Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1309454..1309599 Replicon chromosome
Accession NZ_CP015130
Organism Klebsiella pneumoniae strain Kpn555

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1309461..1309563 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1309454..1309599 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WM92_RS06690 1304986..1306419 + 1434 WP_064839198.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
WM92_RS06695 1306535..1306774 + 240 WP_002911393.1 YebV family protein -
WM92_RS06700 1306872..1307063 + 192 WP_002911395.1 YebW family protein -
WM92_RS06705 1307060..1307713 - 654 WP_032415192.1 protein-serine/threonine phosphatase -
WM92_RS06710 1307870..1308838 + 969 WP_014907334.1 VirK/YbjX family protein -
WM92_RS30775 1308943..1309086 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1309454..1309599 + 146 - - Antitoxin
- 1309461..1309563 - 103 - - Toxin
WM92_RS06720 1309722..1310060 - 339 WP_002911404.1 YebY family protein -
WM92_RS06725 1310077..1310946 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
WM92_RS06730 1310950..1311324 - 375 WP_064145947.1 CopC domain-containing protein YobA -
WM92_RS06735 1311437..1311667 + 231 WP_002911406.1 DNA polymerase III subunit theta -
WM92_RS06740 1311746..1312405 + 660 WP_002911407.1 exodeoxyribonuclease X -
WM92_RS06745 1312409..1314469 - 2061 WP_064839200.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T62407 NZ_CP015130:c1309563-1309461 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT62407 NZ_CP015130:1309454-1309599 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References