Detailed information of TA system TA063097

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-pasA/RelE-HTH
• Location: 188679..189153
• Replicon: chromosome
• Accession: NZ_CP015449
• Organism: Dietzia lutea strain YIM 80766

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: A6035_RS00805
• Protein ID: WP_108846222.1
• Coordinates: 188679..188942 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: A6035_RS00810
• Protein ID: WP_108848990.1
• Coordinates: 188926..189153 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A6035_RS00790	184704..185735	-	1032	WP_159149555.1	hypothetical protein	-
A6035_RS00795	186373..186651	-	279	WP_108846220.1	WhiB family transcriptional regulator	-
A6035_RS00800	187237..188391	-	1155	WP_108846221.1	hypothetical protein	-
A6035_RS00805	188679..188942	-	264	WP_108846222.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
A6035_RS00810	188926..189153	-	228	WP_108848990.1	ribbon-helix-helix protein, CopG family	Antitoxin
A6035_RS00815	189326..190306	-	981	WP_108846223.1	cation transporter	-
A6035_RS00820	190439..190918	-	480	WP_200836386.1	transporter substrate-binding domain-containing protein	-
A6035_RS00825	191113..191531	-	419	Protein_162	ChaB family protein	-
A6035_RS00830	191887..192138	-	252	WP_108848992.1	acyl carrier protein	-
A6035_RS00835	192450..192803	+	354	WP_108846224.1	hypothetical protein	-
A6035_RS00840	192800..193591	+	792	WP_108846225.1	NAD(P)H-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-86)

Antitoxin

• Protein of unknown function DUF6290 (1-71)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10186.80 Da
• Isoelectric Point: 9.5967

>T63097 WP_108846222.1 NZ_CP015449:c188942-188679 [Dietzia lutea]
MTWQIELDDDARKALRKLDKPTAQRIVKKLREVEALADPTDMGKPLTANRAGFWVYRVGDYRLVCDIQFGRLVVLVIEVQ
HRSENYR

Nucleotide

• Length: 264 bp

>T63097 NZ_CP015449:c188942-188679 [Dietzia lutea]
TTGACCTGGCAGATTGAGCTAGACGATGACGCCCGCAAGGCGTTACGCAAGCTCGACAAACCCACCGCCCAGCGGATCGT
CAAAAAGCTCAGAGAAGTAGAGGCCCTCGCCGACCCGACCGACATGGGCAAGCCGCTGACGGCGAACCGAGCCGGGTTCT
GGGTCTACCGCGTGGGCGACTACCGCCTGGTCTGCGACATTCAGTTCGGCCGACTAGTCGTACTTGTTATCGAGGTCCAA
CATCGCAGCGAAAACTACCGCTGA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 8737.90 Da
• Isoelectric Point: 5.2375

>AT63097 WP_108848990.1 NZ_CP015449:c189153-188926 [Dietzia lutea]
MTTTVRLPKDLEERLARVAKGTGRPKSHYLRSLLEENIERLEWEAKLEEKVADIRAGRRRTYSLDEVEAELDLAD

Nucleotide

• Length: 228 bp

>AT63097 NZ_CP015449:c189153-188926 [Dietzia lutea]
ATGACCACAACAGTTCGCTTACCGAAGGACCTGGAAGAACGACTGGCCCGCGTGGCGAAGGGAACCGGGCGCCCGAAGAG
TCACTATCTACGCTCGCTACTGGAAGAGAACATCGAGCGGCTGGAATGGGAGGCCAAGCTGGAGGAGAAGGTCGCCGACA
TTCGGGCCGGTCGCCGCCGGACCTACTCTCTGGACGAAGTAGAGGCAGAGCTTGACCTGGCAGATTGA