Detailed information of TA system TA062149

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 4006853..4007327
• Replicon: chromosome
• Accession: NZ_CP015039
• Organism: Rhodovulum sp. P5

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: RGUI_RS19020
• Protein ID: WP_081535768.1
• Coordinates: 4007058..4007327 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: RGUI_RS19015
• Protein ID: WP_081536179.1
• Coordinates: 4006853..4007068 (-)
• Length: 72 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RGUI_RS19000	4002344..4002919	-	576	WP_081535762.1	VPLPA-CTERM sorting domain-containing protein	-
RGUI_RS19005	4003066..4005360	-	2295	WP_172841203.1	AMP-binding protein	-
RGUI_RS19010	4005735..4005941	-	207	WP_081535766.1	cold-shock protein	-
RGUI_RS21575	4006157..4006552	-	396	WP_156883030.1	hypothetical protein	-
RGUI_RS19015	4006853..4007068	-	216	WP_081536179.1	CopG family transcriptional regulator	Antitoxin
RGUI_RS19020	4007058..4007327	-	270	WP_081535768.1	BrnT family toxin	Toxin
RGUI_RS19025	4007378..4009033	-	1656	WP_081535769.1	energy-dependent translational throttle protein EttA	-
RGUI_RS19030	4009168..4009812	-	645	WP_081535771.1	VPLPA-CTERM sorting domain-containing protein	-
RGUI_RS19035	4010054..4010662	+	609	WP_081535773.1	nicotinate-nucleotide adenylyltransferase	-
RGUI_RS19040	4010717..4012207	+	1491	WP_081535775.1	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (4-79)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10500.91 Da
• Isoelectric Point: 11.0479

>T62149 WP_081535768.1 NZ_CP015039:c4007327-4007058 [Rhodovulum sp. P5]
MFEFDPTKSATNREKHGIDFEAAQGVWADADRLEIPARTRGEDRFTLIGRLGTRHWTVIFTRRGDRLRLISARRARKEEV
ALYERKDIR

Nucleotide

• Length: 270 bp

>T62149 NZ_CP015039:c4007327-4007058 [Rhodovulum sp. P5]
ATGTTCGAGTTCGACCCGACCAAAAGCGCGACGAACCGCGAGAAGCACGGGATAGACTTCGAGGCGGCGCAGGGCGTTTG
GGCCGATGCCGACCGGCTCGAAATCCCGGCCCGCACCCGTGGTGAGGACAGGTTCACCCTGATCGGCCGGCTCGGCACAC
GGCACTGGACGGTCATCTTCACCCGGCGCGGCGACCGTCTCAGGCTGATCTCGGCCCGCCGGGCCCGGAAAGAGGAGGTG
GCGCTCTATGAACGCAAAGATATCCGCTGA

Antitoxin

Protein

• Length: 72 a.a.
• Molecular weight: 8124.16 Da
• Isoelectric Point: 4.6005

>AT62149 WP_081536179.1 NZ_CP015039:c4007068-4006853 [Rhodovulum sp. P5]
ISAEEFDRAFDEGEDITAYLDLDKAHRPGRDPRRVNVDFPAWMVDGLDARAAHLGITRQALIKMWIAEKLE

Nucleotide

• Length: 216 bp

>AT62149 NZ_CP015039:c4007068-4006853 [Rhodovulum sp. P5]
ATATCCGCTGAAGAGTTCGACCGCGCCTTCGACGAAGGCGAGGACATCACGGCCTATCTCGACCTCGACAAGGCCCACCG
CCCGGGGCGCGACCCCCGCCGCGTCAACGTCGATTTCCCCGCCTGGATGGTCGACGGGCTGGACGCCCGCGCCGCCCATC
TGGGCATCACCCGGCAGGCGCTGATCAAGATGTGGATCGCGGAAAAGCTGGAATGA