Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 1075577..1076079 Replicon chromosome
Accession NZ_CP015080
Organism Desulfuromonas sp. DDH964

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DBW_RS18055 Protein ID WP_082820184.1
Coordinates 1075825..1076079 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag DBW_RS18050 Protein ID WP_082820183.1
Coordinates 1075577..1075828 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DBW_RS18045 1070730..1070900 + 171 WP_082820182.1 DUF4177 domain-containing protein -
DBW_RS04770 1070907..1071086 - 180 WP_066725013.1 hypothetical protein -
DBW_RS04775 1071219..1072184 - 966 WP_066725016.1 tryptophan--tRNA ligase -
DBW_RS04780 1072417..1073190 - 774 WP_066725019.1 hypothetical protein -
DBW_RS04785 1073340..1074581 + 1242 WP_066725022.1 GGDEF domain-containing protein -
DBW_RS04790 1074591..1075016 - 426 WP_066725025.1 EamA family transporter -
DBW_RS04795 1075073..1075375 - 303 WP_066725028.1 (2Fe-2S) ferredoxin domain-containing protein -
DBW_RS18050 1075577..1075828 + 252 WP_082820183.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DBW_RS18055 1075825..1076079 + 255 WP_082820184.1 Txe/YoeB family addiction module toxin Toxin
DBW_RS04800 1076143..1077099 - 957 Protein_969 IS1595 family transposase -
DBW_RS18405 1077573..1077878 - 306 WP_157471772.1 hypothetical protein -
DBW_RS04805 1078166..1078405 - 240 WP_066725031.1 hypothetical protein -
DBW_RS04810 1078658..1079866 + 1209 WP_082820464.1 IS256 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10094.54 Da        Isoelectric Point: 9.6591

>T62276 WP_082820184.1 NZ_CP015080:1075825-1076079 [Desulfuromonas sp. DDH964]
MKLIFSENSWEDYQYWVQTDQKILKRVNALIQDIQRSPLSGIGKPEPLKHGLSGYWSRRINDEHRIVYKIVNDSIFIAQV
RYHY

Download         Length: 255 bp

>T62276 NZ_CP015080:1075825-1076079 [Desulfuromonas sp. DDH964]
TTGAAGCTGATATTTTCCGAAAATTCCTGGGAAGATTACCAATATTGGGTACAAACTGATCAAAAAATCCTCAAGCGGGT
GAATGCTTTGATTCAGGATATTCAGCGTTCGCCTCTTTCTGGTATCGGGAAGCCTGAACCTTTGAAGCATGGCTTATCGG
GTTATTGGTCTCGTCGAATCAATGATGAGCACAGAATCGTTTATAAAATTGTAAATGATTCAATATTTATCGCCCAAGTT
CGATACCATTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9374.66 Da        Isoelectric Point: 4.6258

>AT62276 WP_082820183.1 NZ_CP015080:1075577-1075828 [Desulfuromonas sp. DDH964]
MDAITYTSARSNLAKTMEKVCEDHDPVIITRRNESSVVMMSLEDFQALEETAYLLRSPKNVRRLLESIAQLETGGGTERE
LTL

Download         Length: 252 bp

>AT62276 NZ_CP015080:1075577-1075828 [Desulfuromonas sp. DDH964]
ATGGATGCAATTACATATACCAGTGCACGAAGTAACTTAGCAAAAACAATGGAAAAAGTGTGCGAGGATCATGACCCGGT
CATTATCACGCGCCGCAATGAAAGCTCAGTTGTCATGATGTCTCTTGAAGACTTTCAAGCTCTTGAAGAGACTGCTTACT
TACTGAGAAGCCCCAAAAATGTTCGACGCCTTCTCGAGTCAATTGCTCAACTTGAAACAGGTGGTGGCACCGAGCGGGAG
CTTACCCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References