Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 49106..49377 Replicon chromosome
Accession NZ_CP015020
Organism Escherichia coli strain 28RC1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 49236..49339 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 49106..49377 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ARC77_RS00240 45661..46323 - 663 WP_000944244.1 exodeoxyribonuclease X -
ARC77_RS00245 46347..47003 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ARC77_RS00250 47105..47335 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ARC77_RS00255 47474..47848 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ARC77_RS00260 47852..48724 + 873 WP_062946120.1 copper homeostasis membrane protein CopD -
ARC77_RS00265 48737..49078 + 342 WP_000976483.1 YebY family protein -
- 49106..49377 - 272 - - Antitoxin
- 49236..49339 + 104 - - Toxin
ARC77_RS00275 49474..50130 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ARC77_RS00280 50131..50322 - 192 WP_001296140.1 YebW family protein -
ARC77_RS00285 50427..50663 - 237 WP_001295499.1 DUF1480 family protein -
ARC77_RS00290 50781..52220 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - nleC 589..65218 64629


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T62030 NZ_CP015020:49236-49339 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT62030 NZ_CP015020:c49377-49106 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References