Detailed information of TA system TA062360

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1672001..1672905
• Replicon: chromosome
• Accession: NZ_CP015113
• Organism: Kosakonia radicincitans strain GXGL-4A

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: A3780_RS07845
• Protein ID: WP_007374122.1
• Coordinates: 1672001..1672465 (-)
• Length: 155 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: A3780_RS07850
• Protein ID: WP_007374123.1
• Coordinates: 1672462..1672905 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A3780_RS07830	1668689..1668910	-	222	WP_007374119.1	cold shock-like protein CspD	-
A3780_RS07835	1669239..1669559	+	321	WP_007374120.1	ATP-dependent Clp protease adapter ClpS	-
A3780_RS07840	1669591..1671879	+	2289	WP_035885867.1	ATP-dependent Clp protease ATP-binding subunit ClpA	-
A3780_RS07845	1672001..1672465	-	465	WP_007374122.1	RES domain-containing protein	Toxin
A3780_RS07850	1672462..1672905	-	444	WP_007374123.1	DUF2384 domain-containing protein	Antitoxin
A3780_RS07855	1673054..1673272	-	219	WP_001040187.1	translation initiation factor IF-1	-
A3780_RS07860	1673557..1674261	-	705	WP_007374124.1	leucyl/phenylalanyl-tRNA--protein transferase	-
A3780_RS07865	1674367..1676088	-	1722	WP_071920555.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-
A3780_RS07870	1676089..1677855	-	1767	WP_071920556.1	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-148)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (29-90)

Sequences

Toxin

Protein

• Length: 155 a.a.
• Molecular weight: 17044.40 Da
• Isoelectric Point: 6.0751

>T62360 WP_007374122.1 NZ_CP015113:c1672465-1672001 [Kosakonia radicincitans]
VIFYRLVSRRYASEAWTGSGANQYGGRWNHKGHPAVYIASSVSLAALEMLVHVRSDTILSQYGLFSIDIPDKEIEYLDKQ
WLPPDWQENPAPLSTMDLGTAWLEANSAVALVVPSCVIPLENNAILNPQHAGFSKLLKSVKELPFSFDARLASS

Nucleotide

• Length: 465 bp

>T62360 NZ_CP015113:c1672465-1672001 [Kosakonia radicincitans]
GTGATTTTTTATCGCCTTGTGTCGCGCCGCTACGCCAGCGAAGCCTGGACCGGCAGCGGTGCGAATCAATATGGCGGCAG
ATGGAATCACAAAGGTCACCCGGCGGTTTATATTGCCTCATCCGTTTCCCTCGCCGCGCTGGAAATGCTGGTGCATGTAC
GCAGCGACACGATCCTTAGCCAGTACGGCCTGTTCAGTATCGACATTCCCGATAAAGAGATTGAATATCTGGATAAACAG
TGGCTGCCGCCGGACTGGCAGGAAAACCCGGCTCCGCTTTCAACGATGGATCTGGGAACCGCCTGGCTGGAAGCCAACAG
CGCCGTCGCGCTGGTAGTTCCTTCCTGCGTCATTCCTCTGGAAAACAATGCCATCCTCAATCCACAGCACGCTGGATTCA
GCAAGTTACTCAAATCAGTAAAAGAGCTTCCTTTTTCGTTTGATGCGCGTCTGGCTTCATCCTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16407.90 Da
• Isoelectric Point: 9.9132

>AT62360 WP_007374123.1 NZ_CP015113:c1672905-1672462 [Kosakonia radicincitans]
MRTWSPEQKPVENALWRFAGFPANRGIKLVQMLNEGLPVSILDNIHEWTEMSRSDILRVTGINERNVARRKSAGRTLTPE
ESERIARLVRVIDAAVQFFGDKKMAYAWLQAPVRGLGNVAPISLIATESGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT62360 NZ_CP015113:c1672905-1672462 [Kosakonia radicincitans]
ATGAGAACCTGGAGCCCGGAACAAAAACCGGTTGAAAATGCACTCTGGCGTTTCGCCGGTTTCCCCGCTAACCGCGGTAT
AAAACTTGTTCAGATGTTGAATGAGGGTTTGCCTGTCAGCATTCTGGATAATATCCATGAGTGGACGGAGATGTCTCGCT
CCGACATCCTGCGTGTCACCGGTATTAACGAGCGCAATGTCGCCCGCCGTAAGAGCGCGGGACGCACCTTAACGCCGGAA
GAGAGCGAGCGGATCGCCCGCTTGGTTCGCGTGATCGACGCCGCCGTTCAGTTTTTTGGTGATAAAAAAATGGCGTACGC
CTGGCTGCAAGCGCCGGTACGCGGCCTCGGTAACGTTGCTCCTATCTCCCTGATTGCGACTGAAAGTGGCGCACTGGAAG
TCACCGATCTGATTGGCCGCCTGGAGCACGGAGTATTTGCGTGA