Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /DUF1778(antitoxin) |
| Location | 1436875..1437671 | Replicon | chromosome |
| Accession | NZ_CP015194 | ||
| Organism | Shewanella sp. Pdp11 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | AYJ58_RS06355 | Protein ID | WP_106649443.1 |
| Coordinates | 1437141..1437671 (+) | Length | 177 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | B8ECY1 |
| Locus tag | AYJ58_RS06350 | Protein ID | WP_012586779.1 |
| Coordinates | 1436875..1437144 (+) | Length | 90 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AYJ58_RS06330 | 1433377..1434051 | + | 675 | WP_106649439.1 | Fe2+-dependent dioxygenase | - |
| AYJ58_RS06335 | 1434489..1434974 | + | 486 | WP_106649440.1 | hypothetical protein | - |
| AYJ58_RS06340 | 1435083..1435778 | + | 696 | WP_198555612.1 | hypothetical protein | - |
| AYJ58_RS06345 | 1436351..1436707 | + | 357 | WP_106649442.1 | hypothetical protein | - |
| AYJ58_RS06350 | 1436875..1437144 | + | 270 | WP_012586779.1 | DUF1778 domain-containing protein | Antitoxin |
| AYJ58_RS06355 | 1437141..1437671 | + | 531 | WP_106649443.1 | GNAT family N-acetyltransferase | Toxin |
| AYJ58_RS06360 | 1438057..1438428 | + | 372 | WP_106649444.1 | DUF2750 domain-containing protein | - |
| AYJ58_RS06365 | 1438509..1438820 | - | 312 | WP_106649445.1 | hypothetical protein | - |
| AYJ58_RS06370 | 1438817..1439047 | - | 231 | WP_106649446.1 | hypothetical protein | - |
| AYJ58_RS06375 | 1439044..1439322 | - | 279 | WP_106649447.1 | hypothetical protein | - |
| AYJ58_RS06380 | 1439323..1439631 | - | 309 | WP_106649448.1 | hypothetical protein | - |
| AYJ58_RS06385 | 1439628..1440278 | - | 651 | WP_106649449.1 | hypothetical protein | - |
| AYJ58_RS06390 | 1440275..1440664 | - | 390 | WP_106649450.1 | hypothetical protein | - |
| AYJ58_RS06395 | 1440661..1441290 | - | 630 | WP_106649451.1 | hypothetical protein | - |
| AYJ58_RS06400 | 1441321..1441668 | - | 348 | WP_025007746.1 | hypothetical protein | - |
| AYJ58_RS06405 | 1441694..1441954 | - | 261 | WP_106649452.1 | pyocin activator PrtN family protein | - |
| AYJ58_RS06410 | 1441951..1442304 | - | 354 | WP_012196661.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1426915..1491924 | 65009 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 177 a.a. Molecular weight: 19747.97 Da Isoelectric Point: 8.6014
>T62603 WP_106649443.1 NZ_CP015194:1437141-1437671 [Shewanella sp. Pdp11]
VSYSKTFKELDKSQHDRASFDCGEAELNDFIQTQAAKHMQAGISRTMFLPAATPLPNQKYPICSFYTIAPSSICRDTLPQ
