Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 130900..131436 Replicon plasmid unnamed
Accession NZ_CP014942
Organism Rhodococcus sp. BH4

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag A0W34_RS29945 Protein ID WP_042926284.1
Coordinates 130900..131214 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag A0W34_RS29950 Protein ID WP_042926289.1
Coordinates 131215..131436 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A0W34_RS29925 126816..127407 + 592 Protein_127 IS6 family transposase -
A0W34_RS29930 127445..127996 + 552 Protein_128 DUF1016 domain-containing protein -
A0W34_RS29935 128125..128922 - 798 WP_058228359.1 hypothetical protein -
A0W34_RS29940 128922..130877 - 1956 WP_058228366.1 hypothetical protein -
A0W34_RS29945 130900..131214 - 315 WP_042926284.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
A0W34_RS29950 131215..131436 - 222 WP_042926289.1 hypothetical protein Antitoxin
A0W34_RS33260 131620..131967 - 348 WP_063892177.1 hypothetical protein -
A0W34_RS29960 131997..133298 - 1302 WP_058228360.1 AAA family ATPase -
A0W34_RS29965 133369..134556 - 1188 WP_081558947.1 hypothetical protein -
A0W34_RS29970 134553..134747 - 195 WP_081558949.1 hypothetical protein -
A0W34_RS29975 134744..135982 - 1239 WP_081558951.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..704258 704258


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(12-93)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11063.65 Da        Isoelectric Point: 4.8000

>T61894 WP_042926284.1 NZ_CP014942:c131214-130900 [Rhodococcus sp. BH4]
VRPIHDAHLETLCPVLVLTRELVRPHLGTVTVAPVRAEGRGLSTELSLGEDNGVEDGSVVDCDGVTTIPVSALGVNRGFL
LPAQEVLLTRALRSAFDLESLGRQ

Download         Length: 315 bp

>T61894 NZ_CP014942:c131214-130900 [Rhodococcus sp. BH4]
GTGCGGCCAATCCATGACGCCCACCTCGAAACGCTCTGTCCGGTCTTGGTTCTGACGAGGGAGCTGGTTCGGCCTCATCT
GGGGACGGTCACTGTTGCTCCCGTTCGTGCGGAGGGGCGGGGGTTATCGACCGAGCTGAGTTTGGGCGAAGACAACGGTG
TCGAGGACGGATCGGTTGTCGACTGCGACGGGGTGACGACCATCCCGGTGTCGGCACTCGGGGTGAATCGAGGATTTCTC
TTGCCTGCTCAGGAAGTGTTGTTGACCAGGGCATTGCGATCAGCATTTGATCTCGAGTCATTAGGACGCCAGTAG

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 7870.93 Da        Isoelectric Point: 8.9167

>AT61894 WP_042926289.1 NZ_CP014942:c131436-131215 [Rhodococcus sp. BH4]
MSTQIAVRLPEDIVVFLDSEVSGGRAKSRAQVVLRALEREQRRQLAARDVEILSDGLGTGSDVNIAAAHGKKN

Download         Length: 222 bp

>AT61894 NZ_CP014942:c131436-131215 [Rhodococcus sp. BH4]
ATGAGCACGCAGATCGCGGTACGGCTACCCGAGGACATCGTGGTGTTTCTCGACAGTGAGGTCAGTGGTGGGCGCGCGAA
AAGCCGTGCTCAAGTTGTGCTTCGAGCGTTGGAGCGTGAGCAGCGTCGACAGCTTGCAGCCCGAGACGTGGAGATCTTGT
CTGATGGTCTCGGAACCGGTAGCGATGTGAATATCGCCGCCGCGCACGGGAAGAAGAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References