Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 2720791..2721822 Replicon chromosome
Accession NZ_CP015039
Organism Rhodovulum sp. P5

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag RGUI_RS13165 Protein ID WP_081533639.1
Coordinates 2720791..2721360 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag RGUI_RS13170 Protein ID WP_081533641.1
Coordinates 2721364..2721822 (-) Length 153 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RGUI_RS13145 2715870..2717036 - 1167 WP_156882962.1 hypothetical protein -
RGUI_RS13150 2717033..2717701 - 669 WP_156882963.1 hypothetical protein -
RGUI_RS13155 2717698..2719329 - 1632 WP_081533635.1 adenylosuccinate synthetase -
RGUI_RS13160 2719330..2720586 - 1257 WP_172841146.1 macro domain-containing protein -
RGUI_RS13165 2720791..2721360 - 570 WP_081533639.1 PIN domain-containing protein Toxin
RGUI_RS13170 2721364..2721822 - 459 WP_081533641.1 helix-turn-helix domain-containing protein Antitoxin
RGUI_RS13175 2722002..2725304 - 3303 WP_081533643.1 DEAD/DEAH box helicase -
RGUI_RS13180 2725297..2726085 - 789 WP_081533645.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2714661..2757718 43057


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-113)

Antitoxin

SinI-like, DNA-binding domain

(83-127)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21674.45 Da        Isoelectric Point: 4.6590

>T62148 WP_081533639.1 NZ_CP015039:c2721360-2720791 [Rhodovulum sp. P5]
MDRFTALLDANVIYPVGLRDLLLRLADRNLYRVRWSEIIHDEWTRNVLKDRPDLTADKLQRTRETMDRHFPDAVVVGFEP
LIDGLTLPDADDRHVLAAAIRGRADVIVTQNLKDFPQEELDPYEIEAQHPDDFAFSLFDLYPGAVLGAVRDHRAALKRQP
RSSEEHIEAYEGMGMTKFASAIQDYSDVL

Download         Length: 570 bp

>T62148 NZ_CP015039:c2721360-2720791 [Rhodovulum sp. P5]
ATGGACCGGTTCACTGCGTTACTGGACGCCAACGTCATCTATCCGGTCGGCCTGCGCGATTTGCTCCTACGCCTCGCTGA
TCGCAATCTCTACCGCGTTCGCTGGAGTGAGATCATCCACGACGAATGGACGAGAAATGTGCTGAAGGACCGACCTGACC
TAACCGCCGATAAACTTCAACGAACCAGAGAGACCATGGATCGGCATTTCCCCGATGCGGTGGTTGTGGGGTTCGAGCCG
CTGATTGATGGCTTGACGCTTCCCGATGCAGACGATCGGCACGTTCTTGCAGCAGCGATCAGGGGCCGAGCTGATGTCAT
CGTCACACAGAATTTGAAGGACTTCCCGCAGGAAGAGCTCGACCCCTACGAGATTGAAGCTCAGCATCCAGATGATTTCG
CTTTCAGTTTGTTCGATCTTTACCCGGGCGCTGTTCTCGGAGCGGTTCGAGACCACAGGGCTGCGCTAAAGCGGCAACCC
CGAAGCTCTGAGGAGCATATCGAAGCTTATGAAGGAATGGGCATGACCAAATTTGCTTCGGCAATCCAGGATTATTCGGA
TGTCTTATAG

Antitoxin


Download         Length: 153 a.a.        Molecular weight: 16821.28 Da        Isoelectric Point: 6.0121

>AT62148 WP_081533641.1 NZ_CP015039:c2721822-2721364 [Rhodovulum sp. P5]
MNLAVLKEAELVMPTDKESALAAETGRQIASIINGAETVRAHFGSKGAATVDLPVAAVRLLLDILEQMARGNAVTLMPVH
AELTTQQAADLLNVSRTHLVQLLDEEKIPHRKVGTHRRVRAEDVLTYRRETERARRKALDELTELDEELGLQ

Download         Length: 459 bp

>AT62148 NZ_CP015039:c2721822-2721364 [Rhodovulum sp. P5]
ATGAACCTCGCGGTCTTGAAGGAAGCCGAACTGGTCATGCCGACCGATAAGGAATCGGCGCTTGCGGCGGAGACGGGTCG
TCAAATTGCGTCCATCATCAACGGCGCAGAAACCGTGCGTGCGCATTTTGGCTCAAAGGGTGCCGCAACCGTCGACTTGC
CGGTTGCAGCGGTGCGGCTGCTCCTCGACATCCTTGAGCAGATGGCGCGCGGCAATGCAGTAACGCTTATGCCCGTTCAT
GCGGAGCTGACGACGCAGCAAGCGGCCGATTTGCTCAATGTTTCGCGGACCCATCTCGTGCAGCTTCTCGATGAAGAAAA
GATCCCACACCGAAAGGTTGGCACGCACCGACGGGTTCGGGCCGAAGATGTTCTTACCTACCGCCGCGAGACAGAGCGGG
CGCGTCGCAAGGCACTCGATGAACTGACCGAACTCGATGAAGAGCTTGGCCTTCAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References