Detailed information of TA system TA062445

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacT-ataR/DUF1778(antitoxin)
• Location: 1363205..1364040
• Replicon: chromosome
• Accession: NZ_CP015136
• Organism: Luteitalea pratensis strain DSM 100886 isolate HEG_-6_39

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: LuPra_RS05695
• Protein ID: WP_110169850.1
• Coordinates: 1363522..1364040 (+)
• Length: 173 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: LuPra_RS05690
• Protein ID: WP_110169849.1
• Coordinates: 1363205..1363525 (+)
• Length: 107 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LuPra_RS05660	1358231..1359256	-	1026	WP_110169845.1	hypothetical protein	-
LuPra_RS05665	1359306..1359917	+	612	WP_110169846.1	DUF4203 domain-containing protein	-
LuPra_RS05670	1359986..1360957	+	972	WP_110169847.1	sugar phosphate isomerase/epimerase	-
LuPra_RS05675	1360965..1361261	-	297	WP_110174544.1	metalloregulator ArsR/SmtB family transcription factor	-
LuPra_RS05680	1361611..1362429	+	819	WP_157898783.1	transporter	-
LuPra_RS05690	1363205..1363525	+	321	WP_110169849.1	DUF1778 domain-containing protein	Antitoxin
LuPra_RS05695	1363522..1364040	+	519	WP_110169850.1	GNAT family N-acetyltransferase	Toxin
LuPra_RS05700	1364195..1364674	-	480	WP_110169851.1	SRPBCC domain-containing protein	-
LuPra_RS05705	1364685..1365050	-	366	WP_110169852.1	helix-turn-helix domain-containing protein	-
LuPra_RS05710	1365350..1365625	-	276	WP_110169853.1	hypothetical protein	-
LuPra_RS05715	1365640..1365990	-	351	WP_110169854.1	hypothetical protein	-
LuPra_RS05720	1366406..1367416	-	1011	WP_110169855.1	serine hydrolase	-
LuPra_RS05725	1367682..1368212	-	531	WP_110169856.1	dihydrofolate reductase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (46-147)

Antitoxin

• Vibrio phage ICP1, Orf50 (25-100)

Sequences

Toxin

Protein

• Length: 173 a.a.
• Molecular weight: 18352.00 Da
• Isoelectric Point: 7.4667

>T62445 WP_110169850.1 NZ_CP015136:1363522-1364040 [Luteitalea pratensis]
MSAAGISAPEHLTAEHDVSSFDSGTPELDNWLKRRALANEALGTSRTYVVTEGGRVVAFYALANGAVAHKDVFAKTKRNM
PDPIPVMVLARSAVDSAYQKQGLGSALLRDALFRTIAAAQIAGIRAVLLHAMSDDAKRTYARAGFHEGPVDPMMMMITLA
EVEKNLSPPSAS

Nucleotide

• Length: 519 bp

>T62445 NZ_CP015136:1363522-1364040 [Luteitalea pratensis]
ATGAGTGCGGCAGGAATTAGCGCTCCAGAGCACCTGACAGCCGAGCACGACGTCAGCTCTTTCGACTCCGGTACGCCTGA
ACTCGACAATTGGCTGAAACGCCGAGCGCTTGCGAATGAGGCGCTGGGCACTTCACGGACCTACGTCGTGACAGAAGGCG
GACGTGTGGTCGCCTTCTATGCGCTTGCAAACGGCGCCGTTGCTCACAAGGACGTGTTCGCCAAAACGAAGCGCAACATG
CCGGATCCAATTCCGGTGATGGTGCTTGCGCGTTCGGCCGTCGATTCCGCCTACCAGAAACAAGGTCTTGGTTCCGCGCT
TCTAAGGGACGCCCTATTCCGCACCATCGCGGCCGCTCAAATCGCTGGCATTCGCGCGGTGCTGCTTCACGCGATGTCAG
ATGACGCGAAGCGCACCTATGCACGTGCCGGATTTCACGAGGGTCCGGTCGATCCAATGATGATGATGATTACGCTCGCA
GAGGTTGAGAAGAACCTCAGCCCGCCCAGCGCGAGCTGA

Antitoxin

Protein

• Length: 107 a.a.
• Molecular weight: 12032.61 Da
• Isoelectric Point: 11.5201

>AT62445 WP_110169849.1 NZ_CP015136:1363205-1363525 [Luteitalea pratensis]
MSRHGRHNREQTMAAPATAARTRTINIRIEEERRTLIDRAAAVAGKDRTQFVLNAATREATTVLLDQRYFQLDTAAFAKF
NAALDASPAENPRLRELLSRKAPWER

Nucleotide

• Length: 321 bp

>AT62445 NZ_CP015136:1363205-1363525 [Luteitalea pratensis]
ATGTCTCGACATGGGCGTCACAATAGAGAGCAAACCATGGCAGCCCCTGCAACCGCCGCGCGGACACGAACCATCAATAT
CCGCATCGAGGAAGAGCGACGCACGCTCATCGATCGAGCCGCTGCAGTTGCCGGGAAGGACCGTACTCAGTTCGTTCTGA
ACGCAGCAACCCGTGAAGCGACAACTGTACTTCTCGACCAGCGGTATTTTCAGCTGGACACAGCTGCGTTCGCGAAGTTC
AACGCTGCCCTGGATGCGTCTCCCGCCGAGAACCCGCGGCTGCGCGAGCTTCTCTCTAGAAAAGCTCCCTGGGAACGATG
A