Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2739184..2739743 Replicon chromosome
Accession NZ_CP014943
Organism Colwellia sp. PAMC 21821

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A3Q33_RS11675 Protein ID WP_081180092.1
Coordinates 2739184..2739462 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A3Q33_RS11680 Protein ID WP_081180093.1
Coordinates 2739459..2739743 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A3Q33_RS11655 2735509..2736475 + 967 WP_155866850.1 IS630 family transposase -
A3Q33_RS11665 2737043..2738101 - 1059 WP_081180091.1 IS91 family transposase -
A3Q33_RS11670 2738098..2738985 - 888 WP_081178441.1 site-specific integrase -
A3Q33_RS11675 2739184..2739462 - 279 WP_081180092.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
A3Q33_RS11680 2739459..2739743 - 285 WP_081180093.1 damage-inducible protein J Antitoxin
A3Q33_RS11685 2739916..2740839 + 924 WP_081180094.1 hypothetical protein -
A3Q33_RS11690 2740909..2742459 - 1551 WP_081180095.1 cryptochrome/photolyase family protein -
A3Q33_RS11695 2742565..2742717 - 153 WP_081180096.1 DUF2256 domain-containing protein -
A3Q33_RS11700 2742733..2744307 - 1575 Protein_2278 deoxyribodipyrimidine photo-lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10894.60 Da        Isoelectric Point: 4.5467

>T61897 WP_081180092.1 NZ_CP014943:c2739462-2739184 [Colwellia sp. PAMC 21821]
MILWEEESLNDREKIFEFLFDFNPSAAEKTDQIIESKVENLLEHPLMGVQRDIFRGRILIIPEVSMIVSYCVDDGTIRIM
RVLHQKQKFPQD

Download         Length: 279 bp

>T61897 NZ_CP014943:c2739462-2739184 [Colwellia sp. PAMC 21821]
ATGATTCTTTGGGAAGAAGAATCACTGAATGACCGTGAAAAGATATTTGAATTCTTATTTGATTTTAACCCTAGCGCAGC
AGAAAAAACCGACCAAATAATTGAGTCTAAAGTTGAAAATTTACTTGAACATCCGTTAATGGGTGTTCAAAGAGATATTT
TTCGTGGACGAATCTTAATTATCCCCGAAGTATCAATGATCGTTTCTTATTGTGTTGATGATGGAACCATCCGTATTATG
CGAGTTTTACACCAGAAGCAGAAGTTTCCGCAAGATTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11088.52 Da        Isoelectric Point: 8.0499

>AT61897 WP_081180093.1 NZ_CP014943:c2739743-2739459 [Colwellia sp. PAMC 21821]
MDTRIQFRVDEETKRLAQLMAESQGRTLSDACRELTVGLAEEQRKTMTHDLWLTEQINAAFDKFDSGKANFMEHNEAKTQ
MEVRKNKIRNRDKR

Download         Length: 285 bp

>AT61897 NZ_CP014943:c2739743-2739459 [Colwellia sp. PAMC 21821]
ATGGACACTCGCATACAATTTAGAGTCGATGAAGAAACTAAACGCTTGGCGCAGTTAATGGCTGAAAGCCAAGGGCGTAC
ATTAAGCGATGCATGTAGAGAGCTTACCGTAGGCTTAGCTGAAGAACAACGAAAAACAATGACCCATGATTTGTGGTTAA
CAGAACAAATAAATGCTGCATTTGATAAATTTGATAGCGGTAAAGCTAATTTTATGGAACACAATGAAGCTAAAACCCAG
ATGGAAGTTAGAAAGAACAAGATCCGTAATAGAGATAAAAGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References