Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 3826048..3826576 Replicon chromosome
Accession NZ_CP014947
Organism Pseudomonas koreensis strain D26

Toxin (Protein)


Gene name parE Uniprot ID A0A554AHL9
Locus tag AYO71_RS17115 Protein ID WP_041480302.1
Coordinates 3826286..3826576 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A341F4V9
Locus tag AYO71_RS28915 Protein ID WP_016770738.1
Coordinates 3826048..3826293 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYO71_RS17100 3821792..3823495 + 1704 WP_041480304.1 amidase -
AYO71_RS17105 3823696..3824991 + 1296 WP_041480303.1 OprD family porin -
AYO71_RS17110 3825371..3825706 + 336 WP_041480422.1 hypothetical protein -
AYO71_RS28915 3826048..3826293 + 246 WP_016770738.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
AYO71_RS17115 3826286..3826576 + 291 WP_041480302.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AYO71_RS17120 3826922..3829216 + 2295 WP_052392206.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(8-78)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11136.67 Da        Isoelectric Point: 5.6837

>T61908 WP_041480302.1 NZ_CP014947:3826286-3826576 [Pseudomonas koreensis]
MAEYRLTPAAEADLEAIWTYTAQQWGLDQANRYIDILTESFEQLADRPKTAPACDAIRPGYRRCSVESHMIYFRITAYGI
AIIRILHDRMEAQRNL

Download         Length: 291 bp

>T61908 NZ_CP014947:3826286-3826576 [Pseudomonas koreensis]
ATGGCTGAATACCGACTTACCCCCGCCGCCGAAGCGGATCTTGAGGCTATCTGGACCTATACAGCTCAACAATGGGGTTT
GGATCAGGCCAATCGCTACATCGACATCCTGACTGAGTCCTTCGAGCAGTTGGCTGATCGTCCCAAAACAGCACCCGCAT
GCGACGCTATCCGCCCCGGTTACCGACGCTGCAGCGTGGAGAGTCACATGATTTATTTTCGAATCACCGCCTATGGGATC
GCGATCATCAGAATCTTGCATGACCGGATGGAAGCGCAGCGTAATCTCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9354.43 Da        Isoelectric Point: 7.3193

>AT61908 WP_016770738.1 NZ_CP014947:3826048-3826293 [Pseudomonas koreensis]
MATVRKTITVTDQQDHWIKAQIEAGHYTNDSEYIRDLIRREQERNAELETVRAALREGESSGAPRPFDADAFKKRMLRAH
G

Download         Length: 246 bp

>AT61908 NZ_CP014947:3826048-3826293 [Pseudomonas koreensis]
ATGGCTACCGTACGCAAAACCATAACCGTGACTGACCAGCAAGACCATTGGATCAAAGCTCAAATAGAAGCGGGACATTA
CACCAACGACAGCGAATATATCCGCGATTTGATCCGTCGAGAGCAAGAGCGAAACGCTGAACTGGAAACCGTCCGCGCAG
CCCTTCGAGAAGGAGAATCCAGTGGTGCCCCCCGGCCTTTCGATGCTGATGCTTTCAAAAAGAGAATGTTGAGGGCGCAT
GGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A554AHL9

Antitoxin

Source ID Structure
AlphaFold DB A0A341F4V9

References