Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 732932..733519 Replicon chromosome
Accession NZ_CP015421
Organism Rhodovulum sulfidophilum strain SNK001

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag A6024_RS03655 Protein ID WP_042464486.1
Coordinates 733229..733519 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag A6024_RS03650 Protein ID WP_042458069.1
Coordinates 732932..733219 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6024_RS03635 728418..729107 + 690 WP_042458062.1 hypothetical protein -
A6024_RS20815 729351..732215 - 2865 WP_063490869.1 pentapeptide repeat-containing protein -
A6024_RS03650 732932..733219 - 288 WP_042458069.1 putative addiction module antidote protein Antitoxin
A6024_RS03655 733229..733519 - 291 WP_042464486.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A6024_RS03660 733899..734705 + 807 WP_155734706.1 HNH endonuclease -
A6024_RS20820 735071..735223 + 153 WP_168161804.1 hypothetical protein -
A6024_RS03670 735223..736491 + 1269 WP_042458072.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
A6024_RS03675 736488..736964 + 477 WP_042458075.1 DUF2948 family protein -
A6024_RS03680 737050..738360 + 1311 WP_042458078.1 histidinol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 718657..735223 16566


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10994.80 Da        Isoelectric Point: 10.2250

>T63063 WP_042464486.1 NZ_CP015421:c733519-733229 [Rhodovulum sulfidophilum]
MRYEIHQSAEFSKWLRKLKDRTAQARIAIRIARLEAGLMGDAKFFDGIGELRITYGPGYRVYFVQQGETIIILLCGGDKG
SQRRDIEKAKTMAKEL

Download         Length: 291 bp

>T63063 NZ_CP015421:c733519-733229 [Rhodovulum sulfidophilum]
ATGCGTTACGAAATTCACCAGTCCGCCGAGTTCTCGAAATGGCTTCGCAAGCTGAAAGACCGCACGGCGCAAGCCCGCAT
CGCGATCAGGATCGCCCGGCTTGAAGCTGGCCTCATGGGCGACGCCAAGTTCTTCGACGGCATCGGTGAACTTCGGATCA
CCTACGGCCCGGGATACCGCGTCTACTTCGTCCAGCAGGGCGAGACGATCATCATCCTGCTCTGCGGCGGCGACAAAGGC
TCCCAGCGCCGGGACATCGAAAAGGCCAAGACCATGGCCAAGGAACTTTAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10051.47 Da        Isoelectric Point: 5.6939

>AT63063 WP_042458069.1 NZ_CP015421:c733219-732932 [Rhodovulum sulfidophilum]
MPIETTRFDAAEYLDTPEAQAMLLSDAFETGDAAYIKHAIGIVARARGIKDTAEAAGITREALHRALGEKGNPRLSTILG
VTRALGLTLKVEASA

Download         Length: 288 bp

>AT63063 NZ_CP015421:c733219-732932 [Rhodovulum sulfidophilum]
ATGCCTATCGAAACTACCCGCTTCGACGCGGCCGAATATCTCGACACGCCGGAAGCGCAAGCCATGCTGCTCTCCGACGC
CTTCGAGACGGGTGACGCCGCCTACATCAAGCACGCCATCGGGATCGTCGCCAGGGCGCGCGGGATCAAGGACACGGCCG
AGGCCGCCGGGATCACGCGGGAGGCGCTGCACCGCGCCTTGGGTGAGAAGGGAAACCCGAGGCTGTCTACTATCCTCGGC
GTGACCAGGGCACTCGGGCTGACCTTGAAGGTCGAGGCGTCGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References