Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3353519..3354038 Replicon chromosome
Accession NZ_CP014947
Organism Pseudomonas koreensis strain D26

Toxin (Protein)


Gene name relE Uniprot ID A0A142NAM9
Locus tag AYO71_RS14955 Protein ID WP_039758603.1
Coordinates 3353757..3354038 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1N6YEG7
Locus tag AYO71_RS14950 Protein ID WP_039758605.1
Coordinates 3353519..3353767 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYO71_RS14930 3349110..3350120 + 1011 WP_041478707.1 AAA family ATPase -
AYO71_RS14935 3350093..3350785 + 693 WP_143979040.1 VWA domain-containing protein -
AYO71_RS14940 3351143..3352702 + 1560 WP_041478708.1 TerC family protein -
AYO71_RS14945 3352839..3353270 - 432 WP_041478709.1 thioredoxin family protein -
AYO71_RS14950 3353519..3353767 + 249 WP_039758605.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
AYO71_RS14955 3353757..3354038 + 282 WP_039758603.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AYO71_RS14960 3354319..3355167 + 849 WP_041478710.1 transporter substrate-binding domain-containing protein -
AYO71_RS14965 3355219..3355881 + 663 WP_024012746.1 amino acid ABC transporter permease -
AYO71_RS14970 3355891..3356553 + 663 WP_041478712.1 amino acid ABC transporter permease -
AYO71_RS14975 3356550..3357341 + 792 WP_041478713.1 amino acid ABC transporter ATP-binding protein -
AYO71_RS14980 3357373..3357762 + 390 WP_016774497.1 RidA family protein -
AYO71_RS14985 3357892..3358656 + 765 WP_041478714.1 IclR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10876.71 Da        Isoelectric Point: 10.8793

>T61907 WP_039758603.1 NZ_CP014947:3353757-3354038 [Pseudomonas koreensis]
MTYELEFSEKAWKEWRKLGSELREQFKNKLVERLANPHVPAARLKGLSNAYKIKLRSAGYRLVYRVRDEVLVVTVIAVGK
RQGGDVYRQALKR

Download         Length: 282 bp

>T61907 NZ_CP014947:3353757-3354038 [Pseudomonas koreensis]
ATGACCTATGAACTGGAATTTTCTGAAAAGGCTTGGAAGGAGTGGCGAAAGCTTGGGTCGGAGCTCAGAGAGCAGTTCAA
AAATAAACTTGTTGAAAGGCTGGCAAATCCCCACGTTCCGGCGGCTCGTCTGAAAGGATTGAGTAACGCCTATAAAATCA
AGCTTCGAAGCGCTGGATATCGGTTGGTCTATCGGGTCAGGGACGAGGTACTGGTCGTTACGGTGATAGCGGTCGGAAAA
CGGCAGGGTGGTGATGTCTACAGGCAGGCGCTAAAGCGCTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9043.47 Da        Isoelectric Point: 4.7905

>AT61907 WP_039758605.1 NZ_CP014947:3353519-3353767 [Pseudomonas koreensis]
MTHIVLSHVVASISELKKNPMGTVAAGGGRSVAILNRNEPAFYCVPAKEYEAMMERLEDLELIALCKERENDPTIKVSID
DL

Download         Length: 249 bp

>AT61907 NZ_CP014947:3353519-3353767 [Pseudomonas koreensis]
ATGACGCACATTGTTCTTTCTCACGTCGTAGCGAGTATTTCCGAATTGAAAAAAAACCCTATGGGTACAGTGGCAGCTGG
TGGGGGCCGGTCTGTGGCGATCCTTAATCGAAACGAACCGGCCTTCTACTGTGTTCCTGCCAAGGAATATGAAGCAATGA
TGGAGCGCCTGGAGGATCTGGAACTGATCGCCCTTTGCAAGGAGCGAGAAAACGATCCGACCATCAAGGTATCCATTGAT
GACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A142NAM9

Antitoxin

Source ID Structure
AlphaFold DB A0A1N6YEG7

References