Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relE-pmenA/ParE(toxin) |
Location | 5970792..5972322 | Replicon | chromosome |
Accession | NZ_CP014947 | ||
Organism | Pseudomonas koreensis strain D26 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A554AGI8 |
Locus tag | AYO71_RS26850 | Protein ID | WP_041477706.1 |
Coordinates | 5970792..5971088 (+) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | pmenA | Uniprot ID | A0A554AGJ5 |
Locus tag | AYO71_RS26855 | Protein ID | WP_041477704.1 |
Coordinates | 5971237..5972322 (+) | Length | 362 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AYO71_RS26820 | 5966346..5966807 | + | 462 | WP_016773002.1 | GNAT family N-acetyltransferase | - |
AYO71_RS26825 | 5967067..5967717 | + | 651 | WP_016773001.1 | DedA family protein | - |
AYO71_RS26830 | 5967722..5968534 | + | 813 | WP_041477708.1 | zinc-dependent peptidase | - |
AYO71_RS26835 | 5968647..5969174 | + | 528 | WP_003205933.1 | inorganic diphosphatase | - |
AYO71_RS26840 | 5969392..5970138 | + | 747 | WP_041477707.1 | helix-turn-helix transcriptional regulator | - |
AYO71_RS26845 | 5970563..5970802 | + | 240 | WP_039761862.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
AYO71_RS26850 | 5970792..5971088 | + | 297 | WP_041477706.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
AYO71_RS26855 | 5971237..5972322 | + | 1086 | WP_041477704.1 | macro domain-containing protein | Antitoxin |
AYO71_RS26860 | 5972368..5973180 | - | 813 | WP_041477703.1 | DUF2135 domain-containing protein | - |
AYO71_RS26865 | 5973184..5974803 | - | 1620 | WP_041477702.1 | DUF2300 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11667.51 Da Isoelectric Point: 9.6904
>T61912 WP_041477706.1 NZ_CP014947:5970792-5971088 [Pseudomonas koreensis]
MTYELEFDRRALKEWNKLGDTVRQQFKKKLAEVLENPRIEANRLRELPDCYKVKLKSAGYRLIYQVLDHEILVFVVAIGK
REREAAYEVAQDRLPSRT
MTYELEFDRRALKEWNKLGDTVRQQFKKKLAEVLENPRIEANRLRELPDCYKVKLKSAGYRLIYQVLDHEILVFVVAIGK
REREAAYEVAQDRLPSRT
Download Length: 297 bp
>T61912 NZ_CP014947:5970792-5971088 [Pseudomonas koreensis]
ATGACTTATGAGCTTGAGTTTGATCGACGTGCGTTAAAAGAGTGGAACAAGCTGGGCGATACGGTTCGCCAACAGTTCAA
AAAAAAACTGGCTGAGGTCTTGGAGAATCCTCGAATCGAAGCCAATCGGCTTCGCGAGCTACCAGACTGCTATAAAGTGA
AATTGAAAAGCGCCGGTTATCGCTTGATCTATCAGGTACTTGATCACGAAATCCTGGTGTTCGTGGTCGCCATAGGCAAA
CGTGAGCGGGAGGCAGCCTACGAGGTTGCGCAAGATCGCTTGCCATCCCGGACCTGA
ATGACTTATGAGCTTGAGTTTGATCGACGTGCGTTAAAAGAGTGGAACAAGCTGGGCGATACGGTTCGCCAACAGTTCAA
AAAAAAACTGGCTGAGGTCTTGGAGAATCCTCGAATCGAAGCCAATCGGCTTCGCGAGCTACCAGACTGCTATAAAGTGA
AATTGAAAAGCGCCGGTTATCGCTTGATCTATCAGGTACTTGATCACGAAATCCTGGTGTTCGTGGTCGCCATAGGCAAA
CGTGAGCGGGAGGCAGCCTACGAGGTTGCGCAAGATCGCTTGCCATCCCGGACCTGA
Antitoxin
Download Length: 362 a.a. Molecular weight: 40407.38 Da Isoelectric Point: 6.6149
>AT61912 WP_041477704.1 NZ_CP014947:5971237-5972322 [Pseudomonas koreensis]
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAQNYRVYAAACKAGEVETGKMHVTATNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLLENDVKSVAVPPLGAGNGGLKWPEVREQIVEVLGDLDADVLVFEPSNQYLNVAKRAG
