Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 143078..143766 Replicon chromosome
Accession NZ_CP015281
Organism Photorhabdus laumondii subsp. laumondii strain DSPV002N

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag A4R40_RS00700 Protein ID WP_011144541.1
Coordinates 143479..143766 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag A4R40_RS00695 Protein ID WP_109791246.1
Coordinates 143078..143404 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A4R40_RS00665 138836..139230 - 395 Protein_127 VOC family protein -
A4R40_RS00670 139425..139592 + 168 WP_082302939.1 DNA alkylation repair protein -
A4R40_RS00675 139636..140232 - 597 WP_011144536.1 hypothetical protein -
A4R40_RS00680 140512..141642 + 1131 WP_109791930.1 ISAs1 family transposase -
A4R40_RS00685 141957..142424 + 468 WP_125043731.1 hypothetical protein -
A4R40_RS00690 142562..143029 + 468 WP_109791245.1 DNA repair protein RadC -
A4R40_RS00695 143078..143404 + 327 WP_109791246.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
A4R40_RS00700 143479..143766 + 288 WP_011144541.1 TA system toxin CbtA family protein Toxin
A4R40_RS00705 143880..144713 + 834 WP_011144542.1 DUF4942 domain-containing protein -
A4R40_RS00710 144801..145838 + 1038 WP_011144543.1 virulence RhuM family protein -
A4R40_RS00715 145968..146102 + 135 Protein_137 virulence RhuM family protein -
A4R40_RS25770 146354..146524 + 171 WP_157852154.1 hypothetical protein -
A4R40_RS00720 146503..147273 - 771 WP_011144544.1 IclR family transcriptional regulator -
A4R40_RS00725 147418..147918 + 501 WP_011144545.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-90)

Antitoxin

Antitoxin CbeA

(7-107)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11027.57 Da        Isoelectric Point: 6.8689

>T62832 WP_011144541.1 NZ_CP015281:143479-143766 [Photorhabdus laumondii subsp. laumondii]
VLVWQTLLTRLLEQHYGLTLNDTPFSDETVIQEHINAGITLADAVNFLVEKYELVRIDLRRFNCQEQSPYLRAVDILRAR
QATGLLRQSHHPSTR

Download         Length: 288 bp

>T62832 NZ_CP015281:143479-143766 [Photorhabdus laumondii subsp. laumondii]
GTGCTTGTCTGGCAAACTCTACTTACACGTCTGCTGGAGCAACATTATGGCCTCACCCTGAATGACACGCCGTTCAGCGA
TGAAACTGTTATTCAGGAACATATCAACGCTGGTATTACATTGGCTGATGCCGTTAACTTTTTGGTAGAAAAGTACGAAC
TGGTTCGTATCGACCTCAGGAGGTTTAACTGTCAGGAGCAATCACCTTATCTTCGGGCTGTAGATATTTTACGGGCAAGG
CAAGCAACCGGCCTTTTGCGGCAAAGCCATCATCCTTCAACTCGCTGA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12532.16 Da        Isoelectric Point: 5.5236

>AT62832 WP_109791246.1 NZ_CP015281:143078-143404 [Photorhabdus laumondii subsp. laumondii]
MEKNDNPEWGLRYDLMPRFTARLVQEGNRLHYLADRAGITGTFNEEECHQLNAAFPHFIKQMELMLLSGELNPRDAHRVT
LYHNELTCEADTLGSCGYVYIAIYPTQR

Download         Length: 327 bp

>AT62832 NZ_CP015281:143078-143404 [Photorhabdus laumondii subsp. laumondii]
ATGGAAAAAAACGATAACCCTGAATGGGGGCTTCGGTACGATTTAATGCCTCGCTTTACCGCAAGGTTAGTACAGGAAGG
CAATCGACTACATTATTTAGCTGACCGCGCCGGGATAACTGGCACTTTCAATGAGGAAGAGTGCCACCAACTGAATGCCG
CATTTCCACACTTTATTAAACAGATGGAGCTGATGCTGCTCTCTGGTGAGCTTAACCCCCGCGATGCACACCGTGTAACG
CTGTACCACAACGAACTGACCTGTGAAGCGGATACGCTCGGTAGCTGTGGCTACGTTTACATCGCTATCTATCCCACTCA
ACGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References