Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 3201657..3202168 Replicon chromosome
Accession NZ_CP015515
Organism Rathayibacter tritici strain NCPPB 1953

Toxin (Protein)


Gene name relB Uniprot ID A0A169C758
Locus tag A6122_RS14590 Protein ID WP_068256402.1
Coordinates 3201902..3202168 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A160KVC3
Locus tag A6122_RS14585 Protein ID WP_068256399.1
Coordinates 3201657..3201905 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6122_RS14565 3197109..3197732 + 624 WP_068256389.1 hypothetical protein -
A6122_RS14570 3197844..3198902 + 1059 WP_068256392.1 DUF916 domain-containing protein -
A6122_RS14575 3198978..3200372 + 1395 WP_068256394.1 sugar porter family MFS transporter -
A6122_RS14580 3200476..3201495 - 1020 WP_146076688.1 hypothetical protein -
A6122_RS14585 3201657..3201905 + 249 WP_068256399.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
A6122_RS14590 3201902..3202168 + 267 WP_068256402.1 Txe/YoeB family addiction module toxin Toxin
A6122_RS14595 3202215..3203930 - 1716 WP_068256405.1 hypothetical protein -
A6122_RS14600 3204203..3204844 - 642 WP_068256408.1 NAD(P)-binding domain-containing protein -
A6122_RS14605 3204966..3205949 + 984 WP_068256411.1 acetylxylan esterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-71)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10391.79 Da        Isoelectric Point: 7.2012

>T63153 WP_068256402.1 NZ_CP015515:3201902-3202168 [Rathayibacter tritici]
VTPRTLAWTAEAWEDYLSWQSQDRRTLRRLNLLIADVLRDDPFEGIGKPEPLKHALVGAWSRRIDETNRLIYLADDARIT
ILQARYHY

Download         Length: 267 bp

>T63153 NZ_CP015515:3201902-3202168 [Rathayibacter tritici]
GTGACTCCCCGCACTCTCGCCTGGACGGCCGAGGCCTGGGAGGACTACCTCTCTTGGCAGTCCCAGGACCGGCGGACGCT
CCGTCGGCTGAACCTCCTCATCGCCGATGTGCTCCGAGACGACCCGTTCGAGGGCATTGGCAAACCCGAGCCCCTCAAGC
ATGCATTGGTGGGAGCCTGGTCGCGGCGCATCGATGAGACGAACAGGCTCATATACCTCGCCGACGACGCTCGCATCACA
ATTCTCCAAGCGCGCTATCACTACTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9211.35 Da        Isoelectric Point: 4.6882

>AT63153 WP_068256399.1 NZ_CP015515:3201657-3201905 [Rathayibacter tritici]
MAITTSEARRDLFGLIERVNLDHTEVEITSKRGSAVLMSKDEYDSLVETSHLLRSPENARRLLSALESARSGDVVERELL
EP

Download         Length: 249 bp

>AT63153 NZ_CP015515:3201657-3201905 [Rathayibacter tritici]
ATGGCAATCACCACGAGCGAAGCACGACGAGACCTCTTCGGGTTGATCGAGCGGGTCAACCTCGATCACACGGAGGTGGA
GATCACCTCGAAGCGCGGGTCCGCCGTGCTGATGTCCAAGGACGAGTACGACTCGCTGGTCGAGACCAGCCACCTCCTGC
GCTCCCCGGAGAACGCGCGTCGTCTGCTCTCCGCCCTCGAGAGCGCCCGCAGCGGCGACGTCGTCGAGCGGGAGCTCCTC
GAGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A169C758

Antitoxin

Source ID Structure
AlphaFold DB A0A160KVC3

References