Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
Location | 2960310..2960859 | Replicon | chromosome |
Accession | NZ_CP014947 | ||
Organism | Pseudomonas koreensis strain D26 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A554AG06 |
Locus tag | AYO71_RS13185 | Protein ID | WP_041478585.1 |
Coordinates | 2960584..2960859 (+) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A554AG13 |
Locus tag | AYO71_RS13180 | Protein ID | WP_041478584.1 |
Coordinates | 2960310..2960582 (+) | Length | 91 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AYO71_RS13160 | 2955740..2956363 | + | 624 | WP_016774080.1 | hydrolase | - |
AYO71_RS13165 | 2956451..2957878 | - | 1428 | WP_041478581.1 | mechanosensitive ion channel family protein | - |
AYO71_RS13170 | 2957987..2959006 | - | 1020 | WP_041478582.1 | alpha/beta hydrolase | - |
AYO71_RS13175 | 2959242..2960141 | + | 900 | WP_041478583.1 | LysR family transcriptional regulator | - |
AYO71_RS13180 | 2960310..2960582 | + | 273 | WP_041478584.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
AYO71_RS13185 | 2960584..2960859 | + | 276 | WP_041478585.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
AYO71_RS13190 | 2960960..2961757 | + | 798 | WP_041478586.1 | class I SAM-dependent methyltransferase | - |
AYO71_RS13195 | 2961884..2962576 | - | 693 | WP_041478587.1 | N-acetyltransferase | - |
AYO71_RS13200 | 2962634..2963425 | - | 792 | WP_041478588.1 | ChbG/HpnK family deacetylase | - |
AYO71_RS13205 | 2963397..2964584 | - | 1188 | WP_041478589.1 | GNAT family N-acetyltransferase | - |
AYO71_RS13210 | 2964589..2965278 | - | 690 | WP_041478590.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10757.44 Da Isoelectric Point: 7.2025
>T61906 WP_041478585.1 NZ_CP014947:2960584-2960859 [Pseudomonas koreensis]
MELKWTSKGLSDLTRLYEFLAAVNQPAAARTVQQLTAAPIMLLANPRLGERLEEFEPRDVRRILVGHYEMRYEIVDSTIY
LLRLWHTREER
MELKWTSKGLSDLTRLYEFLAAVNQPAAARTVQQLTAAPIMLLANPRLGERLEEFEPRDVRRILVGHYEMRYEIVDSTIY
LLRLWHTREER
Download Length: 276 bp
>T61906 NZ_CP014947:2960584-2960859 [Pseudomonas koreensis]
ATGGAGTTGAAGTGGACCAGCAAAGGGCTTTCCGACCTGACCAGGCTTTACGAGTTTTTGGCAGCAGTTAATCAACCTGC
CGCTGCGCGCACTGTGCAACAGCTGACCGCCGCTCCGATAATGCTGCTAGCCAATCCGCGCTTGGGTGAACGTCTGGAAG
AATTTGAACCGCGAGATGTTCGAAGGATTCTGGTCGGGCACTACGAAATGCGCTACGAAATTGTCGATTCGACTATCTAC
CTGCTGCGCCTTTGGCACACTCGCGAAGAGCGATAA
ATGGAGTTGAAGTGGACCAGCAAAGGGCTTTCCGACCTGACCAGGCTTTACGAGTTTTTGGCAGCAGTTAATCAACCTGC
CGCTGCGCGCACTGTGCAACAGCTGACCGCCGCTCCGATAATGCTGCTAGCCAATCCGCGCTTGGGTGAACGTCTGGAAG
AATTTGAACCGCGAGATGTTCGAAGGATTCTGGTCGGGCACTACGAAATGCGCTACGAAATTGTCGATTCGACTATCTAC
CTGCTGCGCCTTTGGCACACTCGCGAAGAGCGATAA
Antitoxin
Download Length: 91 a.a. Molecular weight: 10092.46 Da Isoelectric Point: 5.6994
>AT61906 WP_041478584.1 NZ_CP014947:2960310-2960582 [Pseudomonas koreensis]
MAAPMKTRSVTAHVPVQLAEKVDLMAERLERSRNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQSVQAWADSL
SSDTPLKAPL
MAAPMKTRSVTAHVPVQLAEKVDLMAERLERSRNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQSVQAWADSL
SSDTPLKAPL
Download Length: 273 bp
>AT61906 NZ_CP014947:2960310-2960582 [Pseudomonas koreensis]
ATGGCCGCGCCAATGAAAACCCGATCCGTGACTGCCCATGTACCCGTGCAATTGGCCGAAAAGGTCGATCTGATGGCTGA
GCGTCTGGAACGCTCGCGTAACTGGATTGTGAAACAGGCCCTGAGCGCCTGGATTGATCAAGAGGAAGAGCGCAGCCGTT
TGACGCGCGAAGCCTTGGCTGATGTGGACGCCGGGCGCGTTATCGATCATCAATCAGTGCAGGCATGGGCGGACAGCTTG
AGTTCCGATACGCCTCTCAAGGCTCCACTTTGA
ATGGCCGCGCCAATGAAAACCCGATCCGTGACTGCCCATGTACCCGTGCAATTGGCCGAAAAGGTCGATCTGATGGCTGA
GCGTCTGGAACGCTCGCGTAACTGGATTGTGAAACAGGCCCTGAGCGCCTGGATTGATCAAGAGGAAGAGCGCAGCCGTT
TGACGCGCGAAGCCTTGGCTGATGTGGACGCCGGGCGCGTTATCGATCATCAATCAGTGCAGGCATGGGCGGACAGCTTG
AGTTCCGATACGCCTCTCAAGGCTCCACTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A554AG06 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A554AG13 |