A7K99_RS01975	388930..389898	+	969	WP_087487045.1	helix-turn-helix domain-containing GNAT family N-acetyltransferase	-
A7K99_RS01980	390090..390539	+	450	WP_087487046.1	DUF2384 domain-containing protein	Antitoxin
A7K99_RS01985	390536..390994	+	459	WP_087487047.1	RES family NAD+ phosphorylase	Toxin
A7K99_RS01990	391247..392032	-	786	WP_087487048.1	SDR family oxidoreductase	-
A7K99_RS01995	392084..392983	-	900	WP_087487049.1	GntR family transcriptional regulator	-
A7K99_RS02000	393169..393981	+	813	WP_087487050.1	ABC transporter substrate-binding protein	-
A7K99_RS02005	394009..394734	+	726	WP_087487051.1	amino acid ABC transporter permease	-
A7K99_RS02010	394752..395477	+	726	WP_198361156.1	amino acid ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-146)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (34-91)

Sequences

Toxin

Protein

• Length: 153 a.a.
• Molecular weight: 16621.19 Da
• Isoelectric Point: 4.7483

>T63214 WP_087487047.1 NZ_CP015581:390536-390994 [Tatumella citrea]
MILYRLTKTRYLSSAWSGLGAKQAGGRWNSVGIAMVYLSETASLTMLETLVHLNAPQLLGSFTLLSIEVPENQIMLFDQD
MLPADWAAEDAPAILAQYGDDWAAGAQSVALRIPGALSPVEYNFLFNPLHPAVAGLMYTVRAIPFSFDSRLK

Nucleotide

• Length: 459 bp

>T63214 NZ_CP015581:390536-390994 [Tatumella citrea]
ATGATCCTCTACCGGCTCACCAAAACCCGCTATCTGTCGTCTGCCTGGTCCGGGTTGGGGGCGAAACAAGCCGGTGGCCG
TTGGAACAGTGTCGGCATCGCGATGGTTTATCTGTCGGAGACGGCGTCACTGACTATGCTGGAAACGCTGGTGCATCTGA
ATGCCCCTCAGCTACTCGGGTCCTTTACTCTGCTGAGTATTGAAGTGCCGGAAAATCAGATAATGTTATTTGATCAGGAT
ATGTTACCGGCCGACTGGGCCGCCGAAGATGCCCCGGCCATTCTGGCGCAATACGGCGACGACTGGGCAGCAGGCGCTCA
GTCGGTGGCGCTGCGTATCCCTGGTGCACTCTCGCCGGTAGAATATAACTTTCTGTTCAATCCGCTTCATCCGGCAGTGG
CTGGTCTGATGTACACTGTGCGGGCCATCCCGTTTAGTTTTGATTCACGCCTGAAATAG

Antitoxin

Protein

• Length: 150 a.a.
• Molecular weight: 16717.15 Da
• Isoelectric Point: 8.6356

>AT63214 WP_087487046.1 NZ_CP015581:390090-390539 [Tatumella citrea]
MTMKVFSPSVARVPTADLWSVVGLEVQDGIALMGRISEGLEGDVARRFSDWTNIPASELRKMSGIPNTTFNRSIKARFTA
DQSERIIRVIRVLARAIELFEGDKEAANQWLNEKNRALNWQKPADVLSSETGALEVMRLITRIEHGVYS

Nucleotide

• Length: 450 bp

>AT63214 NZ_CP015581:390090-390539 [Tatumella citrea]
ATGACTATGAAAGTGTTTTCGCCTTCGGTAGCCCGTGTTCCGACTGCTGACCTGTGGAGTGTCGTCGGGCTTGAGGTGCA
GGATGGGATCGCGCTGATGGGCAGAATCAGCGAGGGTCTGGAAGGAGATGTCGCCAGGCGTTTTTCTGACTGGACCAATA
TTCCGGCCAGTGAACTGCGTAAAATGTCGGGTATCCCTAACACCACCTTTAACCGCAGCATTAAGGCCCGGTTTACCGCC
GATCAGAGCGAGCGAATTATTCGGGTGATCCGGGTACTGGCGCGCGCCATTGAACTGTTTGAAGGGGATAAGGAAGCCGC
TAACCAATGGCTGAATGAGAAAAACCGCGCCCTTAACTGGCAAAAGCCTGCGGATGTTCTGTCGTCAGAAACCGGGGCGC
TGGAGGTGATGCGGTTGATTACGCGGATTGAGCACGGCGTTTATTCATGA