Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4454551..4454819 Replicon chromosome
Accession NZ_CP015138
Organism Escherichia coli strain Ecol_732

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4454589..4454691 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4454551..4454819 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A4X18_RS21925 4451709..4453148 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
A4X18_RS21930 4453265..4453501 + 237 WP_001295499.1 DUF1480 family protein -
A4X18_RS21935 4453606..4453797 + 192 WP_001296140.1 YebW family protein -
A4X18_RS21940 4453798..4454454 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 4454551..4454819 + 269 - - Antitoxin
- 4454589..4454691 - 103 - - Toxin
A4X18_RS21950 4454849..4455190 - 342 WP_000976472.1 YebY family protein -
A4X18_RS21955 4455203..4456075 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
A4X18_RS21960 4456079..4456453 - 375 WP_000168747.1 CopC domain-containing protein YobA -
A4X18_RS21965 4456592..4456822 + 231 WP_000916763.1 DNA polymerase III subunit theta -
A4X18_RS21970 4456924..4457580 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
A4X18_RS21975 4457604..4458266 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T62491 NZ_CP015138:c4454691-4454589 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT62491 NZ_CP015138:4454551-4454819 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References