Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1912374..1912519 Replicon chromosome
Accession NZ_CP015120
Organism Klebsiella pneumoniae strain kp757

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1912410..1912512 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1912374..1912519 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A4U70_RS09465 1907504..1909564 + 2061 WP_004151449.1 oligopeptidase B -
A4U70_RS09470 1909568..1910227 - 660 WP_002911407.1 exodeoxyribonuclease X -
A4U70_RS09475 1910306..1910536 - 231 WP_002911406.1 DNA polymerase III subunit theta -
A4U70_RS09480 1910649..1911023 + 375 WP_004151448.1 CopC domain-containing protein YobA -
A4U70_RS09485 1911027..1911896 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
A4U70_RS09490 1911913..1912251 + 339 WP_002911404.1 YebY family protein -
- 1912374..1912519 - 146 - - Antitoxin
- 1912410..1912512 + 103 - - Toxin
A4U70_RS26830 1912886..1913029 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
A4U70_RS09500 1913134..1914102 - 969 WP_004151446.1 VirK/YbjX family protein -
A4U70_RS09505 1914259..1914912 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
A4U70_RS09510 1914909..1915100 - 192 WP_002911395.1 YebW family protein -
A4U70_RS09515 1915198..1915437 - 240 WP_002911393.1 YebV family protein -
A4U70_RS09520 1915553..1916986 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T62389 NZ_CP015120:1912410-1912512 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT62389 NZ_CP015120:c1912519-1912374 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References