Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1918392..1918537 Replicon chromosome
Accession NZ_CP015382
Organism Klebsiella pneumoniae strain CN1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1918428..1918530 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1918392..1918537 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A6U99_RS09750 1913522..1915582 + 2061 WP_004151449.1 oligopeptidase B -
A6U99_RS09760 1915586..1916245 - 660 WP_002911407.1 exodeoxyribonuclease X -
A6U99_RS09765 1916324..1916554 - 231 WP_002911406.1 DNA polymerase III subunit theta -
A6U99_RS09770 1916667..1917041 + 375 WP_004151448.1 CopC domain-containing protein YobA -
A6U99_RS09775 1917045..1917914 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
A6U99_RS09780 1917931..1918269 + 339 WP_002911404.1 YebY family protein -
- 1918392..1918537 - 146 - - Antitoxin
- 1918428..1918530 + 103 - - Toxin
A6U99_RS28870 1918905..1919048 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
A6U99_RS09795 1919153..1920121 - 969 WP_014907334.1 VirK/YbjX family protein -
A6U99_RS09800 1920278..1920931 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
A6U99_RS09805 1920928..1921119 - 192 WP_002911395.1 YebW family protein -
A6U99_RS09810 1921217..1921456 - 240 WP_002911393.1 YebV family protein -
A6U99_RS09815 1921572..1923005 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T62977 NZ_CP015382:1918428-1918530 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT62977 NZ_CP015382:c1918537-1918392 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References