Detailed information of TA system TA062864

Bioinformatically predicted

Overview

TA module

• Type: III
• Classification (family/domain): tenpIN/-
• Location: 5645826..5646365
• Replicon: chromosome
• Accession: NZ_CP015281
• Organism: Photorhabdus laumondii subsp. laumondii strain DSPV002N

Toxin (Protein)

• Gene name: tenpN
• Uniprot ID: Q7MY23
• Locus tag: A4R40_RS25075
• Protein ID: WP_011148929.1
• Coordinates: 5645826..5646257 (-)
• Length: 144 a.a.

Antitoxin (RNA)

Gene name	tenpI
Locus tag	-
Coordinates	5646316..5646365 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A4R40_RS25050	5641322..5641780	+	459	WP_011148924.1	dUTP diphosphatase	-
A4R40_RS25055	5642021..5642620	+	600	WP_011148925.1	nucleoid occlusion factor SlmA	-
A4R40_RS25060	5642680..5643321	-	642	WP_011148926.1	orotate phosphoribosyltransferase	-
A4R40_RS25065	5643406..5644134	-	729	WP_011148927.1	ribonuclease PH	-
A4R40_RS25070	5644261..5645124	+	864	WP_011148928.1	YicC family protein	-
A4R40_RS25075	5645826..5646257	-	432	WP_011148929.1	hypothetical protein	Toxin
-	5646316..5646365	-	50	NuclAT_1	-	Antitoxin
-	5646316..5646365	-	50	NuclAT_1	-	Antitoxin
-	5646316..5646365	-	50	NuclAT_1	-	Antitoxin
-	5646316..5646365	-	50	NuclAT_1	-	Antitoxin
-	5646366..5646415	-	50	NuclAT_0	-	-
-	5646366..5646415	-	50	NuclAT_0	-	-
-	5646366..5646415	-	50	NuclAT_0	-	-
-	5646366..5646415	-	50	NuclAT_0	-	-
A4R40_RS25080	5646485..5646679	-	195	WP_011148930.1	hypothetical protein	-
A4R40_RS25085	5647315..5648349	+	1035	WP_071824185.1	reverse transcriptase family protein	-
A4R40_RS25090	5648339..5649000	+	662	Protein_4789	retron Ec48 family effector membrane protein	-
A4R40_RS25105	5649578..5650528	-	951	WP_011148935.1	hypothetical protein	-
A4R40_RS25110	5650805..5650888	+	84	WP_071824186.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 144 a.a.
• Molecular weight: 16736.27 Da
• Isoelectric Point: 8.2240

>T62864 WP_011148929.1 NZ_CP015281:c5646257-5645826 [Photorhabdus laumondii subsp. laumondii]
MILRQIKQDVYNRLCENRPQVLEKNRGYGVISITLNGLTFAVPLRSNLNHPNGFKTIFIKEKKCWSGLDYSKALLIDVDD
LEPQAFKLKMEKEYEKLKANEKKIEVEFGAYVQGYIEYINTGEGDDRCYKFTTLQYFHRDLGL

Nucleotide

• Length: 432 bp

>T62864 NZ_CP015281:c5646257-5645826 [Photorhabdus laumondii subsp. laumondii]
ATGATATTGCGCCAGATCAAACAAGATGTCTACAACAGGCTTTGTGAAAATAGACCGCAAGTTTTAGAAAAAAATAGGGG
GTATGGCGTTATATCGATTACTTTAAACGGACTTACATTCGCAGTCCCTTTACGAAGTAATCTAAATCATCCTAATGGGT
TCAAGACTATCTTCATAAAGGAAAAAAAATGCTGGAGTGGCTTAGATTACTCAAAAGCTTTACTCATTGATGTTGATGAT
CTAGAACCACAAGCTTTTAAGCTAAAAATGGAAAAAGAGTATGAAAAGTTAAAAGCAAACGAAAAAAAGATCGAGGTGGA
ATTTGGGGCTTATGTTCAAGGATACATTGAATACATAAATACTGGTGAGGGTGATGATCGTTGTTATAAATTTACTACAC
TCCAGTATTTCCATAGAGATTTGGGCTTATAG

Antitoxin

Nucleotide

• Length: 50 bp

>AT62864 NZ_CP015281:c5646365-5646316 [Photorhabdus laumondii subsp. laumondii]
GATTATGTGGCGGTAGAGGCATCCCCACGTTAAATAGAACAACCTCATTG

Structures

Toxin

• AlphaFold DB: A0A6L9JUM7

Antitoxin