Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 616477..616745 Replicon chromosome
Accession NZ_CP015069
Organism Escherichia coli strain Ecol_743

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 616515..616617 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 616477..616745 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A4R39_RS03135 613635..615074 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
A4R39_RS03140 615191..615427 + 237 WP_001295499.1 DUF1480 family protein -
A4R39_RS03145 615532..615723 + 192 WP_001296140.1 YebW family protein -
A4R39_RS03150 615724..616380 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 616477..616745 + 269 - - Antitoxin
- 616515..616617 - 103 - - Toxin
A4R39_RS03160 616775..617116 - 342 WP_000976472.1 YebY family protein -
A4R39_RS03165 617129..618001 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
A4R39_RS03170 618005..618379 - 375 WP_000168747.1 CopC domain-containing protein YobA -
A4R39_RS03175 618518..618748 + 231 WP_000916763.1 DNA polymerase III subunit theta -
A4R39_RS03180 618850..619506 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
A4R39_RS03185 619530..620192 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T62167 NZ_CP015069:c616617-616515 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT62167 NZ_CP015069:616477-616745 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References