Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/PRK09907(toxin) |
Location | 2307020..2307650 | Replicon | chromosome |
Accession | NZ_CP015081 | ||
Organism | Deinococcus radiodurans R1 |
Toxin (Protein)
Gene name | mazF | Uniprot ID | Q9RX98 |
Locus tag | A2G07_RS11445 | Protein ID | WP_010887062.1 |
Coordinates | 2307297..2307650 (-) | Length | 118 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | - |
Locus tag | A2G07_RS11440 | Protein ID | WP_162177573.1 |
Coordinates | 2307020..2307244 (-) | Length | 75 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
A2G07_RS11415 | 2302508..2302687 | + | 180 | WP_028328008.1 | hypothetical protein | - |
A2G07_RS11420 | 2302808..2303584 | + | 777 | WP_010887067.1 | trans-aconitate 2-methyltransferase | - |
A2G07_RS11425 | 2303740..2303964 | + | 225 | WP_162177572.1 | hypothetical protein | - |
A2G07_RS11430 | 2304145..2306613 | - | 2469 | WP_010887065.1 | ATP-dependent helicase HrpB | - |
A2G07_RS11435 | 2306610..2307023 | - | 414 | WP_010887064.1 | type II toxin-antitoxin system VapC family toxin | - |
A2G07_RS11440 | 2307020..2307244 | - | 225 | WP_162177573.1 | hypothetical protein | Antitoxin |
A2G07_RS11445 | 2307297..2307650 | - | 354 | WP_010887062.1 | endoribonuclease MazF | Toxin |
A2G07_RS11450 | 2307644..2307886 | - | 243 | WP_010887061.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
A2G07_RS11455 | 2308066..2309547 | + | 1482 | Protein_2261 | carboxylesterase/lipase family protein | - |
A2G07_RS11460 | 2309595..2310224 | - | 630 | WP_027479568.1 | HAD family hydrolase | - |
A2G07_RS11465 | 2310226..2310405 | - | 180 | WP_034349506.1 | hypothetical protein | - |
A2G07_RS11470 | 2310428..2311390 | - | 963 | WP_034349507.1 | NAD(P)/FAD-dependent oxidoreductase | - |
A2G07_RS11475 | 2311411..2312094 | - | 684 | WP_010887056.1 | SDR family oxidoreductase | - |
A2G07_RS11480 | 2312091..2312462 | - | 372 | Protein_2266 | inorganic pyrophosphatase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 118 a.a. Molecular weight: 12450.24 Da Isoelectric Point: 7.3219
>T62284 WP_010887062.1 NZ_CP015081:c2307650-2307297 [Deinococcus radiodurans R1]
MVSDYVPDAGHLVWLNFTPQAGHEQGGRRPALVLSPAAYNGVTGLMQACPVTSRAKGYPFEVTLPAHLGVSGVVLADHCR
SLDWRSRRAEQLAEAPADVLAEVRGKLGSLLGMSEKA
MVSDYVPDAGHLVWLNFTPQAGHEQGGRRPALVLSPAAYNGVTGLMQACPVTSRAKGYPFEVTLPAHLGVSGVVLADHCR
SLDWRSRRAEQLAEAPADVLAEVRGKLGSLLGMSEKA
Download Length: 354 bp
>T62284 NZ_CP015081:c2307650-2307297 [Deinococcus radiodurans R1]
ATGGTAAGCGATTATGTCCCGGACGCTGGGCATCTGGTGTGGCTCAACTTCACACCTCAGGCAGGGCATGAACAGGGGGG
ACGGCGACCGGCGCTGGTGCTTTCGCCTGCCGCTTATAACGGCGTCACTGGACTGATGCAGGCGTGTCCGGTGACCAGCC
GCGCCAAGGGGTATCCGTTTGAAGTGACGCTCCCTGCTCACCTTGGAGTCAGCGGCGTGGTGCTGGCCGACCATTGCCGC
AGCCTCGACTGGCGCAGTCGCCGGGCCGAACAACTTGCGGAGGCGCCGGCGGACGTCCTGGCCGAAGTCCGTGGCAAGTT
GGGCAGCTTGCTGGGCATGTCCGAGAAGGCATGA
ATGGTAAGCGATTATGTCCCGGACGCTGGGCATCTGGTGTGGCTCAACTTCACACCTCAGGCAGGGCATGAACAGGGGGG
ACGGCGACCGGCGCTGGTGCTTTCGCCTGCCGCTTATAACGGCGTCACTGGACTGATGCAGGCGTGTCCGGTGACCAGCC
GCGCCAAGGGGTATCCGTTTGAAGTGACGCTCCCTGCTCACCTTGGAGTCAGCGGCGTGGTGCTGGCCGACCATTGCCGC
AGCCTCGACTGGCGCAGTCGCCGGGCCGAACAACTTGCGGAGGCGCCGGCGGACGTCCTGGCCGAAGTCCGTGGCAAGTT
GGGCAGCTTGCTGGGCATGTCCGAGAAGGCATGA
Antitoxin
Download Length: 75 a.a. Molecular weight: 8229.23 Da Isoelectric Point: 4.3481
>AT62284 WP_162177573.1 NZ_CP015081:c2307244-2307020 [Deinococcus radiodurans R1]
MTTLEARIENGKVVLTPEQAAELGLREGEVLPVTIAPHEAETEGNPFTRWIGTLPPLPDGEESARFYRRLRDGE
MTTLEARIENGKVVLTPEQAAELGLREGEVLPVTIAPHEAETEGNPFTRWIGTLPPLPDGEESARFYRRLRDGE
Download Length: 225 bp
>AT62284 NZ_CP015081:c2307244-2307020 [Deinococcus radiodurans R1]
ATGACGACGTTGGAGGCCCGGATTGAGAACGGCAAGGTGGTGCTCACCCCTGAGCAGGCCGCCGAACTGGGCCTGCGCGA
AGGCGAAGTGCTGCCGGTGACGATTGCGCCGCACGAAGCGGAAACGGAAGGCAACCCCTTCACCCGCTGGATTGGGACGC
TCCCCCCACTGCCTGACGGTGAAGAGTCTGCGCGGTTCTACCGCCGCCTGCGAGACGGCGAATGA
ATGACGACGTTGGAGGCCCGGATTGAGAACGGCAAGGTGGTGCTCACCCCTGAGCAGGCCGCCGAACTGGGCCTGCGCGA
AGGCGAAGTGCTGCCGGTGACGATTGCGCCGCACGAAGCGGAAACGGAAGGCAACCCCTTCACCCGCTGGATTGGGACGC
TCCCCCCACTGCCTGACGGTGAAGAGTCTGCGCGGTTCTACCGCCGCCTGCGAGACGGCGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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