Detailed information of TA system TA063071

Bioinformatically predicted

Overview

TA module

• Type: VII
• Classification (family/domain): HepT-MntA/HepT(toxin)
• Location: 1373933..1374740
• Replicon: chromosome
• Accession: NZ_CP015436
• Organism: Anoxybacillus sp. B7M1

Toxin (Protein)

• Gene name: hepT
• Uniprot ID: -
• Locus tag: GFC29_RS06460
• Protein ID: WP_044741982.1
• Coordinates: 1374330..1374740 (+)
• Length: 137 a.a.

Antitoxin (Protein)

• Gene name: mntA
• Uniprot ID: -
• Locus tag: GFC29_RS06455
• Protein ID: WP_156487495.1
• Coordinates: 1373933..1374340 (+)
• Length: 136 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GFC29_RS06440	1370417..1371163	-	747	WP_044741986.1	hypothetical protein	-
GFC29_RS06445	1371160..1372659	-	1500	WP_052660919.1	hypothetical protein	-
GFC29_RS06450	1372647..1373663	-	1017	WP_044741984.1	hypothetical protein	-
GFC29_RS06455	1373933..1374340	+	408	WP_156487495.1	nucleotidyltransferase domain-containing protein	Antitoxin
GFC29_RS06460	1374330..1374740	+	411	WP_044741982.1	DUF86 domain-containing protein	Toxin
GFC29_RS19045	1374762..1374932	-	171	Protein_1304	transposase	-
GFC29_RS06465	1375069..1377207	-	2139	WP_044741981.1	DEAD/DEAH box helicase	-
GFC29_RS06470	1377210..1378538	-	1329	WP_044741980.1	ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease HepT-like (14-131)

Antitoxin

• Polymerase beta, nucleotidyltransferase (9-99)

Sequences

Toxin

Protein

• Length: 137 a.a.
• Molecular weight: 15889.42 Da
• Isoelectric Point: 7.0499

>T63071 WP_044741982.1 NZ_CP015436:1374330-1374740 [Anoxybacillus sp. B7M1]
MKNDVILNKISVIERCIKRIHEEYENNPKNLENYTKQDSMILNLQRACEASIDLAMHMVAQKKLGLPQNSRDAFSLLEQH
GIITPFLSQKMKAMVGFRNIAVHDYQEINLTILQKILDHHLTDFTEFTKAILFYEQ

Nucleotide

• Length: 411 bp

>T63071 NZ_CP015436:1374330-1374740 [Anoxybacillus sp. B7M1]
ATGAAAAATGATGTCATTTTAAATAAAATTAGCGTGATCGAGCGGTGCATAAAGCGCATTCACGAAGAATATGAGAACAA
CCCGAAAAATTTAGAAAACTACACGAAGCAAGACTCCATGATCTTAAATCTCCAACGAGCATGTGAAGCAAGCATCGACC
TGGCGATGCACATGGTCGCACAGAAAAAGCTAGGCCTCCCCCAAAACAGTCGAGACGCTTTTTCTCTTTTAGAACAGCAC
GGCATCATCACTCCTTTTCTTTCACAAAAAATGAAAGCGATGGTCGGATTTAGAAACATCGCTGTTCACGACTACCAGGA
GATTAATTTGACAATTTTGCAAAAAATACTTGATCACCATCTAACCGACTTTACCGAGTTCACGAAAGCGATTCTTTTTT
ATGAACAGTGA

Antitoxin

Protein

• Length: 136 a.a.
• Molecular weight: 15629.69 Da
• Isoelectric Point: 4.6889

>AT63071 WP_156487495.1 NZ_CP015436:1373933-1374340 [Anoxybacillus sp. B7M1]
MTEQIEPIIIEVLTETVSPYLIYLFGSTVTGHVHQDSDIDIAFLSDQKQLDHYERFMVAQELASKLHRDVDLVDLKQAST
VFQAQVVSNGKVIYCTNEQKKAEYEWRALKMYAKLNEERTEILRNINESGSVYEK

Nucleotide

• Length: 408 bp

>AT63071 NZ_CP015436:1373933-1374340 [Anoxybacillus sp. B7M1]
TTGACGGAACAGATCGAGCCAATCATTATTGAAGTGTTGACCGAAACGGTGTCCCCATACTTGATTTATTTGTTTGGATC
AACGGTTACAGGACATGTTCATCAAGACAGCGACATTGATATCGCTTTTCTCAGCGACCAAAAACAATTGGATCATTATG
AACGATTTATGGTTGCGCAAGAATTGGCATCCAAACTGCACCGGGACGTCGATCTTGTGGACCTCAAACAAGCAAGCACT
GTGTTTCAAGCACAAGTGGTCAGTAATGGCAAAGTCATCTATTGTACAAATGAACAGAAAAAAGCCGAATATGAATGGAG
AGCCTTGAAGATGTACGCAAAATTGAATGAAGAACGCACGGAAATCTTGCGAAACATTAATGAAAGCGGGTCGGTTTATG
AAAAATGA