VEKLTPARALIAELIRRYWVLGMECSLLEIQKLAWFLERAIEQLPDTENPLNLKFVAHKYGPYANRLEHLLDNLDGSYLH
CDKRISDAGINDVIWFDQDRKAFLQTYLKTEAKAYSQALERTAQLIDGFESPFGMELLATVDWLLSQEGVSATVPALREA
LKHWDGGAGAAARKSKLFDDQALDIALKRLTSSPFRPGLAA
MIRFTQGNLLEAKTEALVNTVNTVGVMGKGIALMFKERFAQNYRVYAAACKAGEVETGKMHVTATNELDGPRWIVNFPTK
RHWRSPSQMAWITEGLHDLRRFLLENDVKSVAVPPLGAGNGGLKWPEVREQIVEVLGDLDADVLVFEPSNQYLNVAKRAG
VEKLTPARALIAELIRRYWVLGMECSLLEIQKLAWFLERAIEQLPDTENPLNLKFVAHKYGPYANRLEHLLDNLDGSYLH
CDKRISDAGINDVIWFDQDRKAFLQTYLKTEAKAYSQALERTAQLIDGFESPFGMELLATVDWLLSQEGVSATVPALREA
LKHWDGGAGAAARKSKLFDDQALDIALKRLTSSPFRPGLAA
Download Length: 1086 bp
>AT61912 NZ_CP014947:5971237-5972322 [Pseudomonas koreensis]
ATGATCAGATTCACCCAAGGCAACCTGCTGGAAGCCAAAACAGAAGCCCTCGTCAACACGGTGAATACCGTAGGCGTGAT
GGGCAAGGGCATCGCATTGATGTTCAAAGAGCGCTTTGCGCAGAATTACCGCGTGTATGCAGCGGCGTGTAAGGCCGGGG
AAGTAGAAACCGGCAAAATGCATGTGACTGCCACCAACGAACTCGACGGCCCTCGCTGGATCGTGAATTTCCCCACCAAG
CGCCACTGGCGGTCGCCGTCGCAGATGGCATGGATCACCGAGGGTTTGCATGACCTGCGGCGGTTCCTGCTTGAAAACGA
TGTGAAATCCGTTGCGGTTCCACCGTTAGGTGCTGGTAACGGCGGTTTGAAGTGGCCTGAAGTCCGTGAACAGATTGTCG
AAGTGTTGGGAGATCTCGATGCTGATGTCTTAGTGTTCGAGCCGTCCAATCAGTACCTGAATGTCGCCAAACGCGCGGGC
GTAGAAAAGCTCACGCCAGCCCGAGCGCTTATCGCCGAACTGATTCGTCGCTACTGGGTTTTAGGCATGGAGTGCAGTCT
GCTGGAGATTCAGAAGCTCGCCTGGTTTCTTGAGCGCGCTATCGAGCAGCTGCCAGATACCGAGAACCCTCTGAACCTGA
AGTTCGTCGCACATAAATATGGCCCATACGCCAACCGGCTTGAACACCTGCTTGATAACCTCGATGGTAGCTATCTGCAC
TGTGACAAGCGCATCAGCGATGCAGGCATTAATGATGTGATCTGGTTTGATCAAGATCGCAAAGCGTTTTTACAAACGTA
TCTCAAGACTGAGGCCAAGGCATATTCGCAAGCGTTGGAACGTACGGCGCAACTGATTGACGGTTTTGAGTCGCCATTCG
GTATGGAGTTATTGGCCACGGTCGATTGGTTGTTGAGCCAGGAAGGGGTATCTGCGACTGTTCCAGCGCTACGCGAAGCA
TTGAAGCATTGGGACGGTGGCGCCGGTGCTGCGGCTCGCAAGAGTAAACTGTTCGATGATCAGGCCCTTGATATTGCGCT
CAAACGCCTGACATCCAGTCCTTTCCGGCCTGGATTAGCGGCCTGA
ATGATCAGATTCACCCAAGGCAACCTGCTGGAAGCCAAAACAGAAGCCCTCGTCAACACGGTGAATACCGTAGGCGTGAT
GGGCAAGGGCATCGCATTGATGTTCAAAGAGCGCTTTGCGCAGAATTACCGCGTGTATGCAGCGGCGTGTAAGGCCGGGG
AAGTAGAAACCGGCAAAATGCATGTGACTGCCACCAACGAACTCGACGGCCCTCGCTGGATCGTGAATTTCCCCACCAAG
CGCCACTGGCGGTCGCCGTCGCAGATGGCATGGATCACCGAGGGTTTGCATGACCTGCGGCGGTTCCTGCTTGAAAACGA
TGTGAAATCCGTTGCGGTTCCACCGTTAGGTGCTGGTAACGGCGGTTTGAAGTGGCCTGAAGTCCGTGAACAGATTGTCG
AAGTGTTGGGAGATCTCGATGCTGATGTCTTAGTGTTCGAGCCGTCCAATCAGTACCTGAATGTCGCCAAACGCGCGGGC
GTAGAAAAGCTCACGCCAGCCCGAGCGCTTATCGCCGAACTGATTCGTCGCTACTGGGTTTTAGGCATGGAGTGCAGTCT
GCTGGAGATTCAGAAGCTCGCCTGGTTTCTTGAGCGCGCTATCGAGCAGCTGCCAGATACCGAGAACCCTCTGAACCTGA
AGTTCGTCGCACATAAATATGGCCCATACGCCAACCGGCTTGAACACCTGCTTGATAACCTCGATGGTAGCTATCTGCAC
TGTGACAAGCGCATCAGCGATGCAGGCATTAATGATGTGATCTGGTTTGATCAAGATCGCAAAGCGTTTTTACAAACGTA
TCTCAAGACTGAGGCCAAGGCATATTCGCAAGCGTTGGAACGTACGGCGCAACTGATTGACGGTTTTGAGTCGCCATTCG
GTATGGAGTTATTGGCCACGGTCGATTGGTTGTTGAGCCAGGAAGGGGTATCTGCGACTGTTCCAGCGCTACGCGAAGCA
TTGAAGCATTGGGACGGTGGCGCCGGTGCTGCGGCTCGCAAGAGTAAACTGTTCGATGATCAGGCCCTTGATATTGCGCT
CAAACGCCTGACATCCAGTCCTTTCCGGCCTGGATTAGCGGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A554AGI8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A554AGJ5 |