Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 188679..189153 Replicon chromosome
Accession NZ_CP015449
Organism Dietzia lutea strain YIM 80766

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A6035_RS00805 Protein ID WP_108846222.1
Coordinates 188679..188942 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag A6035_RS00810 Protein ID WP_108848990.1
Coordinates 188926..189153 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6035_RS00790 184704..185735 - 1032 WP_159149555.1 hypothetical protein -
A6035_RS00795 186373..186651 - 279 WP_108846220.1 WhiB family transcriptional regulator -
A6035_RS00800 187237..188391 - 1155 WP_108846221.1 hypothetical protein -
A6035_RS00805 188679..188942 - 264 WP_108846222.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A6035_RS00810 188926..189153 - 228 WP_108848990.1 ribbon-helix-helix protein, CopG family Antitoxin
A6035_RS00815 189326..190306 - 981 WP_108846223.1 cation transporter -
A6035_RS00820 190439..190918 - 480 WP_200836386.1 transporter substrate-binding domain-containing protein -
A6035_RS00825 191113..191531 - 419 Protein_162 ChaB family protein -
A6035_RS00830 191887..192138 - 252 WP_108848992.1 acyl carrier protein -
A6035_RS00835 192450..192803 + 354 WP_108846224.1 hypothetical protein -
A6035_RS00840 192800..193591 + 792 WP_108846225.1 NAD(P)H-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10186.80 Da        Isoelectric Point: 9.5967

>T63097 WP_108846222.1 NZ_CP015449:c188942-188679 [Dietzia lutea]
MTWQIELDDDARKALRKLDKPTAQRIVKKLREVEALADPTDMGKPLTANRAGFWVYRVGDYRLVCDIQFGRLVVLVIEVQ
HRSENYR

Download         Length: 264 bp

>T63097 NZ_CP015449:c188942-188679 [Dietzia lutea]
TTGACCTGGCAGATTGAGCTAGACGATGACGCCCGCAAGGCGTTACGCAAGCTCGACAAACCCACCGCCCAGCGGATCGT
CAAAAAGCTCAGAGAAGTAGAGGCCCTCGCCGACCCGACCGACATGGGCAAGCCGCTGACGGCGAACCGAGCCGGGTTCT
GGGTCTACCGCGTGGGCGACTACCGCCTGGTCTGCGACATTCAGTTCGGCCGACTAGTCGTACTTGTTATCGAGGTCCAA
CATCGCAGCGAAAACTACCGCTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8737.90 Da        Isoelectric Point: 5.2375

>AT63097 WP_108848990.1 NZ_CP015449:c189153-188926 [Dietzia lutea]
MTTTVRLPKDLEERLARVAKGTGRPKSHYLRSLLEENIERLEWEAKLEEKVADIRAGRRRTYSLDEVEAELDLAD

Download         Length: 228 bp

>AT63097 NZ_CP015449:c189153-188926 [Dietzia lutea]
ATGACCACAACAGTTCGCTTACCGAAGGACCTGGAAGAACGACTGGCCCGCGTGGCGAAGGGAACCGGGCGCCCGAAGAG
TCACTATCTACGCTCGCTACTGGAAGAGAACATCGAGCGGCTGGAATGGGAGGCCAAGCTGGAGGAGAAGGTCGCCGACA
TTCGGGCCGGTCGCCGCCGGACCTACTCTCTGGACGAAGTAGAGGCAGAGCTTGACCTGGCAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References