Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2132607..2132752 Replicon chromosome
Accession NZ_CP015392
Organism Klebsiella pneumoniae strain CR14

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2132643..2132745 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2132607..2132752 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6P37_RS10560 2127737..2129797 + 2061 WP_004151449.1 oligopeptidase B -
A6P37_RS10565 2129801..2130460 - 660 WP_002911407.1 exodeoxyribonuclease X -
A6P37_RS10570 2130539..2130769 - 231 WP_002911406.1 DNA polymerase III subunit theta -
A6P37_RS10575 2130882..2131256 + 375 WP_004151448.1 CopC domain-containing protein YobA -
A6P37_RS10580 2131260..2132129 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
A6P37_RS10585 2132146..2132484 + 339 WP_002911404.1 YebY family protein -
- 2132607..2132752 - 146 - - Antitoxin
- 2132643..2132745 + 103 - - Toxin
A6P37_RS31175 2133120..2133263 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
A6P37_RS10595 2133368..2134336 - 969 WP_004151446.1 VirK/YbjX family protein -
A6P37_RS10600 2134493..2135146 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
A6P37_RS10605 2135143..2135334 - 192 WP_002911395.1 YebW family protein -
A6P37_RS10610 2135432..2135671 - 240 WP_002911393.1 YebV family protein -
A6P37_RS10615 2135787..2137220 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T63020 NZ_CP015392:2132643-2132745 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT63020 NZ_CP015392:c2132752-2132607 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References