Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4609461..4609606 | Replicon | chromosome |
| Accession | NZ_CP015134 | ||
| Organism | Klebsiella pneumoniae strain ATCC 35657 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4609468..4609570 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4609461..4609606 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| WM93_RS23905 | 4604992..4606425 | + | 1434 | WP_064156927.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| WM93_RS23910 | 4606541..4606780 | + | 240 | WP_002911393.1 | YebV family protein | - |
| WM93_RS23915 | 4606878..4607069 | + | 192 | WP_002911395.1 | YebW family protein | - |
| WM93_RS23920 | 4607066..4607719 | - | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| WM93_RS23925 | 4607876..4608844 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| WM93_RS28630 | 4608949..4609092 | + | 144 | WP_038431282.1 | Ecr family regulatory small membrane protein | - |
| - | 4609461..4609606 | + | 146 | - | - | Antitoxin |
| - | 4609468..4609570 | - | 103 | - | - | Toxin |
| WM93_RS23940 | 4609729..4610067 | - | 339 | WP_002911404.1 | YebY family protein | - |
| WM93_RS23945 | 4610084..4610953 | - | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| WM93_RS23950 | 4610957..4611331 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| WM93_RS23955 | 4611444..4611674 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| WM93_RS23960 | 4611753..4612412 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| WM93_RS23970 | 4612416..4614476 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T62435 NZ_CP015134:c4609570-4609468 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT62435 NZ_CP015134:4609461-4609606 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
