Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4332390..4333053 Replicon chromosome
Accession NZ_CP015113
Organism Kosakonia radicincitans strain GXGL-4A

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag A3780_RS20365 Protein ID WP_007370254.1
Coordinates 4332390..4332806 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag A3780_RS20370 Protein ID WP_007370253.1
Coordinates 4332787..4333053 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A3780_RS20345 4328376..4330109 - 1734 WP_035889603.1 single-stranded-DNA-specific exonuclease RecJ -
A3780_RS20350 4330115..4330828 - 714 WP_007370257.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
A3780_RS20355 4330853..4331749 - 897 WP_035889602.1 site-specific tyrosine recombinase XerD -
A3780_RS20360 4331850..4332371 + 522 WP_007370255.1 flavodoxin FldB -
A3780_RS20365 4332390..4332806 - 417 WP_007370254.1 protein YgfX Toxin
A3780_RS20370 4332787..4333053 - 267 WP_007370253.1 FAD assembly factor SdhE Antitoxin
A3780_RS20375 4333301..4334281 + 981 WP_007370252.1 tRNA-modifying protein YgfZ -
A3780_RS20380 4334321..4334980 - 660 WP_007370251.1 hemolysin III family protein -
A3780_RS20385 4335332..4336060 + 729 WP_007370250.1 MurR/RpiR family transcriptional regulator -
A3780_RS20390 4336177..4337610 + 1434 WP_071921388.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16350.31 Da        Isoelectric Point: 10.7373

>T62370 WP_007370254.1 NZ_CP015113:c4332806-4332390 [Kosakonia radicincitans]
VVLWQSELRVSWRAQWISLLLHGLGAALILLMPWPLSYTPLWLLLLSLVVFDCVRSQRRINACHGELKLLMDSRLRWQGM
EWDIIGTPWMLRSGMMLRLRREEDGRRQHLWLAADSMDAQEWRDLRRVISQKPAQGLH

Download         Length: 417 bp

>T62370 NZ_CP015113:c4332806-4332390 [Kosakonia radicincitans]
GTGGTCCTGTGGCAATCTGAGTTACGCGTCTCCTGGCGCGCACAATGGATTTCGCTTTTGCTCCACGGTCTGGGCGCTGC
ACTCATTTTGCTGATGCCCTGGCCTTTGAGTTACACACCGCTGTGGCTGCTGTTGCTGTCGCTGGTGGTTTTTGATTGCG
TGCGCAGCCAGCGGCGGATCAATGCCTGTCATGGCGAACTCAAACTGCTGATGGATTCCCGCCTGCGCTGGCAGGGCATG
GAATGGGATATCATCGGAACGCCGTGGATGTTACGTAGTGGAATGATGCTGCGCTTGCGCCGTGAAGAGGATGGGCGCCG
TCAACATTTATGGCTGGCGGCAGACAGCATGGATGCGCAGGAGTGGCGCGATCTGCGCCGGGTGATATCACAGAAACCGG
CGCAGGGGCTGCATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10557.98 Da        Isoelectric Point: 5.1069

>AT62370 WP_007370253.1 NZ_CP015113:c4333053-4332787 [Kosakonia radicincitans]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQLFVRLLESDDPDLFNWLMNHGKPQDTELQRMVQLIQTRN
RDRGPVAI

Download         Length: 267 bp

>AT62370 NZ_CP015113:c4333053-4332787 [Kosakonia radicincitans]
ATGGATATTAACAACAAAGCCCGTATCCACTGGGCGTGCCGCCGTGGAATGCGTGAACTCGACATCTCAATAATGCCTTT
TTTCGAACATGAGTACGACACGCTGAGCGATGATGACAAACAGCTGTTTGTTCGTCTGCTGGAAAGTGACGATCCTGATT
TATTCAACTGGTTAATGAATCACGGTAAGCCTCAGGACACGGAGTTACAAAGAATGGTGCAGTTAATCCAGACACGGAAT
CGGGATCGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References