Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 711720..712359 Replicon chromosome
Accession NZ_CP015099
Organism Glaesserella parasuis strain SC1401

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A4U84_RS03275 Protein ID WP_062923995.1
Coordinates 711720..712055 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A4U84_RS03280 Protein ID WP_173668573.1
Coordinates 712063..712359 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A4U84_RS03235 707416..707778 - 363 WP_062923991.1 hypothetical protein -
A4U84_RS03240 707919..708491 + 573 WP_021116087.1 sigma-70 family RNA polymerase sigma factor -
A4U84_RS03245 708488..708673 + 186 WP_005713975.1 zf-HC2 domain-containing protein -
A4U84_RS11010 708862..709605 - 744 Protein_646 transposase -
A4U84_RS03260 709697..710635 - 939 WP_062923993.1 hypothetical protein -
A4U84_RS03265 710698..711042 - 345 WP_062923994.1 hypothetical protein -
A4U84_RS03270 711157..711561 - 405 WP_021110905.1 DNA polymerase III subunit psi -
A4U84_RS03275 711720..712055 + 336 WP_062923995.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A4U84_RS03280 712063..712359 + 297 WP_173668573.1 putative addiction module antidote protein Antitoxin
A4U84_RS03285 712432..713421 + 990 WP_035524355.1 16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC -
A4U84_RS03290 713522..714647 + 1126 Protein_653 IS3 family transposase -
A4U84_RS11015 714675..715004 - 330 Protein_654 transposase -
A4U84_RS03300 715393..715996 + 604 Protein_655 transposase -
A4U84_RS03305 716120..717307 - 1188 WP_062923998.1 elongation factor Tu -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 701765..715004 13239


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-96)

Antitoxin

Uncharacterized protein HI1420

(7-91)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12064.80 Da        Isoelectric Point: 9.8168

>T62338 WP_062923995.1 NZ_CP015099:711720-712055 [Glaesserella parasuis]
MSGIINQIVITDNFSKWLDGLKNPIAKATVARRIKNAVKGNFGDHKALAGTGGLYEMRIATGAGYRIYYAQQGDVIYILL
QGGDKSTLQADIEKAKALWAELKQTGGSNEY

Download         Length: 336 bp

>T62338 NZ_CP015099:711720-712055 [Glaesserella parasuis]
ATGTCAGGAATTATCAACCAAATCGTCATTACAGATAATTTTTCAAAGTGGCTAGATGGTTTAAAAAATCCTATTGCTAA
AGCAACAGTGGCAAGAAGAATTAAGAATGCAGTAAAAGGTAATTTTGGTGATCATAAAGCGCTTGCAGGTACTGGTGGAC
TTTATGAAATGCGAATAGCGACAGGCGCTGGTTATCGAATTTACTATGCACAGCAGGGCGATGTTATTTATATTCTGTTA
CAAGGTGGTGATAAATCAACACTGCAAGCCGATATTGAGAAAGCGAAAGCATTGTGGGCAGAATTAAAACAGACAGGAGG
AAGTAATGAATATTAA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10948.49 Da        Isoelectric Point: 4.8951

>AT62338 WP_173668573.1 NZ_CP015099:712063-712359 [Glaesserella parasuis]
MAEKHGLRPFDVAEFLDNEETIQAYLAEVLKEGDQDEFLEALNDVARARGIAELAKQTGLGRESLYKTLSKGSKPRFETI
QKILGAFNLVLLPQIKNS

Download         Length: 297 bp

>AT62338 NZ_CP015099:712063-712359 [Glaesserella parasuis]
ATGGCAGAAAAACACGGTTTACGTCCTTTTGATGTCGCTGAATTTTTGGATAACGAAGAAACAATACAAGCCTATTTAGC
AGAAGTATTAAAAGAGGGCGATCAAGATGAGTTTTTGGAAGCCCTTAATGATGTAGCAAGAGCAAGGGGGATCGCAGAAC
TTGCGAAGCAAACGGGGTTAGGTAGAGAAAGTTTATATAAAACCCTATCTAAAGGAAGTAAACCTCGTTTTGAAACTATT
CAAAAAATTTTAGGAGCATTTAATCTTGTGCTTCTCCCACAAATAAAAAATAGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References