Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1770735..1771251 Replicon chromosome
Accession NZ_CP015453
Organism Dietzia psychralcaliphila strain ILA-1

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag A6048_RS08070 Protein ID WP_107747659.1
Coordinates 1770735..1770992 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag A6048_RS08075 Protein ID WP_107747658.1
Coordinates 1770994..1771251 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6048_RS08040 1765778..1766011 + 234 WP_107747665.1 heavy-metal-associated domain-containing protein -
A6048_RS08045 1766104..1768104 + 2001 WP_107747664.1 cadmium-translocating P-type ATPase -
A6048_RS08050 1768234..1768659 + 426 WP_107747663.1 cupin domain-containing protein -
A6048_RS08055 1768769..1769674 + 906 WP_107747662.1 NADP-dependent oxidoreductase -
A6048_RS18485 1769934..1770194 + 261 WP_200837311.1 WhiB family transcriptional regulator -
A6048_RS08065 1770311..1770583 - 273 WP_107747660.1 XRE family transcriptional regulator -
A6048_RS08070 1770735..1770992 - 258 WP_107747659.1 Txe/YoeB family addiction module toxin Toxin
A6048_RS08075 1770994..1771251 - 258 WP_107747658.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
A6048_RS08080 1771927..1773438 - 1512 WP_107747657.1 amidase -
A6048_RS08085 1773505..1774464 + 960 WP_159110211.1 alpha/beta fold hydrolase -
A6048_RS08090 1774585..1774983 - 399 WP_107747720.1 DoxX family membrane protein -
A6048_RS08095 1775125..1775565 + 441 WP_107747719.1 MarR family transcriptional regulator -
A6048_RS08100 1775627..1776064 - 438 WP_107747655.1 PaaI family thioesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1691863..1777629 85766


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10345.74 Da        Isoelectric Point: 8.8042

>T63099 WP_107747659.1 NZ_CP015453:c1770992-1770735 [Dietzia psychralcaliphila]
VLLVWDENAWQGYLWRQQQDRKILKRIYSPLLDITRNGNDGIGKPEPLKYDFAAYWSRRITDEHRLVYKVTETEVRVATC
RYHYE

Download         Length: 258 bp

>T63099 NZ_CP015453:c1770992-1770735 [Dietzia psychralcaliphila]
GTGCTGCTGGTCTGGGACGAGAACGCATGGCAGGGCTACCTCTGGCGGCAACAACAGGACCGAAAGATCCTCAAGAGGAT
CTACAGTCCCCTACTCGACATCACACGCAACGGCAATGACGGTATCGGCAAACCCGAACCCCTCAAGTACGACTTCGCAG
CATACTGGTCCAGGCGAATTACCGATGAACACCGCCTCGTCTACAAAGTCACGGAGACGGAAGTCCGCGTCGCCACTTGC
CGCTACCACTATGAATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9778.92 Da        Isoelectric Point: 4.6899

>AT63099 WP_107747658.1 NZ_CP015453:c1771251-1770994 [Dietzia psychralcaliphila]
MKTMSYTESRARYAEVLDGVTNDREEVVITRAGHEPVVMVSLDDYESLRETAHLMRSPANARRLLDSMERLEDFRGQTRG
FLDAD

Download         Length: 258 bp

>AT63099 NZ_CP015453:c1771251-1770994 [Dietzia psychralcaliphila]
ATGAAGACTATGAGCTACACCGAGTCCCGAGCGCGCTACGCCGAGGTCCTTGACGGGGTCACCAACGACCGCGAAGAGGT
CGTCATCACACGGGCTGGCCACGAGCCGGTGGTCATGGTCTCCCTGGATGACTACGAGTCACTGCGCGAGACAGCTCACC
TGATGCGATCCCCCGCCAACGCCCGTCGACTCTTGGACTCAATGGAACGGCTCGAGGATTTCCGCGGTCAGACCCGCGGC
TTCCTCGACGCCGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References