Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | omega-epsilon-zeta/- |
| Location | 4182211..4183790 | Replicon | chromosome |
| Accession | NC_017267 | ||
| Organism | Xanthomonas oryzae pv. oryzicola BLS256 | ||
Toxin (Protein)
| Gene name | avrRxo1 | Uniprot ID | - |
| Locus tag | XOC_RS18065 | Protein ID | Protein_3555 |
| Coordinates | 4182530..4183879 (-) | Length | 450 a.a. |
Antitoxin (Protein)
| Gene name | arc1 | Uniprot ID | Q6TKR9 |
| Locus tag | XOC_RS18060 | Protein ID | WP_041183485.1 |
| Coordinates | 4182216..4182512 (-) | Length | 99 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| XOC_RS18045 | 4178079..4178903 | - | 825 | Protein_3550 | IS30-like element IS1112a family transposase | - |
| XOC_RS18050 | 4178925..4180301 | - | 1377 | WP_041183484.1 | IS5 family transposase | - |
| XOC_RS18055 (XOC_4047) | 4180351..4181727 | - | 1377 | WP_082352891.1 | IS5 family transposase | - |
| XOC_RS23785 | 4181843..4181980 | - | 138 | Protein_3553 | helix-turn-helix domain-containing protein | - |
| XOC_RS18060 (XOC_4047a) | 4182216..4182512 | - | 297 | WP_041183485.1 | hypothetical protein | Antitoxin |
| XOC_RS18065 (XOC_4048) | 4182530..4183879 | - | 1350 | Protein_3555 | avirulence protein | Toxin |
| XOC_RS18070 (XOC_4049) | 4184175..4185551 | - | 1377 | WP_082352919.1 | IS5 family transposase | - |
| XOC_RS18075 | 4185694..4187070 | - | 1377 | WP_041183486.1 | IS5 family transposase | - |
| XOC_RS18080 (XOC_4051) | 4187120..4188496 | - | 1377 | WP_041183487.1 | IS5-like element ISXo4 family transposase | - |
| XOC_RS25120 (XOC_4052) | 4188580..4188729 | + | 150 | WP_153296776.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | IScluster/Tn | - | - | 4173890..4190318 | 16428 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 450 a.a. Molecular weight: 48393.62 Da Isoelectric Point: 7.4806
>T6288 Protein_3555 NC_017267:c4183879-4182530 [Xanthomonas oryzae pv. oryzicola BLS256]
VRVAIRIALNVCRVRHTCIALDFHLFNMKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPA
GPKSSNTTDAYIHESLPHSVPIAGASTSAVTHQQATQRKGTDEIYGLGSLPSAGPGRWEYLANPGNWHPERRKLHEKLLD
QARSSALTLAESLESDGCQPTLFALRGNTATGKTRIATKKIPVLAAALKKTAGKGCVNPDVFKSSLAKSETGAKIFSSAQ
VHSESSFLADRFEGGLRSQKTGSGAIASIVVDKRLSREYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGED
PRPPYPVVSSGFVAVRSNRMYVIDRFIADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTGDLA
