Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 118198..118818 Replicon chromosome
Accession NZ_CP015036
Organism Burkholderia cenocepacia strain 895

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A3203_RS00540 Protein ID WP_062909989.1
Coordinates 118198..118515 (+) Length 106 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A3203_RS00545 Protein ID WP_006490972.1
Coordinates 118519..118818 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A3203_RS00530 114707..116140 - 1434 WP_006490987.1 aldehyde dehydrogenase family protein -
A3203_RS00535 116169..117809 - 1641 WP_062909988.1 acetolactate synthase large subunit -
A3203_RS00540 118198..118515 + 318 WP_062909989.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A3203_RS00545 118519..118818 + 300 WP_006490972.1 putative addiction module antidote protein Antitoxin
A3203_RS00550 118867..120153 - 1287 WP_006490986.1 DUF445 domain-containing protein -
A3203_RS00555 120250..121470 - 1221 WP_062909990.1 FAD-dependent oxidoreductase -
A3203_RS00560 121460..121786 - 327 WP_006496019.1 non-heme iron oxygenase ferredoxin subunit -
A3203_RS00565 121822..122298 - 477 WP_006490977.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
A3203_RS00570 122314..123585 - 1272 WP_058902844.1 Rieske 2Fe-2S domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(9-100)

Antitoxin

Uncharacterized protein HI1420

(4-96)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11769.52 Da        Isoelectric Point: 8.0598

>T62140 WP_062909989.1 NZ_CP015036:118198-118515 [Burkholderia cenocepacia]
MPYSPPAFSIRTTDVFDAWFAGLPDRLAKRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGPGYRVYDVRRGMIWVILL
CGGDQSAQQADIRAAHAMLAHLDME

Download         Length: 318 bp

>T62140 NZ_CP015036:118198-118515 [Burkholderia cenocepacia]
ATGCCCTACAGTCCTCCTGCATTCAGCATCCGGACCACCGACGTCTTCGACGCCTGGTTTGCCGGCCTGCCCGATCGCCT
CGCCAAACGCCGCATCCAGGCGCGCATCGACCGCCTGTCGATGGGCAATCCGGGCGACTGGAAATCCGCCGGCTCCCCCG
TCGTCGAAATGCGTATCGACCACGGCCCGGGCTATCGCGTCTATGACGTGAGGCGCGGAATGATATGGGTCATCCTGCTC
TGCGGCGGCGATCAATCGGCGCAACAGGCCGACATCCGCGCCGCGCACGCAATGCTCGCGCACCTCGACATGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10608.04 Da        Isoelectric Point: 6.4771

>AT62140 WP_006490972.1 NZ_CP015036:118519-118818 [Burkholderia cenocepacia]
MDKIKTRPWDSAEHLKTEDDMADYFDACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKAAA

Download         Length: 300 bp

>AT62140 NZ_CP015036:118519-118818 [Burkholderia cenocepacia]
ATGGACAAGATCAAGACGCGGCCGTGGGATTCGGCCGAACACCTGAAAACCGAAGACGACATGGCCGACTACTTCGACGC
ATGCCTGCAGGAGGCCGGCGACGATCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGCGCACGCGGCATGTCGC
AGGTCGCACGCGATGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAAGTCATCAAAGCGCTCGGCCTGCAATTGCACGGCGCCAAGGCTGCCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References