Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapB(antitoxin)
Location 6733994..6734580 Replicon chromosome
Accession NZ_CP015136
Organism Luteitalea pratensis strain DSM 100886 isolate HEG_-6_39

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LuPra_RS28240 Protein ID WP_110173867.1
Coordinates 6734212..6734580 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LuPra_RS28235 Protein ID WP_110173866.1
Coordinates 6733994..6734212 (+) Length 73 a.a.

Genomic Context

LuPra_RS28210LuPra_RS28215LuPra_RS28220LuPra_RS28235LuPra_RS28240LuPra_RS28245LuPra_RS28250LuPra_RS28225LuPra_RS28230LuPra_RS28255LuPra_RS28260LuPra_RS28265
Location: 6729240..6730148 (909 bp)
Type: Others
Protein ID: WP_110173861.1
Location: 6730353..6731456 (1104 bp)
Type: Others
Protein ID: WP_110173862.1
Location: 6731453..6732967 (1515 bp)
Type: Others
Protein ID: WP_110173863.1
Location: 6733994..6734212 (219 bp)
Type: Antitoxin
Protein ID: WP_110173866.1
Location: 6734212..6734580 (369 bp)
Type: Toxin
Protein ID: WP_110173867.1
Location: 6734806..6735672 (867 bp)
Type: Others
Protein ID: WP_110173868.1
Location: 6735822..6736952 (1131 bp)
Type: Others
Protein ID: WP_110173869.1
Location: 6732969..6733277 (309 bp)
Type: Others
Protein ID: WP_157899791.1
Location: 6733274..6733969 (696 bp)
Type: Others
Protein ID: WP_110173865.1
Location: 6737011..6737502 (492 bp)
Type: Others
Protein ID: WP_110173870.1
Location: 6737687..6738631 (945 bp)
Type: Others
Protein ID: WP_110174906.1
Location: 6738805..6739422 (618 bp)
Type: Others
Protein ID: WP_110173871.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LuPra_RS282106729240..6730148+909WP_110173861.1VWA domain-containing protein-
LuPra_RS282156730353..6731456+1104WP_110173862.1TIM barrel protein-
LuPra_RS282206731453..6732967+1515WP_110173863.1sulfatase-
LuPra_RS282256732969..6733277-309WP_157899791.1hypothetical protein-
LuPra_RS282306733274..6733969-696WP_110173865.1hypothetical protein-
LuPra_RS282356733994..6734212+219WP_110173866.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
LuPra_RS282406734212..6734580+369WP_110173867.1PIN domain-containing proteinToxin
LuPra_RS282456734806..6735672+867WP_110173868.1NAD(P)-dependent oxidoreductase-
LuPra_RS282506735822..6736952+1131WP_110173869.1lytic murein transglycosylase-
LuPra_RS282556737011..6737502-492WP_110173870.1peroxiredoxin-
LuPra_RS282606737687..6738631-945WP_110174906.1homocysteine S-methyltransferase family protein-
LuPra_RS282656738805..6739422-618WP_110173871.1GNAT family N-acetyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-115)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13757.92 Da        Isoelectric Point: 6.9791

>T62448 WP_110173867.1 NZ_CP015136:6734212-6734580 [Luteitalea pratensis]
MVLVDTSVWIRFLANRAPFARQLDELLGQGEVCGHDFVMGELLIGDKGGRKQLLADYALMRQAPVVSHREVVEFVRQRRL
HGRGIGWIDTHLLASALVSHIKLWTADPRLGEVARDLGIDYE

Download         Length: 369 bp

>T62448 NZ_CP015136:6734212-6734580 [Luteitalea pratensis]
ATGGTTCTTGTCGATACGTCGGTCTGGATACGCTTTCTTGCCAACCGGGCACCGTTTGCCCGGCAGCTCGATGAGCTGCT
CGGTCAGGGCGAGGTCTGCGGCCATGACTTCGTGATGGGTGAACTCCTGATTGGCGACAAGGGCGGCCGTAAGCAGCTCC
TGGCCGACTACGCGCTCATGCGCCAGGCGCCTGTCGTGTCGCACCGCGAGGTGGTCGAGTTCGTTCGCCAGCGCAGACTT
CACGGCCGTGGCATCGGATGGATCGACACGCACCTCCTCGCGTCGGCACTCGTGTCGCACATCAAGTTGTGGACCGCCGA
CCCTCGGCTCGGAGAGGTCGCGCGCGACCTGGGGATCGATTACGAATGA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8078.13 Da        Isoelectric Point: 11.6228

>AT62448 WP_110173866.1 NZ_CP015136:6733994-6734212 [Luteitalea pratensis]
MKKTLHIDDDLLREARSVSGARSDTDTVRLGLEALVRQGANERLRALRGKEPRATDVRRRREVSSPTKHSAA

Download         Length: 219 bp

>AT62448 NZ_CP015136:6733994-6734212 [Luteitalea pratensis]
ATGAAGAAGACACTTCACATCGACGACGACCTCTTGCGAGAGGCGCGATCGGTCAGTGGCGCCCGGAGTGACACGGATAC
GGTCCGCCTCGGGCTCGAGGCGCTGGTGCGGCAAGGCGCGAATGAGCGACTGCGGGCACTTCGGGGGAAGGAGCCGCGGG
CTACTGATGTTCGGCGTCGACGTGAAGTCTCCTCGCCAACGAAACACTCTGCAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References