Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1369658..1370205 Replicon chromosome
Accession NZ_CP014867
Organism Pseudomonas chlororaphis strain 189 isolate 189

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A3218_RS05815 Protein ID WP_062823403.1
Coordinates 1369658..1369933 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag A3218_RS05820 Protein ID WP_062823404.1
Coordinates 1369933..1370205 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A3218_RS05805 1365538..1365975 - 438 WP_155736140.1 hypothetical protein -
A3218_RS30655 1366700..1367275 + 576 Protein_1166 transposase -
A3218_RS05810 1367355..1369558 - 2204 Protein_1167 Tn3 family transposase -
A3218_RS05815 1369658..1369933 - 276 WP_062823403.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
A3218_RS05820 1369933..1370205 - 273 WP_062823404.1 ribbon-helix-helix domain-containing protein Antitoxin
A3218_RS05825 1370227..1370963 - 737 Protein_1170 DUF2807 domain-containing protein -
A3218_RS31965 1371355..1371573 + 219 WP_162270012.1 hypothetical protein -
A3218_RS05830 1371623..1371874 + 252 WP_062823405.1 hypothetical protein -
A3218_RS05835 1371889..1372278 + 390 WP_062823406.1 hypothetical protein -
A3218_RS05840 1372287..1372523 + 237 WP_062823407.1 hypothetical protein -
A3218_RS05845 1372550..1373110 + 561 WP_062823408.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1296810..1378897 82087
- inside IScluster/Tn - - 1367355..1380052 12697


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10714.24 Da        Isoelectric Point: 5.8499

>T61861 WP_062823403.1 NZ_CP014867:c1369933-1369658 [Pseudomonas chlororaphis]
MELKWTSKAVSDITRLYEFLASVNQPAAARTVQQLTAAPTTLLTNPRIGECLEEFEPRDVRRIQIGQYEMRYEIVDSTIY
LLRLWHTREDR

Download         Length: 276 bp

>T61861 NZ_CP014867:c1369933-1369658 [Pseudomonas chlororaphis]
ATGGAATTGAAGTGGACAAGCAAGGCGGTTTCCGACATTACCCGACTGTACGAGTTTCTGGCCTCGGTGAATCAGCCTGC
CGCCGCACGAACAGTGCAGCAACTCACAGCCGCACCTACCACGCTGCTGACCAACCCGCGTATTGGCGAATGTCTGGAAG
AGTTCGAGCCAAGGGACGTACGCAGAATTCAGATCGGCCAATACGAGATGCGTTACGAGATAGTGGATTCCACTATCTAC
CTGTTGCGCCTGTGGCACACCCGCGAAGACCGATAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10036.29 Da        Isoelectric Point: 5.1007

>AT61861 WP_062823404.1 NZ_CP014867:c1370205-1369933 [Pseudomonas chlororaphis]
MATTAKTRSVTAHVPEQLAQKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGSVIDHQTVQAWADGL
STDTPLPVPR

Download         Length: 273 bp

>AT61861 NZ_CP014867:c1370205-1369933 [Pseudomonas chlororaphis]
ATGGCAACCACCGCGAAAACCCGATCTGTCACGGCCCACGTCCCTGAACAACTGGCCCAAAAGGTCGATTTGATGGCAGA
GCGTCTGGAGCGCTCCAAAAACTGGATCGTCAAGCAGGCTCTGTCCGCTTGGATAGACCAGGAAGAAGAGCGTAGTCGCC
TGACCCGTGAGGCCTTGGCTGATGTTGACGCTGGCAGCGTTATTGACCACCAAACCGTCCAGGCCTGGGCTGACGGTCTC
AGCACCGACACTCCGTTGCCGGTGCCGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References