DKVIDKELIDRLENNIADPERAAKTRAALEKYSGKSWSAALAAHSELI
VRVAIRIALNVCRVRHTCIALDFHLFNMKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPA
GPKSSNTTDAYIHESLPHSVPIAGASTSAVTHQQATQRKGTDEIYGLGSLPSAGPGRWEYLANPGNWHPERRKLHEKLLD
QARSSALTLAESLESDGCQPTLFALRGNTATGKTRIATKKIPVLAAALKKTAGKGCVNPDVFKSSLAKSETGAKIFSSAQ
VHSESSFLADRFEGGLRSQKTGSGAIASIVVDKRLSREYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGED
PRPPYPVVSSGFVAVRSNRMYVIDRFIADPSLGNYRLFGTAEDGEKVMVASVIGGEFSVENAELYEKITSPQLSVTGDLA
DKVIDKELIDRLENNIADPERAAKTRAALEKYSGKSWSAALAAHSELI
Download Length: 1350 bp
>T6288 NC_017267:c4183879-4182530 [Xanthomonas oryzae pv. oryzicola BLS256]
GTGCGAGTTGCGATTCGAATCGCTCTTAATGTTTGCAGGGTCAGGCACACCTGTATTGCATTGGACTTTTGACATCTTTT
TAACATGAAAAACAAGACAGACATTGCTGGCATAGCCGGACTTTCTACGTCTCATGTTTCCTTTGATGACGCAGAATCCA
AAAGCGTCCTAGATGGATCAACACAGTCTACGCCGGAGTACAAATTCCAGACCCCGCTTGATCAGTTGCCGGCTAGGCCC
GCTGGTCCGAAGAGCAGTAACACAACTGATGCTTACATTCATGAATCACTGCCGCATTCGGTTCCAATCGCAGGTGCATC
GACCTCCGCGGTGACACATCAACAGGCTACTCAGCGTAAAGGCACCGATGAGATCTATGGTTTGGGCAGCCTCCCATCTG
CTGGTCCAGGGCGATGGGAGTATCTTGCGAATCCGGGGAACTGGCATCCCGAGCGCCGTAAGTTACACGAAAAGCTATTA
GATCAAGCGCGATCTTCTGCCTTGACCCTGGCAGAATCCCTTGAGAGTGATGGCTGCCAACCGACATTGTTTGCGCTGCG
CGGAAATACCGCAACGGGTAAAACACGGATTGCGACAAAAAAGATCCCGGTGCTCGCAGCAGCTCTGAAGAAGACAGCTG
GGAAAGGTTGCGTGAATCCAGATGTATTCAAGAGTTCGCTTGCGAAATCCGAGACAGGCGCCAAGATATTTAGTTCGGCA
CAAGTGCATAGCGAGTCATCTTTTCTTGCCGACCGGTTTGAAGGCGGACTTCGCTCTCAAAAGACGGGCAGCGGTGCAAT
CGCTAGCATTGTTGTCGACAAGCGCTTGTCAAGAGAGTACGAAATTGATAGCTACATACAACTAGCGAAAGAAACCGGTA
GAAAAGTGGAATTGTGCGATATCGACGCGCCCCTAGAGAATTCTTTGGTGGGAGTTTTGCAGCGAAAACCGGAAGGTGAA
GATCCTAGGCCTCCGTACCCTGTAGTCTCGAGTGGATTTGTAGCCGTACGGAGCAATAGAATGTACGTGATAGACAGGTT
CATTGCCGATCCGAGCCTGGGAAACTACCGACTATTCGGAACAGCTGAAGATGGTGAGAAGGTCATGGTTGCTAGCGTGA
TTGGCGGTGAGTTTAGTGTAGAGAATGCTGAGTTGTATGAAAAAATCACGTCCCCACAGCTCTCGGTTACGGGCGATTTG
GCTGATAAGGTAATCGACAAGGAATTGATTGATCGTCTGGAAAATAATATAGCTGACCCCGAGCGGGCGGCCAAGACGCG
AGCCGCCCTGGAAAAATACAGCGGTAAGTCATGGTCGGCCGCGCTAGCTGCTCACAGCGAGCTAATTTGA
GTGCGAGTTGCGATTCGAATCGCTCTTAATGTTTGCAGGGTCAGGCACACCTGTATTGCATTGGACTTTTGACATCTTTT
TAACATGAAAAACAAGACAGACATTGCTGGCATAGCCGGACTTTCTACGTCTCATGTTTCCTTTGATGACGCAGAATCCA
AAAGCGTCCTAGATGGATCAACACAGTCTACGCCGGAGTACAAATTCCAGACCCCGCTTGATCAGTTGCCGGCTAGGCCC
GCTGGTCCGAAGAGCAGTAACACAACTGATGCTTACATTCATGAATCACTGCCGCATTCGGTTCCAATCGCAGGTGCATC
