Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 3444180..3445063 | Replicon | chromosome |
| Accession | NZ_CP015202 | ||
| Organism | Pseudomonas putida B6-2 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A173HDN1 |
| Locus tag | KKK_RS15635 | Protein ID | WP_019751987.1 |
| Coordinates | 3444180..3444617 (-) | Length | 146 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | I7C3Q7 |
| Locus tag | KKK_RS15640 | Protein ID | WP_003250525.1 |
| Coordinates | 3444614..3445063 (-) | Length | 150 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KKK_RS15615 | 3439322..3440386 | + | 1065 | WP_019751984.1 | TerC family protein | - |
| KKK_RS15620 | 3440482..3441711 | - | 1230 | WP_019751985.1 | acyl-CoA dehydrogenase | - |
| KKK_RS15625 | 3441851..3442774 | + | 924 | WP_004573723.1 | LysR family transcriptional regulator | - |
| KKK_RS15630 | 3442968..3444122 | + | 1155 | WP_029380674.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
| KKK_RS15635 | 3444180..3444617 | - | 438 | WP_019751987.1 | RES family NAD+ phosphorylase | Toxin |
| KKK_RS15640 | 3444614..3445063 | - | 450 | WP_003250525.1 | DUF2384 domain-containing protein | Antitoxin |
| KKK_RS15645 | 3445206..3445859 | - | 654 | WP_004573726.1 | oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB | - |
| KKK_RS15650 | 3445963..3446886 | + | 924 | WP_004573727.1 | LysR family transcriptional regulator | - |
| KKK_RS15655 | 3446935..3447765 | + | 831 | WP_019751988.1 | AraC family transcriptional regulator | - |
| KKK_RS15660 | 3447817..3448401 | + | 585 | WP_019751989.1 | LysE family translocator | - |
| KKK_RS15665 | 3448441..3449640 | - | 1200 | WP_014861778.1 | sugar transporter | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 146 a.a. Molecular weight: 15953.22 Da Isoelectric Point: 6.0704
>T62614 WP_019751987.1 NZ_CP015202:c3444617-3444180 [Pseudomonas putida B6-2]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSAHPELTRTLGNRFLDDGSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPPGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSAHPELTRTLGNRFLDDGSALLLPVPSAIMPSTTNYLFNPRHPQAQSAKIQVEDFTPDSRLF
Download Length: 438 bp
>T62614 NZ_CP015202:c3444617-3444180 [Pseudomonas putida B6-2]
GTGATTTTGTGGCGAATCAGCGCCTATGCAGACTTGAGTGGTACGGGGGGCTTGCGTGTAAGTGGCCGCTGGCACCAGGC
GGGGCGGCCGGTGGTGTATGCCGCCACCAGCCCTCCCGGGGCGATGCTGGAAGTGTTGGTACACCTGGAGATCGACCCCG
AGGATTTCCCGACCACCATGCGCTTGCTTCGCATCGAACTGCCCGACACGGTTTCCCAGGCGCAGTTGCCCGCTTTGCAG
CCTGGCTGGTCTGCTCACCCTGAGTTGACCCGTACGCTGGGCAATCGCTTTCTGGATGACGGTTCGGCATTGCTGCTGCC
GGTGCCAAGCGCGATCATGCCCAGCACCACCAATTACCTGTTCAACCCAAGGCACCCGCAGGCGCAGAGCGCGAAAATCC
AGGTTGAGGATTTCACCCCGGACAGCCGCCTGTTCTAG
GTGATTTTGTGGCGAATCAGCGCCTATGCAGACTTGAGTGGTACGGGGGGCTTGCGTGTAAGTGGCCGCTGGCACCAGGC
GGGGCGGCCGGTGGTGTATGCCGCCACCAGCCCTCCCGGGGCGATGCTGGAAGTGTTGGTACACCTGGAGATCGACCCCG
AGGATTTCCCGACCACCATGCGCTTGCTTCGCATCGAACTGCCCGACACGGTTTCCCAGGCGCAGTTGCCCGCTTTGCAG
CCTGGCTGGTCTGCTCACCCTGAGTTGACCCGTACGCTGGGCAATCGCTTTCTGGATGACGGTTCGGCATTGCTGCTGCC
GGTGCCAAGCGCGATCATGCCCAGCACCACCAATTACCTGTTCAACCCAAGGCACCCGCAGGCGCAGAGCGCGAAAATCC
AGGTTGAGGATTTCACCCCGGACAGCCGCCTGTTCTAG
Antitoxin
Download Length: 150 a.a. Molecular weight: 16956.46 Da Isoelectric Point: 5.7258
>AT62614 WP_003250525.1 NZ_CP015202:c3445063-3444614 [Pseudomonas putida B6-2]
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL
MLAEVLRDNGYHEYRARLQALLDIPELASDFEIHTRITDGFAATWLVKLTERGVLTPVERDQIIPLRTLKSRIERDQPLT
VDESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGYGL
Download Length: 450 bp
>AT62614 NZ_CP015202:c3445063-3444614 [Pseudomonas putida B6-2]
ATGCTTGCCGAAGTGCTTCGCGACAACGGTTACCACGAGTACCGGGCGCGCTTGCAGGCGCTGCTGGACATTCCCGAGCT
TGCCAGTGACTTCGAAATCCACACCCGCATCACCGATGGTTTTGCCGCCACCTGGTTGGTAAAGCTGACCGAACGCGGTG
TGCTCACGCCGGTGGAGCGCGACCAGATCATCCCGCTGCGCACCCTCAAATCCCGTATCGAGCGCGACCAACCACTGACC
GTGGATGAGAGCGATCGGCTGTTCCGCTCGGCCCACATCACCGCCATGGCCGAGGCTGTGTTCGGTGAAGCGGGCAAGGC
CAAACGCTGGCTTTCCAAGCCCAAGGAGCGTTTCTCGGGGCTGACGCCGATGCAGATGCTCACCACCCAGCAAGGCACCA
CGCAGGTCGAAGAAATGCTGCTGCAGATTGCCGAGGGCTATGGCCTGTGA
ATGCTTGCCGAAGTGCTTCGCGACAACGGTTACCACGAGTACCGGGCGCGCTTGCAGGCGCTGCTGGACATTCCCGAGCT
TGCCAGTGACTTCGAAATCCACACCCGCATCACCGATGGTTTTGCCGCCACCTGGTTGGTAAAGCTGACCGAACGCGGTG
TGCTCACGCCGGTGGAGCGCGACCAGATCATCCCGCTGCGCACCCTCAAATCCCGTATCGAGCGCGACCAACCACTGACC
GTGGATGAGAGCGATCGGCTGTTCCGCTCGGCCCACATCACCGCCATGGCCGAGGCTGTGTTCGGTGAAGCGGGCAAGGC
CAAACGCTGGCTTTCCAAGCCCAAGGAGCGTTTCTCGGGGCTGACGCCGATGCAGATGCTCACCACCCAGCAAGGCACCA
CGCAGGTCGAAGAAATGCTGCTGCAGATTGCCGAGGGCTATGGCCTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A173HDN1 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | I7C3Q7 |