Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1838905..1839050 Replicon chromosome
Accession NZ_CP015500
Organism Klebsiella pneumoniae strain SKGH01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1838941..1839043 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1838905..1839050 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7B01_RS09040 1834035..1836095 + 2061 WP_004151449.1 oligopeptidase B -
A7B01_RS09045 1836099..1836758 - 660 WP_002911407.1 exodeoxyribonuclease X -
A7B01_RS09050 1836837..1837067 - 231 WP_002911406.1 DNA polymerase III subunit theta -
A7B01_RS09055 1837180..1837554 + 375 WP_039819395.1 CopC domain-containing protein YobA -
A7B01_RS09060 1837558..1838427 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
A7B01_RS09065 1838444..1838782 + 339 WP_002911404.1 YebY family protein -
- 1838905..1839050 - 146 - - Antitoxin
- 1838941..1839043 + 103 - - Toxin
A7B01_RS32630 1839419..1839562 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
A7B01_RS09075 1839667..1840635 - 969 WP_014907334.1 VirK/YbjX family protein -
A7B01_RS09080 1840792..1841445 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
A7B01_RS09085 1841442..1841633 - 192 WP_002911395.1 YebW family protein -
A7B01_RS09090 1841731..1841970 - 240 WP_002911393.1 YebV family protein -
A7B01_RS09095 1842086..1843519 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T63119 NZ_CP015500:1838941-1839043 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT63119 NZ_CP015500:c1839050-1838905 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References