Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2071683..2072291 Replicon chromosome
Accession NZ_CP015034
Organism Burkholderia cenocepacia strain 842

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A2T82_RS26330 Protein ID WP_062885380.1
Coordinates 2071986..2072291 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A2T82_RS26325 Protein ID WP_062885379.1
Coordinates 2071683..2071982 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A2T82_RS26300 2066903..2068174 + 1272 WP_006496020.1 Rieske 2Fe-2S domain-containing protein -
A2T82_RS26305 2068190..2068666 + 477 WP_006490977.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
A2T82_RS26310 2068702..2069028 + 327 WP_006496019.1 non-heme iron oxygenase ferredoxin subunit -
A2T82_RS26315 2069018..2070238 + 1221 WP_062885378.1 FAD-dependent oxidoreductase -
A2T82_RS26320 2070348..2071634 + 1287 WP_006490986.1 DUF445 domain-containing protein -
A2T82_RS26325 2071683..2071982 - 300 WP_062885379.1 putative addiction module antidote protein Antitoxin
A2T82_RS26330 2071986..2072291 - 306 WP_062885380.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A2T82_RS26335 2072680..2074320 + 1641 WP_006490980.1 acetolactate synthase large subunit -
A2T82_RS26340 2074349..2075782 + 1434 WP_006490987.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(9-98)

Antitoxin

Uncharacterized protein HI1420

(4-97)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11368.94 Da        Isoelectric Point: 7.2755

>T62137 WP_062885380.1 NZ_CP015034:c2072291-2071986 [Burkholderia cenocepacia]
MPYSPPAFSIRTTDVFDAWFASLPDRRIQARIDRLSMGNPGDWKSAGSPVVEMRIDHGSGYRVYYVRRGTIWVILLCGGD
QSTQQADIRAAHAMLAHLDME

Download         Length: 306 bp

>T62137 NZ_CP015034:c2072291-2071986 [Burkholderia cenocepacia]
ATGCCCTACAGTCCTCCTGCATTCAGCATCCGGACCACCGACGTCTTCGACGCCTGGTTTGCCAGCCTGCCCGATCGCCG
CATCCAGGCGCGCATCGACCGCCTGTCGATGGGCAATCCGGGCGACTGGAAATCCGCCGGCTCCCCCGTGGTCGAAATGC
GTATCGACCACGGCTCGGGCTATCGCGTCTATTACGTGAGGCGCGGAACGATATGGGTCATCCTGCTGTGCGGCGGCGAT
CAATCGACGCAACAGGCCGACATCCGCGCCGCGCACGCAATGCTCGCGCACCTCGACATGGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10622.07 Da        Isoelectric Point: 6.4771

>AT62137 WP_062885379.1 NZ_CP015034:c2071982-2071683 [Burkholderia cenocepacia]
MDKIKTRPWDSAEHLKTEDDMADYFDACLQEAGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHAAKAAA

Download         Length: 300 bp

>AT62137 NZ_CP015034:c2071982-2071683 [Burkholderia cenocepacia]
ATGGACAAGATCAAGACGCGGCCGTGGGATTCGGCCGAACACCTGAAAACCGAAGACGACATGGCCGACTACTTCGACGC
ATGCCTGCAGGAGGCCGGCGACGATCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGCGCACGCGGCATGTCGC
AGGTCGCACGCGATGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAAGTCATCAAGGCGCTCGGCCTGCAATTGCACGCCGCCAAGGCTGCCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References