Detailed information of TA system TA061864

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 2635756..2636426
• Replicon: chromosome
• Accession: NZ_CP014867
• Organism: Pseudomonas chlororaphis strain 189 isolate 189

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: A3218_RS11390
• Protein ID: WP_062824000.1
• Coordinates: 2635998..2636426 (+)
• Length: 143 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A2N8BIH3
• Locus tag: A3218_RS11385
• Protein ID: WP_062823999.1
• Coordinates: 2635756..2636001 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
A3218_RS11365	2631864..2632841	+	978	WP_009041696.1	taurine ABC transporter substrate-binding protein	-
A3218_RS11370	2632936..2633730	+	795	WP_062823997.1	taurine ABC transporter ATP-binding subunit	-
A3218_RS11375	2633727..2634566	+	840	WP_009041694.1	taurine ABC transporter permease TauC	-
A3218_RS11380	2634789..2635628	+	840	WP_062823998.1	taurine dioxygenase	-
A3218_RS11385	2635756..2636001	+	246	WP_062823999.1	hypothetical protein	Antitoxin
A3218_RS11390	2635998..2636426	+	429	WP_062824000.1	type II toxin-antitoxin system VapC family toxin	Toxin
A3218_RS11395	2636552..2637589	-	1038	WP_062824001.1	L-glyceraldehyde 3-phosphate reductase	-
A3218_RS11400	2637674..2638999	-	1326	WP_062824002.1	LLM class flavin-dependent oxidoreductase	-
A3218_RS11405	2639046..2641304	-	2259	WP_062824003.1	TonB-dependent receptor	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-127)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 143 a.a.
• Molecular weight: 15811.42 Da
• Isoelectric Point: 5.4927

>T61864 WP_062824000.1 NZ_CP014867:2635998-2636426 [Pseudomonas chlororaphis]
MIVLDTNVLSELMRPQPDASVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQMLHASALAMFEEDFIDRIVPFGT
QAALYYAHLISHRESLGRPISLVDAQIAAICRVHDAAIATRNAKDFSDTGLIVINPWLPLEV

Nucleotide

• Length: 429 bp

>T61864 NZ_CP014867:2635998-2636426 [Pseudomonas chlororaphis]
ATGATCGTGCTCGACACTAATGTGCTGTCGGAACTGATGCGTCCCCAACCGGACGCATCGGTATTGCTGTGGATCGAAGC
GCAACCTGTCGAAGACCTCTACATCAGCGCCATGACCATGGCCGAGATTCTTCACGGCATCGCGCGCCTGCCTCACGGCA
AGCGCAAACAGATGCTCCATGCGTCGGCGCTGGCGATGTTCGAGGAAGACTTCATCGACCGCATCGTGCCCTTCGGGACC
CAGGCGGCTCTTTACTACGCCCATCTGATTTCGCACCGGGAAAGCCTGGGGCGTCCGATCAGCTTGGTGGATGCGCAAAT
CGCGGCCATATGCCGCGTCCACGACGCGGCGATCGCCACCCGTAACGCCAAGGATTTCAGCGATACAGGGTTGATCGTTA
TCAACCCCTGGCTGCCACTCGAGGTTTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9129.35 Da
• Isoelectric Point: 7.3226

>AT61864 WP_062823999.1 NZ_CP014867:2635756-2636001 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALNRTTDSQGLASRIRARFAEAGGVKLELPERTEPARVVDLG
E

Nucleotide

• Length: 246 bp

>AT61864 NZ_CP014867:2635756-2636001 [Pseudomonas chlororaphis]
ATGGCCAGCCTGACAATCCGAAACCTGGACGACCACATCAAAGAGCGCCTGCGCATCGAGGCCGCCCACAACGGCCACTC
CATGGAAGAAGAAGCCCGCTTGATTTTGCGCCGCGCCCTGAACAGAACAACCGACAGCCAAGGCCTGGCCAGTCGTATCC
GGGCACGCTTTGCCGAGGCCGGCGGAGTGAAGCTTGAGCTGCCCGAACGTACCGAGCCGGCACGCGTGGTGGATCTGGGC
GAATGA

Structures

Antitoxin

• AlphaFold DB: A0A2N8BIH3