Detailed information of TA system TA062843

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 2662394..2662929
• Replicon: chromosome
• Accession: NZ_CP015281
• Organism: Photorhabdus laumondii subsp. laumondii strain DSPV002N

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: A4R40_RS11705
• Protein ID: WP_109791556.1
• Coordinates: 2662394..2662681 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q7N4Q7
• Locus tag: A4R40_RS11710
• Protein ID: WP_011146514.1
• Coordinates: 2662678..2662929 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A4R40_RS11695	2657677..2661123	-	3447	WP_109791554.1	molybdopterin-dependent oxidoreductase	-
A4R40_RS11700	2661327..2662238	-	912	WP_109791555.1	hypothetical protein	-
A4R40_RS11705	2662394..2662681	-	288	WP_109791556.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
A4R40_RS11710	2662678..2662929	-	252	WP_011146514.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
A4R40_RS11715	2663259..2664179	+	921	WP_011146515.1	alpha/beta hydrolase	-
A4R40_RS11720	2664516..2665475	-	960	WP_109791557.1	hypothetical protein	-
A4R40_RS11725	2666117..2666578	+	462	WP_011146517.1	helix-turn-helix domain-containing protein	-
A4R40_RS11730	2666797..2667087	-	291	WP_011146518.1	type II toxin-antitoxin system RelE/ParE family toxin	-
A4R40_RS11735	2667084..2667362	-	279	WP_011146519.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11209.44 Da
• Isoelectric Point: 10.6904

>T62843 WP_109791556.1 NZ_CP015281:c2662681-2662394 [Photorhabdus laumondii subsp. laumondii]
MIYRVKFREDALKEWKRLDKSVQQQFAKKLKKCCVEPHIPSVKLRGMPNCYKIKLRASGFRLVYEVIDNVLIIVVVAVGK
RERSEAYELASKRLR

Nucleotide

• Length: 288 bp

>T62843 NZ_CP015281:c2662681-2662394 [Photorhabdus laumondii subsp. laumondii]
ATGATCTATAGAGTGAAATTCAGGGAAGATGCACTCAAGGAGTGGAAGAGACTTGATAAATCAGTCCAACAACAATTTGC
TAAGAAGCTGAAAAAGTGCTGTGTTGAACCTCATATTCCATCAGTTAAACTTCGAGGCATGCCGAATTGTTACAAAATAA
AATTACGCGCTTCTGGTTTTCGCTTAGTTTATGAGGTCATAGATAATGTGTTGATTATCGTCGTAGTAGCAGTTGGTAAG
CGCGAACGGAGTGAAGCGTATGAGCTAGCAAGTAAGAGACTAAGATAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9221.57 Da
• Isoelectric Point: 4.0233

>AT62843 WP_011146514.1 NZ_CP015281:c2662929-2662678 [Photorhabdus laumondii subsp. laumondii]
MANIILSDISASISELKKNPMATLSAGAGYPIAILNRNQPVFYCIPAELYEQILDALDDQELIRLVNERRGQALVDVDLD
NYL

Nucleotide

• Length: 252 bp

>AT62843 NZ_CP015281:c2662929-2662678 [Photorhabdus laumondii subsp. laumondii]
ATGGCCAACATAATTCTGTCAGATATTAGCGCAAGCATTAGTGAACTTAAAAAGAACCCTATGGCGACCCTTAGTGCCGG
GGCTGGATACCCTATTGCGATCCTAAATCGTAACCAACCCGTGTTTTATTGTATTCCTGCGGAGCTCTATGAACAGATAC
TTGATGCTTTGGACGATCAAGAGCTTATTCGACTGGTAAATGAGCGTAGAGGGCAGGCATTGGTTGATGTAGATTTGGAT
AATTATCTATGA

Structures

Antitoxin

• AlphaFold DB: A0A6L9JQJ5