Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2960310..2960859 Replicon chromosome
Accession NZ_CP014947
Organism Pseudomonas koreensis strain D26

Toxin (Protein)


Gene name relE Uniprot ID A0A554AG06
Locus tag AYO71_RS13185 Protein ID WP_041478585.1
Coordinates 2960584..2960859 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A554AG13
Locus tag AYO71_RS13180 Protein ID WP_041478584.1
Coordinates 2960310..2960582 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AYO71_RS13160 2955740..2956363 + 624 WP_016774080.1 hydrolase -
AYO71_RS13165 2956451..2957878 - 1428 WP_041478581.1 mechanosensitive ion channel family protein -
AYO71_RS13170 2957987..2959006 - 1020 WP_041478582.1 alpha/beta hydrolase -
AYO71_RS13175 2959242..2960141 + 900 WP_041478583.1 LysR family transcriptional regulator -
AYO71_RS13180 2960310..2960582 + 273 WP_041478584.1 ribbon-helix-helix domain-containing protein Antitoxin
AYO71_RS13185 2960584..2960859 + 276 WP_041478585.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AYO71_RS13190 2960960..2961757 + 798 WP_041478586.1 class I SAM-dependent methyltransferase -
AYO71_RS13195 2961884..2962576 - 693 WP_041478587.1 N-acetyltransferase -
AYO71_RS13200 2962634..2963425 - 792 WP_041478588.1 ChbG/HpnK family deacetylase -
AYO71_RS13205 2963397..2964584 - 1188 WP_041478589.1 GNAT family N-acetyltransferase -
AYO71_RS13210 2964589..2965278 - 690 WP_041478590.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10757.44 Da        Isoelectric Point: 7.2025

>T61906 WP_041478585.1 NZ_CP014947:2960584-2960859 [Pseudomonas koreensis]
MELKWTSKGLSDLTRLYEFLAAVNQPAAARTVQQLTAAPIMLLANPRLGERLEEFEPRDVRRILVGHYEMRYEIVDSTIY
LLRLWHTREER

Download         Length: 276 bp

>T61906 NZ_CP014947:2960584-2960859 [Pseudomonas koreensis]
ATGGAGTTGAAGTGGACCAGCAAAGGGCTTTCCGACCTGACCAGGCTTTACGAGTTTTTGGCAGCAGTTAATCAACCTGC
CGCTGCGCGCACTGTGCAACAGCTGACCGCCGCTCCGATAATGCTGCTAGCCAATCCGCGCTTGGGTGAACGTCTGGAAG
AATTTGAACCGCGAGATGTTCGAAGGATTCTGGTCGGGCACTACGAAATGCGCTACGAAATTGTCGATTCGACTATCTAC
CTGCTGCGCCTTTGGCACACTCGCGAAGAGCGATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10092.46 Da        Isoelectric Point: 5.6994

>AT61906 WP_041478584.1 NZ_CP014947:2960310-2960582 [Pseudomonas koreensis]
MAAPMKTRSVTAHVPVQLAEKVDLMAERLERSRNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQSVQAWADSL
SSDTPLKAPL

Download         Length: 273 bp

>AT61906 NZ_CP014947:2960310-2960582 [Pseudomonas koreensis]
ATGGCCGCGCCAATGAAAACCCGATCCGTGACTGCCCATGTACCCGTGCAATTGGCCGAAAAGGTCGATCTGATGGCTGA
GCGTCTGGAACGCTCGCGTAACTGGATTGTGAAACAGGCCCTGAGCGCCTGGATTGATCAAGAGGAAGAGCGCAGCCGTT
TGACGCGCGAAGCCTTGGCTGATGTGGACGCCGGGCGCGTTATCGATCATCAATCAGTGCAGGCATGGGCGGACAGCTTG
AGTTCCGATACGCCTCTCAAGGCTCCACTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A554AG06

Antitoxin

Source ID Structure
AlphaFold DB A0A554AG13

References