Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 1373933..1374740 Replicon chromosome
Accession NZ_CP015436
Organism Anoxybacillus sp. B7M1

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag GFC29_RS06460 Protein ID WP_044741982.1
Coordinates 1374330..1374740 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag GFC29_RS06455 Protein ID WP_156487495.1
Coordinates 1373933..1374340 (+) Length 136 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GFC29_RS06440 1370417..1371163 - 747 WP_044741986.1 hypothetical protein -
GFC29_RS06445 1371160..1372659 - 1500 WP_052660919.1 hypothetical protein -
GFC29_RS06450 1372647..1373663 - 1017 WP_044741984.1 hypothetical protein -
GFC29_RS06455 1373933..1374340 + 408 WP_156487495.1 nucleotidyltransferase domain-containing protein Antitoxin
GFC29_RS06460 1374330..1374740 + 411 WP_044741982.1 DUF86 domain-containing protein Toxin
GFC29_RS19045 1374762..1374932 - 171 Protein_1304 transposase -
GFC29_RS06465 1375069..1377207 - 2139 WP_044741981.1 DEAD/DEAH box helicase -
GFC29_RS06470 1377210..1378538 - 1329 WP_044741980.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(14-131)

Antitoxin

Polymerase beta, nucleotidyltransferase

(9-99)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15889.42 Da        Isoelectric Point: 7.0499

>T63071 WP_044741982.1 NZ_CP015436:1374330-1374740 [Anoxybacillus sp. B7M1]
MKNDVILNKISVIERCIKRIHEEYENNPKNLENYTKQDSMILNLQRACEASIDLAMHMVAQKKLGLPQNSRDAFSLLEQH
GIITPFLSQKMKAMVGFRNIAVHDYQEINLTILQKILDHHLTDFTEFTKAILFYEQ

Download         Length: 411 bp

>T63071 NZ_CP015436:1374330-1374740 [Anoxybacillus sp. B7M1]
ATGAAAAATGATGTCATTTTAAATAAAATTAGCGTGATCGAGCGGTGCATAAAGCGCATTCACGAAGAATATGAGAACAA
CCCGAAAAATTTAGAAAACTACACGAAGCAAGACTCCATGATCTTAAATCTCCAACGAGCATGTGAAGCAAGCATCGACC
TGGCGATGCACATGGTCGCACAGAAAAAGCTAGGCCTCCCCCAAAACAGTCGAGACGCTTTTTCTCTTTTAGAACAGCAC
GGCATCATCACTCCTTTTCTTTCACAAAAAATGAAAGCGATGGTCGGATTTAGAAACATCGCTGTTCACGACTACCAGGA
GATTAATTTGACAATTTTGCAAAAAATACTTGATCACCATCTAACCGACTTTACCGAGTTCACGAAAGCGATTCTTTTTT
ATGAACAGTGA

Antitoxin


Download         Length: 136 a.a.        Molecular weight: 15629.69 Da        Isoelectric Point: 4.6889

>AT63071 WP_156487495.1 NZ_CP015436:1373933-1374340 [Anoxybacillus sp. B7M1]
MTEQIEPIIIEVLTETVSPYLIYLFGSTVTGHVHQDSDIDIAFLSDQKQLDHYERFMVAQELASKLHRDVDLVDLKQAST
VFQAQVVSNGKVIYCTNEQKKAEYEWRALKMYAKLNEERTEILRNINESGSVYEK

Download         Length: 408 bp

>AT63071 NZ_CP015436:1373933-1374340 [Anoxybacillus sp. B7M1]
TTGACGGAACAGATCGAGCCAATCATTATTGAAGTGTTGACCGAAACGGTGTCCCCATACTTGATTTATTTGTTTGGATC
AACGGTTACAGGACATGTTCATCAAGACAGCGACATTGATATCGCTTTTCTCAGCGACCAAAAACAATTGGATCATTATG
AACGATTTATGGTTGCGCAAGAATTGGCATCCAAACTGCACCGGGACGTCGATCTTGTGGACCTCAAACAAGCAAGCACT
GTGTTTCAAGCACAAGTGGTCAGTAATGGCAAAGTCATCTATTGTACAAATGAACAGAAAAAAGCCGAATATGAATGGAG
AGCCTTGAAGATGTACGCAAAATTGAATGAAGAACGCACGGAAATCTTGCGAAACATTAATGAAAGCGGGTCGGTTTATG
AAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References