Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 2720791..2721822 Replicon chromosome
Accession NZ_CP015039
Organism Rhodovulum sp. P5

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag RGUI_RS13165 Protein ID WP_081533639.1
Coordinates 2720791..2721360 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag RGUI_RS13170 Protein ID WP_081533641.1
Coordinates 2721364..2721822 (-) Length 153 a.a.

Genomic Context

RGUI_RS13145RGUI_RS13150RGUI_RS13155RGUI_RS13160RGUI_RS13165RGUI_RS13170RGUI_RS13175RGUI_RS13180
Location: 2715870..2717036 (1167 bp)
Type: Others
Protein ID: WP_156882962.1
Location: 2717033..2717701 (669 bp)
Type: Others
Protein ID: WP_156882963.1
Location: 2717698..2719329 (1632 bp)
Type: Others
Protein ID: WP_081533635.1
Location: 2719330..2720586 (1257 bp)
Type: Others
Protein ID: WP_172841146.1
Location: 2720791..2721360 (570 bp)
Type: Toxin
Protein ID: WP_081533639.1
Location: 2721364..2721822 (459 bp)
Type: Antitoxin
Protein ID: WP_081533641.1
Location: 2722002..2725304 (3303 bp)
Type: Others
Protein ID: WP_081533643.1
Location: 2725297..2726085 (789 bp)
Type: Others
Protein ID: WP_081533645.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
RGUI_RS131452715870..2717036-1167WP_156882962.1hypothetical protein-
RGUI_RS131502717033..2717701-669WP_156882963.1hypothetical protein-
RGUI_RS131552717698..2719329-1632WP_081533635.1adenylosuccinate synthetase-
RGUI_RS131602719330..2720586-1257WP_172841146.1macro domain-containing protein-
RGUI_RS131652720791..2721360-570WP_081533639.1PIN domain-containing proteinToxin
RGUI_RS131702721364..2721822-459WP_081533641.1helix-turn-helix domain-containing proteinAntitoxin
RGUI_RS131752722002..2725304-3303WP_081533643.1DEAD/DEAH box helicase-
RGUI_RS131802725297..2726085-789WP_081533645.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--2714661..275771843057


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-113)

Antitoxin

SinI-like, DNA-binding domain

(83-127)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21674.45 Da        Isoelectric Point: 4.6590

>T62148 WP_081533639.1 NZ_CP015039:c2721360-2720791 [Rhodovulum sp. P5]
MDRFTALLDANVIYPVGLRDLLLRLADRNLYRVRWSEIIHDEWTRNVLKDRPDLTADKLQRTRETMDRHFPDAVVVGFEP
LIDGLTLPDADDRHVLAAAIRGRADVIVTQNLKDFPQEELDPYEIEAQHPDDFAFSLFDLYPGAVLGAVRDHRAALKRQP
RSSEEHIEAYEGMGMTKFASAIQDYSDVL

Download         Length: 570 bp

>T62148 NZ_CP015039:c2721360-2720791 [Rhodovulum sp. P5]
ATGGACCGGTTCACTGCGTTACTGGACGCCAACGTCATCTATCCGGTCGGCCTGCGCGATTTGCTCCTACGCCTCGCTGA
TCGCAATCTCTACCGCGTTCGCTGGAGTGAGATCATCCACGACGAATGGACGAGAAATGTGCTGAAGGACCGACCTGACC
TAACCGCCGATAAACTTCAACGAACCAGAGAGACCATGGATCGGCATTTCCCCGATGCGGTGGTTGTGGGGTTCGAGCCG
CTGATTGATGGCTTGACGCTTCCCGATGCAGACGATCGGCACGTTCTTGCAGCAGCGATCAGGGGCCGAGCTGATGTCAT
CGTCACACAGAATTTGAAGGACTTCCCGCAGGAAGAGCTCGACCCCTACGAGATTGAAGCTCAGCATCCAGATGATTTCG
CTTTCAGTTTGTTCGATCTTTACCCGGGCGCTGTTCTCGGAGCGGTTCGAGACCACAGGGCTGCGCTAAAGCGGCAACCC
CGAAGCTCTGAGGAGCATATCGAAGCTTATGAAGGAATGGGCATGACCAAATTTGCTTCGGCAATCCAGGATTATTCGGA
TGTCTTATAG

Antitoxin


Download         Length: 153 a.a.        Molecular weight: 16821.28 Da        Isoelectric Point: 6.0121

>AT62148 WP_081533641.1 NZ_CP015039:c2721822-2721364 [Rhodovulum sp. P5]
MNLAVLKEAELVMPTDKESALAAETGRQIASIINGAETVRAHFGSKGAATVDLPVAAVRLLLDILEQMARGNAVTLMPVH
AELTTQQAADLLNVSRTHLVQLLDEEKIPHRKVGTHRRVRAEDVLTYRRETERARRKALDELTELDEELGLQ

Download         Length: 459 bp

>AT62148 NZ_CP015039:c2721822-2721364 [Rhodovulum sp. P5]
ATGAACCTCGCGGTCTTGAAGGAAGCCGAACTGGTCATGCCGACCGATAAGGAATCGGCGCTTGCGGCGGAGACGGGTCG
TCAAATTGCGTCCATCATCAACGGCGCAGAAACCGTGCGTGCGCATTTTGGCTCAAAGGGTGCCGCAACCGTCGACTTGC
CGGTTGCAGCGGTGCGGCTGCTCCTCGACATCCTTGAGCAGATGGCGCGCGGCAATGCAGTAACGCTTATGCCCGTTCAT
GCGGAGCTGACGACGCAGCAAGCGGCCGATTTGCTCAATGTTTCGCGGACCCATCTCGTGCAGCTTCTCGATGAAGAAAA
GATCCCACACCGAAAGGTTGGCACGCACCGACGGGTTCGGGCCGAAGATGTTCTTACCTACCGCCGCGAGACAGAGCGGG
CGCGTCGCAAGGCACTCGATGAACTGACCGAACTCGATGAAGAGCTTGGCCTTCAATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References