Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2060000..2060271 Replicon chromosome
Accession NZ_CP015244
Organism Escherichia coli O91 str. RM7190

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2060038..2060141 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2060000..2060271 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I51_RS10780 2057157..2058596 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I51_RS10785 2058714..2058950 + 237 WP_001295499.1 DUF1480 family protein -
I51_RS10790 2059055..2059246 + 192 WP_001296140.1 YebW family protein -
I51_RS10795 2059247..2059903 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2060000..2060271 + 272 - - Antitoxin
- 2060038..2060141 - 104 - - Toxin
I51_RS10800 2060299..2060640 - 342 WP_000976492.1 YebY family protein -
I51_RS10805 2060653..2061525 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
I51_RS10810 2061529..2061903 - 375 WP_000204699.1 CopC domain-containing protein YobA -
I51_RS10815 2062042..2062272 + 231 WP_000916763.1 DNA polymerase III subunit theta -
I51_RS10820 2062374..2063030 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
I51_RS10825 2063054..2063716 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T62766 NZ_CP015244:c2060141-2060038 [Escherichia coli O91 str. RM7190]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT62766 NZ_CP015244:2060000-2060271 [Escherichia coli O91 str. RM7190]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References