Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 2753640..2754156 Replicon chromosome
Accession NZ_CP014867
Organism Pseudomonas chlororaphis strain 189 isolate 189

Toxin (Protein)


Gene name stbE Uniprot ID A0A285EY61
Locus tag A3218_RS11905 Protein ID WP_009041601.1
Coordinates 2753640..2753921 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A285F0M2
Locus tag A3218_RS11910 Protein ID WP_062824057.1
Coordinates 2753911..2754156 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A3218_RS11885 2749900..2750796 - 897 WP_009041604.1 HlyD family secretion protein -
A3218_RS11890 2750793..2751002 - 210 WP_007932080.1 DUF1656 domain-containing protein -
A3218_RS11895 2750999..2753083 - 2085 WP_062824055.1 FUSC family protein -
A3218_RS11900 2753080..2753508 - 429 WP_062824056.1 winged helix DNA-binding protein -
A3218_RS11905 2753640..2753921 - 282 WP_009041601.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A3218_RS11910 2753911..2754156 - 246 WP_062824057.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
A3218_RS11915 2754219..2754464 - 246 WP_009041599.1 DUF2789 domain-containing protein -
A3218_RS11920 2754602..2755063 - 462 WP_062824058.1 YbaK/EbsC family protein -
A3218_RS11925 2755287..2756672 + 1386 WP_062824059.1 nodulation protein NfeD -
A3218_RS11930 2756674..2757432 + 759 WP_007932057.1 slipin family protein -
A3218_RS11935 2757398..2758402 - 1005 WP_062824060.1 aspartyl beta-hydroxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10879.81 Da        Isoelectric Point: 10.5797

>T61866 WP_009041601.1 NZ_CP014867:c2753921-2753640 [Pseudomonas chlororaphis]
MTYKLQFLPSARKEWDKLGHTLREQFKKKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Download         Length: 282 bp

>T61866 NZ_CP014867:c2753921-2753640 [Pseudomonas chlororaphis]
ATGACTTATAAGCTCCAGTTTCTGCCTTCGGCGCGCAAGGAATGGGACAAGCTCGGTCATACCCTGCGCGAGCAATTCAA
GAAGAAGCTGGCCGAGCGCCTGGAAATGCCACGGGTGCCCGCGGATGCCCTTCACGGCATGGCGGACTGCTACAAGATCA
AGCTCAAGGCCTCTGGCTATCGCCTGGTTTACCAAGTGATCGAGGATCAGGTGGTGGTTTCGGTGGTGGCCGTGGGCAAA
CGTGAACGCAGCGCCGTGTATGAGCGGGCACGAAAGCGCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8822.17 Da        Isoelectric Point: 5.0216

>AT61866 WP_062824057.1 NZ_CP014867:c2754156-2753911 [Pseudomonas chlororaphis]
MQSVLADKAVSVSELKKNPSAVLSGAHGGPVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Download         Length: 246 bp

>AT61866 NZ_CP014867:c2754156-2753911 [Pseudomonas chlororaphis]
ATGCAAAGCGTATTGGCTGATAAAGCTGTCAGCGTGTCTGAACTGAAAAAAAACCCCTCGGCTGTCCTGAGCGGCGCACA
CGGTGGTCCGGTTGCGGTGCTCAATCACAACCGGGTCATGGGCTATATGGTCCCGGCCGACGTGTTTGAAGCCATGATGG
AGCGTCTTGACGATCTTGAACTGGCGGAGATTGTCCGTGCCCGTCGGCACGAGACCCCGGTCCCGGTAAATCTGGATGAC
TTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A285EY61

Antitoxin

Source ID Structure
AlphaFold DB A0A285F0M2

References