Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 232798..233348 Replicon chromosome
Accession NZ_CP015194
Organism Shewanella sp. Pdp11

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AYJ58_RS01090 Protein ID WP_106648378.1
Coordinates 233049..233348 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag AYJ58_RS01085 Protein ID WP_106648377.1
Coordinates 232798..233040 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYJ58_RS01060 227879..229099 + 1221 WP_198555565.1 beta-ketoacyl-[acyl-carrier-protein] synthase family protein -
AYJ58_RS01065 229104..229637 + 534 WP_106648373.1 hotdog family protein -
AYJ58_RS01070 229750..230475 + 726 WP_106648374.1 3-ketoacyl-ACP reductase FabG2 -
AYJ58_RS01075 230476..231735 + 1260 WP_106648375.1 beta-ketoacyl-ACP synthase -
AYJ58_RS01080 231764..232507 + 744 WP_106648376.1 hypothetical protein -
AYJ58_RS01085 232798..233040 + 243 WP_106648377.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
AYJ58_RS01090 233049..233348 + 300 WP_106648378.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AYJ58_RS01095 233954..234892 + 939 WP_106648379.1 hypothetical protein -
AYJ58_RS01100 234949..235440 + 492 WP_106648380.1 hypothetical protein -
AYJ58_RS01105 236122..236577 + 456 WP_106648381.1 GNAT family N-acetyltransferase -
AYJ58_RS01110 236630..237817 - 1188 WP_106648382.1 benzoate/H(+) symporter BenE family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-64)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11641.31 Da        Isoelectric Point: 9.3236

>T62602 WP_106648378.1 NZ_CP015194:233049-233348 [Shewanella sp. Pdp11]
MKNKRYKLSRLSQTHLQQIKDYTIQHFSESQWHKYKQSLISDLQMLADNPGLGRSCDDIYPNGFYFPIGKHTAYFTKEDD
FILIVALLGQPQLPQNHLK

Download         Length: 300 bp

>T62602 NZ_CP015194:233049-233348 [Shewanella sp. Pdp11]
ATGAAAAATAAACGCTATAAACTAAGTAGGTTATCTCAGACTCACCTACAACAGATTAAAGACTACACCATTCAACACTT
TTCTGAGTCGCAGTGGCACAAATACAAACAAAGCCTAATATCCGACTTGCAAATGTTAGCCGATAACCCCGGATTAGGCA
GAAGCTGCGACGATATTTACCCCAACGGATTCTACTTTCCTATTGGTAAACACACCGCCTACTTCACAAAAGAAGACGAC
TTCATCCTTATCGTTGCCCTGTTAGGTCAACCACAGCTACCGCAAAATCATCTGAAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8906.12 Da        Isoelectric Point: 5.0621

>AT62602 WP_106648377.1 NZ_CP015194:232798-233040 [Shewanella sp. Pdp11]
VQTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDFEQLEAMKADYLKHCFNAAKEDLAKGNVVDGEDFLNAL

Download         Length: 243 bp

>AT62602 NZ_CP015194:232798-233040 [Shewanella sp. Pdp11]
GTGCAAACATTAACAGCCAATGACGCCAAACGAAATTTCGGTGAGTTACTGCTAAATGCTCAACGCGAACCCATCAAGAT
CAGCAAAAACAGTAAAGATGCGGTTGTCGTGATGTCTATCCACGACTTCGAACAGCTTGAGGCGATGAAAGCCGACTATT
TGAAGCACTGTTTCAACGCAGCCAAAGAAGATTTAGCGAAGGGCAATGTGGTTGATGGTGAAGATTTTCTTAACGCCCTG
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References