Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 7296752..7297299 Replicon chromosome
Accession NZ_CP015136
Organism Luteitalea pratensis strain DSM 100886 isolate HEG_-6_39

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LuPra_RS30665 Protein ID WP_110174301.1
Coordinates 7296752..7297102 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LuPra_RS30670 Protein ID WP_110174302.1
Coordinates 7297099..7297299 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LuPra_RS30625 7293300..7293728 - 429 WP_110174295.1 type II toxin-antitoxin system VapC family toxin -
LuPra_RS30630 7293725..7293997 - 273 WP_110174296.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
LuPra_RS30635 7294261..7294623 - 363 WP_110174297.1 hypothetical protein -
LuPra_RS30640 7294805..7295008 + 204 WP_110174298.1 hypothetical protein -
LuPra_RS30645 7295072..7295320 - 249 WP_110174299.1 type II toxin-antitoxin system HicB family antitoxin -
LuPra_RS30650 7295322..7295576 - 255 WP_110174943.1 type II toxin-antitoxin system HicA family toxin -
LuPra_RS30655 7295753..7296148 - 396 WP_110174300.1 PIN domain-containing protein -
LuPra_RS30660 7296145..7296435 - 291 WP_110174944.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
LuPra_RS30665 7296752..7297102 - 351 WP_110174301.1 PIN domain-containing protein Toxin
LuPra_RS30670 7297099..7297299 - 201 WP_110174302.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LuPra_RS30675 7297826..7299631 - 1806 WP_110174303.1 DEAD/DEAH box helicase -
LuPra_RS30680 7299715..7300233 + 519 WP_110174304.1 hypothetical protein -
LuPra_RS30685 7300220..7301719 - 1500 WP_110174305.1 hypothetical protein -
LuPra_RS30690 7301770..7301994 - 225 WP_110174306.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-111)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-47)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12693.78 Da        Isoelectric Point: 6.4900

>T62449 WP_110174301.1 NZ_CP015136:c7297102-7296752 [Luteitalea pratensis]
MTLVDTSVWIDHLRRGDAELAALLEEGMVLVHPFVIGEIACGTLRQREVVLGHLRHLPEAPLATETEVHHLLEGHRLGGR
GLGWVDLHLLASARLAAVPLITRDRALRDVAQAVLA

Download         Length: 351 bp

>T62449 NZ_CP015136:c7297102-7296752 [Luteitalea pratensis]
ATGACGCTCGTCGACACGTCGGTGTGGATCGACCACTTGCGCCGCGGCGACGCCGAACTCGCGGCGCTGCTCGAGGAAGG
CATGGTGCTCGTCCACCCGTTCGTGATCGGCGAGATCGCGTGCGGCACCCTGCGCCAGCGCGAGGTAGTGCTGGGGCATC
TGCGGCACCTGCCGGAGGCGCCCCTCGCCACCGAGACTGAGGTCCACCACCTTCTCGAGGGCCATCGTCTCGGCGGCCGG
GGGCTGGGGTGGGTCGACCTGCATCTGCTCGCGTCGGCGCGGCTCGCGGCGGTCCCGTTGATCACGCGGGACCGCGCGCT
GCGCGACGTCGCCCAGGCCGTGCTCGCCTGA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7464.56 Da        Isoelectric Point: 11.5790

>AT62449 WP_110174302.1 NZ_CP015136:c7297299-7297099 [Luteitalea pratensis]
MRTTMILDDTLLEEARRLTGVTEKTALVHEGLRALIAREHSSRLRRLAGSDPEASVADRSRRRPKP

Download         Length: 201 bp

>AT62449 NZ_CP015136:c7297299-7297099 [Luteitalea pratensis]
ATGAGGACGACCATGATCCTGGACGACACGTTGCTGGAGGAGGCCCGCCGGCTCACGGGGGTCACGGAGAAGACGGCGCT
GGTGCACGAGGGCTTGCGGGCCCTCATCGCCCGCGAGCATTCATCGCGGTTACGTCGCCTCGCGGGGTCGGACCCGGAGG
CCTCGGTGGCCGATCGGTCGCGACGCCGTCCGAAGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References