Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-Phd |
Location | 46666..47324 | Replicon | plasmid pRGUI02 |
Accession | NZ_CP015041 | ||
Organism | Rhodovulum sp. P5 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | RGUI_RS20485 | Protein ID | WP_081536324.1 |
Coordinates | 46917..47324 (+) | Length | 136 a.a. |
Antitoxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | RGUI_RS20480 | Protein ID | WP_081536344.1 |
Coordinates | 46666..46920 (+) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
RGUI_RS20460 | 42249..42746 | + | 498 | WP_081536321.1 | twin-arginine translocation pathway signal | - |
RGUI_RS20465 | 42821..43333 | + | 513 | WP_081536322.1 | ferric reductase-like transmembrane domain-containing protein | - |
RGUI_RS20470 | 43706..44422 | + | 717 | WP_081536343.1 | c-type cytochrome | - |
RGUI_RS20475 | 44485..45750 | + | 1266 | WP_081536323.1 | NAD(P)/FAD-dependent oxidoreductase | - |
RGUI_RS21620 | 46125..46295 | + | 171 | WP_156883123.1 | hypothetical protein | - |
RGUI_RS20480 | 46666..46920 | + | 255 | WP_081536344.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
RGUI_RS20485 | 46917..47324 | + | 408 | WP_081536324.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
RGUI_RS20490 | 47392..48858 | - | 1467 | WP_156883128.1 | xylulokinase | - |
RGUI_RS20495 | 48919..49191 | - | 273 | WP_172841231.1 | hypothetical protein | - |
RGUI_RS20500 | 49259..50737 | - | 1479 | WP_081536327.1 | mannitol dehydrogenase family protein | - |
RGUI_RS20505 | 50766..51539 | - | 774 | WP_081536328.1 | L-iditol 2-dehydrogenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..67286 | 67286 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 136 a.a. Molecular weight: 14603.62 Da Isoelectric Point: 4.6805
>T62152 WP_081536324.1 NZ_CP015041:46917-47324 [Rhodovulum sp. P5]
MILLDTNVLSALRRPERAEQVARWLRAQPDDALFLSVVTIGEIERGIALQAPKNPDFARDLADWLSATMDYYADRILDFG
AAEARIWGRLSAEIGSAGADLMIAATALHHGAAVATRNVTDFRPTGVAVIDPFAG
MILLDTNVLSALRRPERAEQVARWLRAQPDDALFLSVVTIGEIERGIALQAPKNPDFARDLADWLSATMDYYADRILDFG
AAEARIWGRLSAEIGSAGADLMIAATALHHGAAVATRNVTDFRPTGVAVIDPFAG
Download Length: 408 bp
>T62152 NZ_CP015041:46917-47324 [Rhodovulum sp. P5]
ATGATCCTGCTCGATACCAATGTGCTCTCCGCCCTGCGGCGACCGGAGCGCGCGGAGCAGGTCGCCCGTTGGCTTCGGGC
ACAACCCGATGACGCGCTTTTCCTAAGTGTCGTGACGATCGGCGAGATCGAACGCGGCATCGCCCTGCAGGCGCCGAAGA
ACCCGGATTTCGCCCGCGACTTGGCCGACTGGCTGTCGGCGACGATGGACTATTACGCGGATCGCATTCTCGACTTCGGC
GCGGCCGAGGCCCGCATCTGGGGGCGCCTCTCTGCAGAGATCGGCTCGGCCGGCGCCGATCTGATGATTGCCGCCACGGC
GTTGCATCATGGCGCGGCCGTTGCCACCCGGAACGTGACGGATTTTCGGCCAACCGGTGTCGCGGTGATCGATCCCTTCG
CGGGTTGA
ATGATCCTGCTCGATACCAATGTGCTCTCCGCCCTGCGGCGACCGGAGCGCGCGGAGCAGGTCGCCCGTTGGCTTCGGGC
ACAACCCGATGACGCGCTTTTCCTAAGTGTCGTGACGATCGGCGAGATCGAACGCGGCATCGCCCTGCAGGCGCCGAAGA
ACCCGGATTTCGCCCGCGACTTGGCCGACTGGCTGTCGGCGACGATGGACTATTACGCGGATCGCATTCTCGACTTCGGC
GCGGCCGAGGCCCGCATCTGGGGGCGCCTCTCTGCAGAGATCGGCTCGGCCGGCGCCGATCTGATGATTGCCGCCACGGC
GTTGCATCATGGCGCGGCCGTTGCCACCCGGAACGTGACGGATTTTCGGCCAACCGGTGTCGCGGTGATCGATCCCTTCG
CGGGTTGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9252.54 Da Isoelectric Point: 7.2037
>AT62152 WP_081536344.1 NZ_CP015041:46666-46920 [Rhodovulum sp. P5]
MWTLHDAKNRFSEVVNAALAGTPQEISRRGKPAVVVLSASAYADMKARVTAERPSFAEHLARFPGMGDDDLPRLEARMRD
LDLG
MWTLHDAKNRFSEVVNAALAGTPQEISRRGKPAVVVLSASAYADMKARVTAERPSFAEHLARFPGMGDDDLPRLEARMRD
LDLG
Download Length: 255 bp
>AT62152 NZ_CP015041:46666-46920 [Rhodovulum sp. P5]
ATGTGGACACTTCACGATGCCAAGAACCGGTTCAGCGAGGTGGTGAACGCCGCCCTTGCCGGCACGCCGCAGGAAATCTC
CCGGCGCGGCAAGCCCGCGGTCGTCGTCCTGTCGGCCAGCGCCTATGCCGATATGAAGGCGCGCGTGACGGCCGAGCGGC
CGAGCTTTGCCGAGCATCTGGCGCGGTTTCCGGGCATGGGGGATGACGACCTCCCGCGGCTTGAGGCACGGATGCGCGAC
CTCGACCTCGGATGA
ATGTGGACACTTCACGATGCCAAGAACCGGTTCAGCGAGGTGGTGAACGCCGCCCTTGCCGGCACGCCGCAGGAAATCTC
CCGGCGCGGCAAGCCCGCGGTCGTCGTCCTGTCGGCCAGCGCCTATGCCGATATGAAGGCGCGCGTGACGGCCGAGCGGC
CGAGCTTTGCCGAGCATCTGGCGCGGTTTCCGGGCATGGGGGATGACGACCTCCCGCGGCTTGAGGCACGGATGCGCGAC
CTCGACCTCGGATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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