Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5241215..5241486 Replicon chromosome
Accession NZ_CP015241
Organism Escherichia coli strain 2013C-4465

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5241253..5241356 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5241215..5241486 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A5955_RS26025 5238372..5239811 + 1440 WP_001419087.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
A5955_RS26030 5239929..5240165 + 237 WP_001359800.1 DUF1480 family protein -
A5955_RS26035 5240270..5240461 + 192 WP_001296140.1 YebW family protein -
A5955_RS26040 5240462..5241118 - 657 WP_064032247.1 protein-serine/threonine phosphatase -
- 5241215..5241486 + 272 - - Antitoxin
- 5241253..5241356 - 104 - - Toxin
A5955_RS26050 5241514..5241855 - 342 WP_000976483.1 YebY family protein -
A5955_RS26055 5241868..5242740 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
A5955_RS26060 5242744..5243118 - 375 WP_000168751.1 CopC domain-containing protein YobA -
A5955_RS26065 5243257..5243487 + 231 WP_000916769.1 DNA polymerase III subunit theta -
A5955_RS26070 5243589..5244245 + 657 WP_000011661.1 carbon-nitrogen hydrolase family protein -
A5955_RS26075 5244269..5244931 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T62750 NZ_CP015241:c5241356-5241253 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT62750 NZ_CP015241:5241215-5241486 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References