Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-YafN |
Location | 3353519..3354038 | Replicon | chromosome |
Accession | NZ_CP014947 | ||
Organism | Pseudomonas koreensis strain D26 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A142NAM9 |
Locus tag | AYO71_RS14955 | Protein ID | WP_039758603.1 |
Coordinates | 3353757..3354038 (+) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A1N6YEG7 |
Locus tag | AYO71_RS14950 | Protein ID | WP_039758605.1 |
Coordinates | 3353519..3353767 (+) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AYO71_RS14930 | 3349110..3350120 | + | 1011 | WP_041478707.1 | AAA family ATPase | - |
AYO71_RS14935 | 3350093..3350785 | + | 693 | WP_143979040.1 | VWA domain-containing protein | - |
AYO71_RS14940 | 3351143..3352702 | + | 1560 | WP_041478708.1 | TerC family protein | - |
AYO71_RS14945 | 3352839..3353270 | - | 432 | WP_041478709.1 | thioredoxin family protein | - |
AYO71_RS14950 | 3353519..3353767 | + | 249 | WP_039758605.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
AYO71_RS14955 | 3353757..3354038 | + | 282 | WP_039758603.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
AYO71_RS14960 | 3354319..3355167 | + | 849 | WP_041478710.1 | transporter substrate-binding domain-containing protein | - |
AYO71_RS14965 | 3355219..3355881 | + | 663 | WP_024012746.1 | amino acid ABC transporter permease | - |
AYO71_RS14970 | 3355891..3356553 | + | 663 | WP_041478712.1 | amino acid ABC transporter permease | - |
AYO71_RS14975 | 3356550..3357341 | + | 792 | WP_041478713.1 | amino acid ABC transporter ATP-binding protein | - |
AYO71_RS14980 | 3357373..3357762 | + | 390 | WP_016774497.1 | RidA family protein | - |
AYO71_RS14985 | 3357892..3358656 | + | 765 | WP_041478714.1 | IclR family transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10876.71 Da Isoelectric Point: 10.8793
>T61907 WP_039758603.1 NZ_CP014947:3353757-3354038 [Pseudomonas koreensis]
MTYELEFSEKAWKEWRKLGSELREQFKNKLVERLANPHVPAARLKGLSNAYKIKLRSAGYRLVYRVRDEVLVVTVIAVGK
RQGGDVYRQALKR
MTYELEFSEKAWKEWRKLGSELREQFKNKLVERLANPHVPAARLKGLSNAYKIKLRSAGYRLVYRVRDEVLVVTVIAVGK
RQGGDVYRQALKR
Download Length: 282 bp
>T61907 NZ_CP014947:3353757-3354038 [Pseudomonas koreensis]
ATGACCTATGAACTGGAATTTTCTGAAAAGGCTTGGAAGGAGTGGCGAAAGCTTGGGTCGGAGCTCAGAGAGCAGTTCAA
AAATAAACTTGTTGAAAGGCTGGCAAATCCCCACGTTCCGGCGGCTCGTCTGAAAGGATTGAGTAACGCCTATAAAATCA
AGCTTCGAAGCGCTGGATATCGGTTGGTCTATCGGGTCAGGGACGAGGTACTGGTCGTTACGGTGATAGCGGTCGGAAAA
CGGCAGGGTGGTGATGTCTACAGGCAGGCGCTAAAGCGCTGA
ATGACCTATGAACTGGAATTTTCTGAAAAGGCTTGGAAGGAGTGGCGAAAGCTTGGGTCGGAGCTCAGAGAGCAGTTCAA
AAATAAACTTGTTGAAAGGCTGGCAAATCCCCACGTTCCGGCGGCTCGTCTGAAAGGATTGAGTAACGCCTATAAAATCA
AGCTTCGAAGCGCTGGATATCGGTTGGTCTATCGGGTCAGGGACGAGGTACTGGTCGTTACGGTGATAGCGGTCGGAAAA
CGGCAGGGTGGTGATGTCTACAGGCAGGCGCTAAAGCGCTGA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9043.47 Da Isoelectric Point: 4.7905
>AT61907 WP_039758605.1 NZ_CP014947:3353519-3353767 [Pseudomonas koreensis]
MTHIVLSHVVASISELKKNPMGTVAAGGGRSVAILNRNEPAFYCVPAKEYEAMMERLEDLELIALCKERENDPTIKVSID
DL
MTHIVLSHVVASISELKKNPMGTVAAGGGRSVAILNRNEPAFYCVPAKEYEAMMERLEDLELIALCKERENDPTIKVSID
DL
Download Length: 249 bp
>AT61907 NZ_CP014947:3353519-3353767 [Pseudomonas koreensis]
ATGACGCACATTGTTCTTTCTCACGTCGTAGCGAGTATTTCCGAATTGAAAAAAAACCCTATGGGTACAGTGGCAGCTGG
TGGGGGCCGGTCTGTGGCGATCCTTAATCGAAACGAACCGGCCTTCTACTGTGTTCCTGCCAAGGAATATGAAGCAATGA
TGGAGCGCCTGGAGGATCTGGAACTGATCGCCCTTTGCAAGGAGCGAGAAAACGATCCGACCATCAAGGTATCCATTGAT
GACCTATGA
ATGACGCACATTGTTCTTTCTCACGTCGTAGCGAGTATTTCCGAATTGAAAAAAAACCCTATGGGTACAGTGGCAGCTGG
TGGGGGCCGGTCTGTGGCGATCCTTAATCGAAACGAACCGGCCTTCTACTGTGTTCCTGCCAAGGAATATGAAGCAATGA
TGGAGCGCCTGGAGGATCTGGAACTGATCGCCCTTTGCAAGGAGCGAGAAAACGATCCGACCATCAAGGTATCCATTGAT
GACCTATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A142NAM9 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1N6YEG7 |