GACCTCCGCGGTGACACATCAACAGGCTACTCAGCGTAAAGGCACCGATGAGATCTATGGTTTGGGCAGCCTCCCATCTG
CTGGTCCAGGGCGATGGGAGTATCTTGCGAATCCGGGGAACTGGCATCCCGAGCGCCGTAAGTTACACGAAAAGCTATTA
GATCAAGCGCGATCTTCTGCCTTGACCCTGGCAGAATCCCTTGAGAGTGATGGCTGCCAACCGACATTGTTTGCGCTGCG
CGGAAATACCGCAACGGGTAAAACACGGATTGCGACAAAAAAGATCCCGGTGCTCGCAGCAGCTCTGAAGAAGACAGCTG
GGAAAGGTTGCGTGAATCCAGATGTATTCAAGAGTTCGCTTGCGAAATCCGAGACAGGCGCCAAGATATTTAGTTCGGCA
CAAGTGCATAGCGAGTCATCTTTTCTTGCCGACCGGTTTGAAGGCGGACTTCGCTCTCAAAAGACGGGCAGCGGTGCAAT
CGCTAGCATTGTTGTCGACAAGCGCTTGTCAAGAGAGTACGAAATTGATAGCTACATACAACTAGCGAAAGAAACCGGTA
GAAAAGTGGAATTGTGCGATATCGACGCGCCCCTAGAGAATTCTTTGGTGGGAGTTTTGCAGCGAAAACCGGAAGGTGAA
GATCCTAGGCCTCCGTACCCTGTAGTCTCGAGTGGATTTGTAGCCGTACGGAGCAATAGAATGTACGTGATAGACAGGTT
CATTGCCGATCCGAGCCTGGGAAACTACCGACTATTCGGAACAGCTGAAGATGGTGAGAAGGTCATGGTTGCTAGCGTGA
TTGGCGGTGAGTTTAGTGTAGAGAATGCTGAGTTGTATGAAAAAATCACGTCCCCACAGCTCTCGGTTACGGGCGATTTG
GCTGATAAGGTAATCGACAAGGAATTGATTGATCGTCTGGAAAATAATATAGCTGACCCCGAGCGGGCGGCCAAGACGCG
AGCCGCCCTGGAAAAATACAGCGGTAAGTCATGGTCGGCCGCGCTAGCTGCTCACAGCGAGCTAATTTGA
Antitoxin
Download Length: 99 a.a. Molecular weight: 11364.89 Da Isoelectric Point: 4.9649
>AT6288 WP_041183485.1 NC_017267:c4182512-4182216 [Xanthomonas oryzae pv. oryzicola BLS256]
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERNDIYERMYYVEYPN
VMTLKEFAHIVETLFSWS
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERNDIYERMYYVEYPN
VMTLKEFAHIVETLFSWS
Download Length: 297 bp
>AT6288 NC_017267:c4182512-4182216 [Xanthomonas oryzae pv. oryzicola BLS256]
ATGAAAACTTTGACAGGCGCAGACGCACTCGAATTTCATAAGAAGCTTAAGGAACGCAATAAAGCCTTACATGCTTCCGA
CCTCGAGTTAGCACTGGTGCACGCCGATGCTGTCGGCAAAGAACGGTTCGATCTCGAGGAGCTGGAGAAAATTTGCGATA
CCAGCGATGCGGGGCGCCTTACTGATGCGAAAGAGCGAAACGACATATATGAACGGATGTACTACGTTGAGTATCCCAAC
GTTATGACGTTAAAGGAATTCGCTCATATCGTCGAGACACTTTTCTCGTGGTCATGA
ATGAAAACTTTGACAGGCGCAGACGCACTCGAATTTCATAAGAAGCTTAAGGAACGCAATAAAGCCTTACATGCTTCCGA
CCTCGAGTTAGCACTGGTGCACGCCGATGCTGTCGGCAAAGAACGGTTCGATCTCGAGGAGCTGGAGAAAATTTGCGATA
CCAGCGATGCGGGGCGCCTTACTGATGCGAAAGAGCGAAACGACATATATGAACGGATGTACTACGTTGAGTATCCCAAC
GTTATGACGTTAAAGGAATTCGCTCATATCGTCGAGACACTTTTCTCGTGGTCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
References
(1) Lindsay R Triplett et al. (2016) AvrRxo1 Is a Bifunctional Type III Secreted Effector and Toxin-Antitoxin System Component with Homologs in Diverse Environmental Contexts. PloS One 11(7):e0158856. [PubMed:27391081]