Detailed information of TA system TA062607

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 4358307..4359070
• Replicon: chromosome
• Accession: NZ_CP015194
• Organism: Shewanella sp. Pdp11

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: A0A2K9A201
• Locus tag: AYJ58_RS19165
• Protein ID: WP_001963894.1
• Coordinates: 4358564..4359070 (+)
• Length: 169 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: A0A2K9A963
• Locus tag: AYJ58_RS19160
• Protein ID: WP_001963895.1
• Coordinates: 4358307..4358573 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AYJ58_RS19140	4353965..4354477	-	513	WP_198555520.1	S26 family signal peptidase	-
AYJ58_RS19145	4354461..4354808	-	348	WP_004249366.1	hypothetical protein	-
AYJ58_RS19150	4354801..4357200	-	2400	WP_106651326.1	type IV secretion system protein TraC	-
AYJ58_RS19155	4357200..4357892	-	693	WP_031500474.1	DsbC family protein	-
AYJ58_RS19160	4358307..4358573	+	267	WP_001963895.1	DUF1778 domain-containing protein	Antitoxin
AYJ58_RS19165	4358564..4359070	+	507	WP_001963894.1	GNAT family N-acetyltransferase	Toxin
AYJ58_RS19170	4359111..4359497	-	387	WP_000180225.1	hypothetical protein	-
AYJ58_RS19175	4359494..4360066	-	573	WP_148039504.1	type IV conjugative transfer system lipoprotein TraV	-
AYJ58_RS19180	4360141..4361430	-	1290	WP_008844783.1	TraB/VirB10 family protein	-
AYJ58_RS19185	4361433..4362329	-	897	WP_106651876.1	type-F conjugative transfer system secretin TraK	-
AYJ58_RS19190	4362313..4362939	-	627	WP_023266689.1	conjugal transfer pilus assembly protein TraE	-
AYJ58_RS19195	4362936..4363217	-	282	WP_000433891.1	type IV conjugative transfer system protein TraL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	adeG	4164169..4402459	238290

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (43-146)

Antitoxin

• Vibrio phage ICP1, Orf50 (8-83)

Sequences

Toxin

Protein

• Length: 169 a.a.
• Molecular weight: 18259.94 Da
• Isoelectric Point: 6.8531

>T62607 WP_001963894.1 NZ_CP015194:4358564-4359070 [Shewanella sp. Pdp11]
MGISAPTLLTDEHEINAFHCGIEELDTWLRKQALKSQKRGTARVYVVNDTDAHQVAGYYAIAMGSVSREQAFSSLRRNSP
DPIPMVILARLGVDNAYQGQGIAAGLLKDCIIRSVQAMNAVGGAGILVHAIDGSAQTFYKKFGFKESTFDPLVLMARICD
IEKSLSID

Nucleotide

• Length: 507 bp

>T62607 NZ_CP015194:4358564-4359070 [Shewanella sp. Pdp11]
TTGGGAATAAGTGCACCAACCCTACTCACTGATGAGCACGAGATTAACGCCTTTCACTGTGGCATTGAAGAACTCGATAC
TTGGTTAAGAAAACAGGCGTTAAAGAGTCAAAAGCGGGGAACCGCGAGAGTGTATGTGGTCAATGACACTGACGCCCATC
AAGTGGCTGGGTACTATGCCATTGCCATGGGATCAGTTTCCAGAGAGCAAGCTTTCAGTTCATTAAGAAGAAATAGCCCA
GATCCCATTCCCATGGTGATTCTAGCCAGGCTTGGAGTAGATAACGCCTATCAAGGTCAAGGCATTGCGGCAGGTCTTTT
AAAAGATTGTATCATTCGCTCAGTACAAGCAATGAACGCTGTCGGTGGCGCAGGTATCTTAGTCCATGCTATTGATGGTA
GTGCGCAAACGTTCTACAAGAAATTTGGCTTCAAAGAATCGACGTTTGATCCTTTAGTACTCATGGCAAGGATCTGCGAT
ATCGAAAAATCATTGTCGATAGACTGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9969.47 Da
• Isoelectric Point: 5.8580

>AT62607 WP_001963895.1 NZ_CP015194:4358307-4358573 [Shewanella sp. Pdp11]
MATKTAPINMRVLPSVRDIIDAAASLKKVDRTVFIQQAALNEAHNVLAEQRDFVLEAKAFEAFDNELRAEPQTLEGMKDL
FKRKAPWE

Nucleotide

• Length: 267 bp

>AT62607 NZ_CP015194:4358307-4358573 [Shewanella sp. Pdp11]
ATGGCTACAAAGACAGCGCCAATCAACATGCGAGTACTGCCATCGGTAAGAGACATTATCGATGCCGCAGCAAGTTTAAA
AAAAGTTGATAGAACCGTATTCATTCAGCAAGCCGCGCTCAATGAAGCGCATAACGTACTGGCCGAACAGCGGGATTTTG
TTCTTGAAGCAAAAGCTTTTGAAGCGTTTGATAACGAACTTCGTGCTGAGCCACAGACTCTTGAAGGCATGAAAGATCTG
TTTAAAAGGAAAGCGCCTTGGGAATAA

Structures

Toxin

• AlphaFold DB: A0A2K9A201

Antitoxin

• AlphaFold DB: A0A2K9A963