Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1694251..1694770 Replicon chromosome
Accession NZ_CP014839
Organism Pandoraea thiooxydans strain ATSB16

Toxin (Protein)


Gene name relE Uniprot ID A0A0G3ELG6
Locus tag PATSB16_RS07775 Protein ID WP_047213572.1
Coordinates 1694251..1694532 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0G3ESX2
Locus tag PATSB16_RS07780 Protein ID WP_047213574.1
Coordinates 1694522..1694770 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PATSB16_RS07750 1689679..1690662 - 984 WP_052892615.1 Flp pilus assembly protein CpaB -
PATSB16_RS07755 1690685..1691182 - 498 WP_047213569.1 prepilin peptidase -
PATSB16_RS07760 1691282..1691461 - 180 WP_047216378.1 Flp family type IVb pilin -
PATSB16_RS07765 1692100..1693326 + 1227 WP_052892616.1 MFS transporter -
PATSB16_RS07770 1693353..1694102 - 750 WP_047213571.1 IclR family transcriptional regulator -
PATSB16_RS07775 1694251..1694532 - 282 WP_047213572.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PATSB16_RS07780 1694522..1694770 - 249 WP_047213574.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PATSB16_RS07785 1694855..1696153 - 1299 WP_047213576.1 tricarballylate/proton symporter TcuC -
PATSB16_RS07790 1696310..1697485 + 1176 WP_047213577.1 CoA transferase -
PATSB16_RS07795 1697482..1698252 + 771 WP_047213578.1 enoyl-CoA hydratase/isomerase family protein -
PATSB16_RS07800 1698269..1699102 + 834 WP_047213580.1 CoA synthetase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10589.33 Da        Isoelectric Point: 10.6505

>T61829 WP_047213572.1 NZ_CP014839:c1694532-1694251 [Pandoraea thiooxydans]
MSFELGFLDEALKEWRKLDASTREHFKAKLGERLANPRVPSAKLSGHANRYKIKLRNAGYRLVYEVRDSELIVVVVAVGK
CERAAVYKAAARR

Download         Length: 282 bp

>T61829 NZ_CP014839:c1694532-1694251 [Pandoraea thiooxydans]
ATGAGCTTTGAGCTGGGCTTTCTCGACGAGGCACTGAAGGAATGGCGCAAACTCGATGCGTCGACCCGGGAACACTTCAA
GGCCAAGTTAGGCGAGCGGCTGGCCAACCCGCGCGTGCCCAGCGCGAAGTTAAGCGGACATGCGAATCGTTACAAGATCA
AATTGCGCAACGCAGGCTATCGCCTGGTCTACGAAGTACGTGACAGCGAGTTGATCGTTGTAGTAGTCGCCGTAGGCAAG
TGCGAGCGAGCCGCAGTGTATAAAGCCGCGGCCCGGCGCTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8937.29 Da        Isoelectric Point: 4.2550

>AT61829 WP_047213574.1 NZ_CP014839:c1694770-1694522 [Pandoraea thiooxydans]
MPHRILAETTASVSELKRNPMGTVAAGDGLPVAILNRNEPAFYCVPAQAYEALMEKIEDMELNVIADARADQPVIKVTLD
EL

Download         Length: 249 bp

>AT61829 NZ_CP014839:c1694770-1694522 [Pandoraea thiooxydans]
ATGCCACATCGTATTCTCGCCGAGACCACCGCCAGCGTCTCTGAGCTCAAGCGCAACCCCATGGGGACCGTAGCCGCTGG
CGACGGGCTGCCGGTTGCGATTCTCAATCGCAATGAACCGGCCTTCTACTGCGTGCCGGCGCAAGCTTATGAAGCGTTGA
TGGAAAAAATCGAAGACATGGAGTTGAATGTCATCGCCGATGCTCGCGCCGACCAACCAGTCATCAAAGTAACGCTCGAT
GAGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0G3ELG6

Antitoxin

Source ID Structure
AlphaFold DB A0A0G3ESX2

References