Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 929772..930469 Replicon chromosome
Accession NZ_CP015136
Organism Luteitalea pratensis strain DSM 100886 isolate HEG_-6_39

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LuPra_RS04040 Protein ID WP_110169564.1
Coordinates 930035..930469 (+) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LuPra_RS04035 Protein ID WP_110169563.1
Coordinates 929772..930038 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LuPra_RS04010 925482..925901 - 420 WP_110169558.1 hypothetical protein -
LuPra_RS04015 926211..927674 + 1464 WP_110169559.1 winged helix-turn-helix domain-containing protein -
LuPra_RS04020 927950..928153 + 204 WP_110169560.1 hypothetical protein -
LuPra_RS04025 928299..928526 - 228 WP_110169561.1 MarR family transcriptional regulator -
LuPra_RS04030 928615..929634 + 1020 WP_157898711.1 PD40 domain-containing protein -
LuPra_RS04035 929772..930038 + 267 WP_110169563.1 antitoxin Antitoxin
LuPra_RS04040 930035..930469 + 435 WP_110169564.1 type II toxin-antitoxin system VapC family toxin Toxin
LuPra_RS04045 930519..931790 - 1272 WP_110169565.1 DUF418 domain-containing protein -
LuPra_RS04050 932146..932745 - 600 WP_157898713.1 hypothetical protein -
LuPra_RS04060 933133..933573 + 441 Protein_790 PD40 domain-containing protein -
LuPra_RS31565 933640..934017 + 378 Protein_791 PD40 domain-containing protein -
LuPra_RS04070 934072..934548 + 477 Protein_792 PD40 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-134)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15916.15 Da        Isoelectric Point: 6.0858

>T62444 WP_110169564.1 NZ_CP015136:930035-930469 [Luteitalea pratensis]
VKIVDLNILLYAINAEAAQHQSARQWWERTVNDGEEVIGLPWVVLLGFLRLSTNPRVFPRPLTPDAAAAKVDTWLALDNV
RVVREKDEHWEVLKSLLATSGAAGNLTTDAHLAALALTHDAVLVSSDTDFARFRGLRLENALRG

Download         Length: 435 bp

>T62444 NZ_CP015136:930035-930469 [Luteitalea pratensis]
GTGAAGATCGTCGACCTGAACATCCTGCTCTACGCCATCAACGCCGAGGCGGCCCAGCACCAGAGCGCGCGTCAGTGGTG
GGAGCGCACCGTCAACGACGGCGAGGAGGTGATCGGGCTGCCATGGGTGGTCCTGCTCGGCTTCCTGCGACTGTCCACCA
ATCCCCGCGTGTTCCCGCGCCCGCTCACGCCCGATGCCGCGGCAGCGAAAGTGGACACATGGCTCGCCCTCGACAACGTC
CGTGTCGTGCGGGAGAAGGACGAGCACTGGGAAGTCCTGAAATCGCTGCTGGCCACCAGCGGCGCCGCGGGGAATCTCAC
CACCGATGCGCACCTCGCGGCCCTCGCGCTCACCCATGACGCCGTGCTGGTGTCGAGTGATACGGACTTCGCGCGCTTCA
GGGGCCTGAGGCTGGAGAACGCCTTGCGGGGCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9878.62 Da        Isoelectric Point: 11.6335

>AT62444 WP_110169563.1 NZ_CP015136:929772-930038 [Luteitalea pratensis]
MRTTVRLDDVLLERLKAQARAEKVSLTRMLNRALKAGLDAGGARKRPRRAYRERVHAMGVPRVALDKALAMAAALEDEEV
VRELATRK

Download         Length: 267 bp

>AT62444 NZ_CP015136:929772-930038 [Luteitalea pratensis]
ATGCGGACCACGGTACGCCTCGATGATGTGCTGCTCGAGCGCCTGAAGGCCCAGGCGCGGGCCGAGAAAGTGAGCCTCAC
GCGCATGCTCAACCGCGCCCTGAAGGCGGGGCTCGATGCAGGAGGCGCGCGCAAGCGACCGCGACGGGCCTATCGGGAGC
GGGTGCACGCGATGGGCGTTCCTCGCGTCGCCCTCGACAAGGCGCTGGCGATGGCCGCCGCGCTCGAAGACGAGGAAGTC
GTCCGCGAACTCGCGACTCGCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References