Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 46666..47324 Replicon plasmid pRGUI02
Accession NZ_CP015041
Organism Rhodovulum sp. P5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RGUI_RS20485 Protein ID WP_081536324.1
Coordinates 46917..47324 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RGUI_RS20480 Protein ID WP_081536344.1
Coordinates 46666..46920 (+) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RGUI_RS20460 42249..42746 + 498 WP_081536321.1 twin-arginine translocation pathway signal -
RGUI_RS20465 42821..43333 + 513 WP_081536322.1 ferric reductase-like transmembrane domain-containing protein -
RGUI_RS20470 43706..44422 + 717 WP_081536343.1 c-type cytochrome -
RGUI_RS20475 44485..45750 + 1266 WP_081536323.1 NAD(P)/FAD-dependent oxidoreductase -
RGUI_RS21620 46125..46295 + 171 WP_156883123.1 hypothetical protein -
RGUI_RS20480 46666..46920 + 255 WP_081536344.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
RGUI_RS20485 46917..47324 + 408 WP_081536324.1 type II toxin-antitoxin system VapC family toxin Toxin
RGUI_RS20490 47392..48858 - 1467 WP_156883128.1 xylulokinase -
RGUI_RS20495 48919..49191 - 273 WP_172841231.1 hypothetical protein -
RGUI_RS20500 49259..50737 - 1479 WP_081536327.1 mannitol dehydrogenase family protein -
RGUI_RS20505 50766..51539 - 774 WP_081536328.1 L-iditol 2-dehydrogenase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..67286 67286


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-118)

Antitoxin

(2-50)


Sequences


Toxin        


Download         Length: 136 a.a.        Molecular weight: 14603.62 Da        Isoelectric Point: 4.6805

>T62152 WP_081536324.1 NZ_CP015041:46917-47324 [Rhodovulum sp. P5]
MILLDTNVLSALRRPERAEQVARWLRAQPDDALFLSVVTIGEIERGIALQAPKNPDFARDLADWLSATMDYYADRILDFG
AAEARIWGRLSAEIGSAGADLMIAATALHHGAAVATRNVTDFRPTGVAVIDPFAG

Download         Length: 408 bp

>T62152 NZ_CP015041:46917-47324 [Rhodovulum sp. P5]
ATGATCCTGCTCGATACCAATGTGCTCTCCGCCCTGCGGCGACCGGAGCGCGCGGAGCAGGTCGCCCGTTGGCTTCGGGC
ACAACCCGATGACGCGCTTTTCCTAAGTGTCGTGACGATCGGCGAGATCGAACGCGGCATCGCCCTGCAGGCGCCGAAGA
ACCCGGATTTCGCCCGCGACTTGGCCGACTGGCTGTCGGCGACGATGGACTATTACGCGGATCGCATTCTCGACTTCGGC
GCGGCCGAGGCCCGCATCTGGGGGCGCCTCTCTGCAGAGATCGGCTCGGCCGGCGCCGATCTGATGATTGCCGCCACGGC
GTTGCATCATGGCGCGGCCGTTGCCACCCGGAACGTGACGGATTTTCGGCCAACCGGTGTCGCGGTGATCGATCCCTTCG
CGGGTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9252.54 Da        Isoelectric Point: 7.2037

>AT62152 WP_081536344.1 NZ_CP015041:46666-46920 [Rhodovulum sp. P5]
MWTLHDAKNRFSEVVNAALAGTPQEISRRGKPAVVVLSASAYADMKARVTAERPSFAEHLARFPGMGDDDLPRLEARMRD
LDLG

Download         Length: 255 bp

>AT62152 NZ_CP015041:46666-46920 [Rhodovulum sp. P5]
ATGTGGACACTTCACGATGCCAAGAACCGGTTCAGCGAGGTGGTGAACGCCGCCCTTGCCGGCACGCCGCAGGAAATCTC
CCGGCGCGGCAAGCCCGCGGTCGTCGTCCTGTCGGCCAGCGCCTATGCCGATATGAAGGCGCGCGTGACGGCCGAGCGGC
CGAGCTTTGCCGAGCATCTGGCGCGGTTTCCGGGCATGGGGGATGACGACCTCCCGCGGCTTGAGGCACGGATGCGCGAC
CTCGACCTCGGATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References