AMGKKLPRYPIPVFLLAQLAVHKEFHGSGLGKASLIKALEYLWEINAHMRAYAIVVDCLTGQAESFYAKYGFEVLCEING
RVRMFIPMKTVGQLFT
VSYSKTFKELDKSQHDRASFDCGEAELNDFIQTQAAKHMQAGISRTMFLPAATPLPNQKYPICSFYTIAPSSICRDTLPQ
AMGKKLPRYPIPVFLLAQLAVHKEFHGSGLGKASLIKALEYLWEINAHMRAYAIVVDCLTGQAESFYAKYGFEVLCEING
RVRMFIPMKTVGQLFT
Download Length: 531 bp
>T62603 NZ_CP015194:1437141-1437671 [Shewanella sp. Pdp11]
GTGAGTTATTCCAAGACTTTTAAAGAATTGGATAAATCACAACACGATAGAGCATCATTTGACTGTGGCGAAGCAGAGTT
AAACGATTTTATCCAAACTCAAGCAGCGAAACACATGCAAGCAGGTATTAGCCGTACAATGTTTTTACCTGCTGCTACGC
CATTACCCAATCAAAAATACCCAATTTGCTCGTTTTATACTATCGCACCAAGTTCAATTTGCCGTGATACCTTGCCGCAA
GCCATGGGTAAAAAGTTACCACGCTATCCCATTCCGGTCTTTCTGCTTGCTCAACTTGCCGTCCATAAAGAGTTTCATGG
CAGTGGGTTAGGTAAAGCTAGTTTAATCAAAGCGCTAGAATACCTTTGGGAGATTAACGCTCACATGCGAGCTTATGCCA
TTGTTGTCGATTGTTTAACTGGCCAAGCTGAGTCATTTTACGCTAAGTATGGTTTCGAGGTGCTTTGTGAAATCAACGGT
CGTGTAAGAATGTTTATTCCAATGAAAACAGTCGGTCAGTTATTCACTTAG
GTGAGTTATTCCAAGACTTTTAAAGAATTGGATAAATCACAACACGATAGAGCATCATTTGACTGTGGCGAAGCAGAGTT
AAACGATTTTATCCAAACTCAAGCAGCGAAACACATGCAAGCAGGTATTAGCCGTACAATGTTTTTACCTGCTGCTACGC
CATTACCCAATCAAAAATACCCAATTTGCTCGTTTTATACTATCGCACCAAGTTCAATTTGCCGTGATACCTTGCCGCAA
GCCATGGGTAAAAAGTTACCACGCTATCCCATTCCGGTCTTTCTGCTTGCTCAACTTGCCGTCCATAAAGAGTTTCATGG
CAGTGGGTTAGGTAAAGCTAGTTTAATCAAAGCGCTAGAATACCTTTGGGAGATTAACGCTCACATGCGAGCTTATGCCA
TTGTTGTCGATTGTTTAACTGGCCAAGCTGAGTCATTTTACGCTAAGTATGGTTTCGAGGTGCTTTGTGAAATCAACGGT
CGTGTAAGAATGTTTATTCCAATGAAAACAGTCGGTCAGTTATTCACTTAG
Antitoxin
Download Length: 90 a.a. Molecular weight: 9903.38 Da Isoelectric Point: 4.9059
>AT62603 WP_012586779.1 NZ_CP015194:1436875-1437144 [Shewanella sp. Pdp11]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVIAEHESITVKADVFDQFIMACDEAKAPNKALREAA
AFTKRGEFK
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVIAEHESITVKADVFDQFIMACDEAKAPNKALREAA
AFTKRGEFK
Download Length: 270 bp
>AT62603 NZ_CP015194:1436875-1437144 [Shewanella sp. Pdp11]
ATGGCTACTGCAAGACTTGATATCCGTTTGGATGAAGAGATCAAAGCTAAGGCTGAGAAAGCATCGGCTTTGCTTGGGTT
AAAAAGCTTAACTGAATACGTTGTTCGCTTAATGGACGAAGATTCAACTCAGGTGATTGCTGAGCATGAAAGCATTACTG
TTAAAGCTGATGTGTTCGACCAATTCATAATGGCTTGTGATGAGGCTAAGGCCCCGAACAAGGCATTGCGTGAAGCGGCA
GCATTTACTAAACGTGGTGAGTTTAAGTGA
ATGGCTACTGCAAGACTTGATATCCGTTTGGATGAAGAGATCAAAGCTAAGGCTGAGAAAGCATCGGCTTTGCTTGGGTT
AAAAAGCTTAACTGAATACGTTGTTCGCTTAATGGACGAAGATTCAACTCAGGTGATTGCTGAGCATGAAAGCATTACTG
TTAAAGCTGATGTGTTCGACCAATTCATAATGGCTTGTGATGAGGCTAAGGCCCCGAACAAGGCATTGCGTGAAGCGGCA
GCATTTACTAAACGTGGTGAGTTTAAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|